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Pharmaceutical
Automation
Pharmaceutical Automation
In Laboratories
Many tests associated with research, discovery, and
development entail repetitive tasks such as moving
fluids between wells in a plate.
Pharmaceutical laboratories now use robots to perform
these tests because they are easy to automate using
traditional pick-and-place machines.
Robots provide a high degree of consistency and
accuracy i n executing the test protocols, while at the
same time allowing the researcher to focus on higher-
value tasks.
Another example is auto-sampler, which includes a
robot that picks up test tubes and loads them into a
nuclear magnetic resonance imaging magnet.
Pharmaceutical Automation
The flexibility of a robotic system is especially useful in
packaging applications such as primary packaging,
placing primary cartons in a case, and loading the case
on a pallet.
Such capabilities are particularly beneficial if a
company makes multiple products or different
product package configurations on a single production
line.
For example, if a company makes 60-count containers
of tablets and must add to the line a 300-count
container as well, then a robot would be able to handle
both package configurations on the line.
In Packaging
Pharmaceutical Automation
Robots are not appropriate for every pharmaceutical
process, and manufacturers should consider certain
criteria to determine where to apply this form of
automation.
In general, a highly repetitive and highly precise
process is a good candidate for roboticization.
Many robots perform at high speed and are adapted to
high-volume processes.
Robots could also perform low-volume operations
that completely consume an employee's time.
Criteria for using automation and robotics
Pharmaceutical Automation
Quality control is another criterion to consider.
If you want to have a highly repeatable process,
particularly if it's a fairly delicate process, robots are
extremely repeatable.
Robots also are a good choice in cleanrooms and other
operations where contamination must be controlled.
The machines can protect drugs from contamination
and shield humans from potentially harmful products
or processes.
Criteria for using automation and robotics
Pharmaceutical Automation
Economic conditions are raising the stakes and intensifying
the competition in the pharmaceutical industry.
Drug makers are intently seeking ways to reduce their
expenses, increase their efficiency, and make high-quality
products.
Robots can help companies achieve these ends by providing
speed, precision, repeatability, and flexibility.
Automation can improve discovery, pilot production, and
small-scale production, robots can be a particularly powerful
foundation for the growing biotechnology industry also.
Pharmaceutical Applications
Research and Development (R&D)
Robots now also play an essential role in the
development of new drugs. In high throughput
screening (H.T.S.) for instance, millions of
compounds are tested to determine which could
become new drugs. There is a need for the use of
robotics to test these millions of compounds.
Control Systems
Most robots have onboard controllers that
communicate with other machines' programmable
logic controllers (PLCs) or with personal computers
(PCs) networked to the line.
Pharmaceutical Applications
Laboratory Robotics:
This new technology allows human talents to be
concentrated on sample selection and submittal, and
scrutiny of the resulting data, rather than monotous
tasks that lead to boredom and mistakes.
Sterilization and Clean Rooms:
Robotics can be adapted to work in aseptic
environments. Clean room robots have features that
protect the sterile environment from potential
contamination.
Packaging Operations
Packaging processes, like other pharmaceutical
operations, benefit from the speed and repeatability
that automation brings.
Pharmaceutical Applications
Flexible Feeding:
Robots are also better than hard automation at flexible
feeding, a task that involves handling multiple types of
products or packages whose orientation always varies.
Vision Systems:
A vision system provides a valuable tool for
determining the accuracy of text and graphics in
pharmaceutical and medical packaging.
The chief benefit offered by adding a robot to the
vision system is speed.
It inspect insert in less than two minutes. The same
inspection performed by one operator and checked by
a second operator could take from 30 minutes to an
hour.
Pharmaceutical Applications
Grinding Applications:
Manual grinding is tough, dirty, and noisy work. The
metal dust produced by grinding is harmful to a
worker's eyes and lungs. Grinding robots save
manufacturing employees from having to endure
hazardous work environments.
Biopharma and Diagnostic Applications:
It provides standardized solutions that offer high
throughput and ensure reproducible, accurate results
in areas such as genomics, cells and proton sciences
and forensics.
It covers an extensive portfolio of biopharma
applications.
Pharmaceutical Applications
Sterile Syringe Filling
Stericlean, the result of three-way collaboration
between robotics specialist Staubli, factory automation
firm ATS and pharmaceutical manufacturer Sanofi-
Aventis, was introduced at Interphex with the claim
that it is the only robot arm on the market that can be
used in barrier isolation systems.
Stericlean has replaced manual processes and given us a
significant increase in productivity.
Advantages
Accuracy: Robotic systems are more accurate and
consistent than their human counterparts.
Tirelessness: A robot can perform a 96 man-hour project
in 10 hours with more consistency and higher quality
results.
Reliability: Robots can work 24 hours a day, seven days a
week without stopping or tiring.
Return on investment (ROI): There is quick turn- around
with ROI. Plus, with the increase in quality and application
speed, there are the benefits of increased production
possibilities.
