2. AUTOMATION AND ROBOTICS IN DRUG DISCOVERY PROCESS Presented by, B.Abhinay, M.Pharm, Pharmacology, C.M.R.C.P . Under the guidance of, Ms. Meenu Singh, M.Pharm (Ph.D), Asst. Proffesor, C.M.R.C.P.
8. New Tools for Drug Discovery • Genomics • Proteomics • Bioinformatics • High-throughput screening • Combinatorial chemistry • Micro array technology
9. Drug Discovery & Development Target discovery Screening Lead-optimis-ation ADMET Develop-ment Registr-ation Where do Automation and Robotics play a key role?
12. DEFINITION: "A reprogrammable, multifunctional manipulator designed to move material, parts, tools, or specialized devices through various programmed motions for the performance of a variety of tasks" Robot Institute of America, 1979
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14. Types of Robots There are three types of industrial robots most commonly used in drug discovery and testing: (1) Cartesian (2) SCARA(selective compliance articulated robot arm) (3) Articulated.
29. References 1)DENSORobotics-Selecting Robots for Use in Drug Discovery and Testing 2) Medicinal Chemistry & Drug Discovery, Dr. Peter Wipf Department of Chemistry University of Pittsburgh http://ccc.chem.pitt.edu/wipf/index.html 3) AMRI-Drug Discovery and Development: Applications of Robotics and High-Throughput Instrumentation Brian T. Gregg, Ph.D. Research Fellow Medicinal Chemistry, June 25, 2007