Advantages
Affordability: With the advancements in technology and
affordable robotics becoming available at less cost, more
pick and place robotic cells are being installed for
automation applications.
Production: With robots, throughput speeds increase,
which directly impacts production. Because robots have the
ability to work at a constant speed without pausing for
breaks, sleep, vacations, they have the potential to produce
more than a human worker.
Quality: Robots have the capacity to dramatically improve
product quality.
Advantages
Speed: Robots work efficiently, without wasting movement
or time. Without breaks or hesitation, robots are able to
alter productivity by increasing throughput.
Flexibility: Packaging applications can vary. Robots are
easily reprogrammed.
Safety: Robots increase workplace safety. Workers are
moved to supervisory roles, so they no longer have to
perform dangerous applications in hazardous settings.
Savings: Greater worker safety leads to financial savings.
There are fewer healthcare and insurance concerns for
employers.
Advantages
Reduced chances of contamination: Removing people
from the screening process reduces the potential for
contamination and the potential for dropped samples when
handling them in laboratories.
Cost: Paybacks for the purchase of robotic equipment in the
pharmaceutical industry, given the fairly high hourly labor rates
paid to employees, number of production shifts, and the low
cost of capital.
Work continuously in any environment: Another advantage
in the laboratory is that robots are impervious to many
environments that would not be safe for humans.
Disadvantages
Expense: The initial investment of robots is
significant, especially when business owners are
limiting their purchases to new robotic equipment.
Dangers and fears: Although current robots are not
believed to have developed to the stage where they
pose any threat or danger to society, fears and
concerns about robots have been repeatedly expressed
in a wide range of books and films.
Expertise: Employees will require training in
programming and interacting with the new robotic
equipment.
Return on investment (ROI): Incorporating
industrial robots does not guarantee results.
Disadvantages
Safety: Robots may protect workers from some
hazards, but in the meantime, their very presence can
create other safety problems. These new dangers must
be taken in.
Harmful for human race
Un-employability
Robots willreplace 50% manpower.
Physical activity willdecrease and health problems
Learning capabilities will decrease.
Social life willbe affected
Emotions willbe decreased.
Future Prospects
Advancement in nono roboic field will be highly
useful for human being.
Nano-robots are so tiny machines that they can
traverse the human body very easily.
When a nano-robot enters into the body of a patient
would seek for infected cells and would repair them
without causing any damage to the healthy cells.
Thus these nano-robots when enter into human
bloodstream provide cell surgery and extreme life
prolongation.
Each nano-robot by itself will have limited
capabilities, but the coordinated effort of a multitude
willproduce the desired system level results.

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Unit 5c Pharmaceutical Automation-converted.pptx

  • 2. Pharmaceutical Automation In Laboratories Many tests associated with research, discovery, and development entail repetitive tasks such as moving fluids between wells in a plate. Pharmaceutical laboratories now use robots to perform these tests because they are easy to automate using traditional pick-and-place machines. Robots provide a high degree of consistency and accuracy i n executing the test protocols, while at the same time allowing the researcher to focus on higher- value tasks. Another example is auto-sampler, which includes a robot that picks up test tubes and loads them into a nuclear magnetic resonance imaging magnet.
  • 3. Pharmaceutical Automation The flexibility of a robotic system is especially useful in packaging applications such as primary packaging, placing primary cartons in a case, and loading the case on a pallet. Such capabilities are particularly beneficial if a company makes multiple products or different product package configurations on a single production line. For example, if a company makes 60-count containers of tablets and must add to the line a 300-count container as well, then a robot would be able to handle both package configurations on the line. In Packaging
  • 4. Pharmaceutical Automation Robots are not appropriate for every pharmaceutical process, and manufacturers should consider certain criteria to determine where to apply this form of automation. In general, a highly repetitive and highly precise process is a good candidate for roboticization. Many robots perform at high speed and are adapted to high-volume processes. Robots could also perform low-volume operations that completely consume an employee's time. Criteria for using automation and robotics
  • 5. Pharmaceutical Automation Quality control is another criterion to consider. If you want to have a highly repeatable process, particularly if it's a fairly delicate process, robots are extremely repeatable. Robots also are a good choice in cleanrooms and other operations where contamination must be controlled. The machines can protect drugs from contamination and shield humans from potentially harmful products or processes. Criteria for using automation and robotics
  • 6. Pharmaceutical Automation Economic conditions are raising the stakes and intensifying the competition in the pharmaceutical industry. Drug makers are intently seeking ways to reduce their expenses, increase their efficiency, and make high-quality products. Robots can help companies achieve these ends by providing speed, precision, repeatability, and flexibility. Automation can improve discovery, pilot production, and small-scale production, robots can be a particularly powerful foundation for the growing biotechnology industry also.
  • 7. Pharmaceutical Applications Research and Development (R&D) Robots now also play an essential role in the development of new drugs. In high throughput screening (H.T.S.) for instance, millions of compounds are tested to determine which could become new drugs. There is a need for the use of robotics to test these millions of compounds. Control Systems Most robots have onboard controllers that communicate with other machines' programmable logic controllers (PLCs) or with personal computers (PCs) networked to the line.
  • 8. Pharmaceutical Applications Laboratory Robotics: This new technology allows human talents to be concentrated on sample selection and submittal, and scrutiny of the resulting data, rather than monotous tasks that lead to boredom and mistakes. Sterilization and Clean Rooms: Robotics can be adapted to work in aseptic environments. Clean room robots have features that protect the sterile environment from potential contamination. Packaging Operations Packaging processes, like other pharmaceutical operations, benefit from the speed and repeatability that automation brings.
  • 9. Pharmaceutical Applications Flexible Feeding: Robots are also better than hard automation at flexible feeding, a task that involves handling multiple types of products or packages whose orientation always varies. Vision Systems: A vision system provides a valuable tool for determining the accuracy of text and graphics in pharmaceutical and medical packaging. The chief benefit offered by adding a robot to the vision system is speed. It inspect insert in less than two minutes. The same inspection performed by one operator and checked by a second operator could take from 30 minutes to an hour.
  • 10. Pharmaceutical Applications Grinding Applications: Manual grinding is tough, dirty, and noisy work. The metal dust produced by grinding is harmful to a worker's eyes and lungs. Grinding robots save manufacturing employees from having to endure hazardous work environments. Biopharma and Diagnostic Applications: It provides standardized solutions that offer high throughput and ensure reproducible, accurate results in areas such as genomics, cells and proton sciences and forensics. It covers an extensive portfolio of biopharma applications.
  • 11. Pharmaceutical Applications Sterile Syringe Filling Stericlean, the result of three-way collaboration between robotics specialist Staubli, factory automation firm ATS and pharmaceutical manufacturer Sanofi- Aventis, was introduced at Interphex with the claim that it is the only robot arm on the market that can be used in barrier isolation systems. Stericlean has replaced manual processes and given us a significant increase in productivity.
  • 12. Advantages Accuracy: Robotic systems are more accurate and consistent than their human counterparts. Tirelessness: A robot can perform a 96 man-hour project in 10 hours with more consistency and higher quality results. Reliability: Robots can work 24 hours a day, seven days a week without stopping or tiring. Return on investment (ROI): There is quick turn- around with ROI. Plus, with the increase in quality and application speed, there are the benefits of increased production possibilities.
  • 13. Advantages Affordability: With the advancements in technology and affordable robotics becoming available at less cost, more pick and place robotic cells are being installed for automation applications. Production: With robots, throughput speeds increase, which directly impacts production. Because robots have the ability to work at a constant speed without pausing for breaks, sleep, vacations, they have the potential to produce more than a human worker. Quality: Robots have the capacity to dramatically improve product quality.
  • 14. Advantages Speed: Robots work efficiently, without wasting movement or time. Without breaks or hesitation, robots are able to alter productivity by increasing throughput. Flexibility: Packaging applications can vary. Robots are easily reprogrammed. Safety: Robots increase workplace safety. Workers are moved to supervisory roles, so they no longer have to perform dangerous applications in hazardous settings. Savings: Greater worker safety leads to financial savings. There are fewer healthcare and insurance concerns for employers.
  • 15. Advantages Reduced chances of contamination: Removing people from the screening process reduces the potential for contamination and the potential for dropped samples when handling them in laboratories. Cost: Paybacks for the purchase of robotic equipment in the pharmaceutical industry, given the fairly high hourly labor rates paid to employees, number of production shifts, and the low cost of capital. Work continuously in any environment: Another advantage in the laboratory is that robots are impervious to many environments that would not be safe for humans.
  • 16. Disadvantages Expense: The initial investment of robots is significant, especially when business owners are limiting their purchases to new robotic equipment. Dangers and fears: Although current robots are not believed to have developed to the stage where they pose any threat or danger to society, fears and concerns about robots have been repeatedly expressed in a wide range of books and films. Expertise: Employees will require training in programming and interacting with the new robotic equipment. Return on investment (ROI): Incorporating industrial robots does not guarantee results.
  • 17. Disadvantages Safety: Robots may protect workers from some hazards, but in the meantime, their very presence can create other safety problems. These new dangers must be taken in. Harmful for human race Un-employability Robots willreplace 50% manpower. Physical activity willdecrease and health problems Learning capabilities will decrease. Social life willbe affected Emotions willbe decreased.
  • 18. Future Prospects Advancement in nono roboic field will be highly useful for human being. Nano-robots are so tiny machines that they can traverse the human body very easily. When a nano-robot enters into the body of a patient would seek for infected cells and would repair them without causing any damage to the healthy cells. Thus these nano-robots when enter into human bloodstream provide cell surgery and extreme life prolongation. Each nano-robot by itself will have limited capabilities, but the coordinated effort of a multitude willproduce the desired system level results.