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Madsen

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Madsen

  1. 1. Infrastructure to Enable P4 Medicine:<br />Investing in Innovative Personalized Health Solutions<br />OSU Annual Personalized Health Care National ConferenceOctober 6, 2011<br />
  2. 2. Why Personalized Health?<br />
  3. 3. International Comparison Health Expenditure, 1980–2008<br />Total expenditures on healthas percent of GDP<br />Average spending on healthper capita ($US PPP)<br />Source: OECD Health Data 2010 (Oct. 2010).<br />
  4. 4. An Aging Global Population<br />
  5. 5. Number of Practicing Physicians per 1,000 Population, 2008<br />* 2007.<br />** 2006.<br />Source: OECD Health Data 2010 (Oct. 2010).<br />
  6. 6. Average Annual Growth Rate of Practicing Physicians per 1,000 Population, 1998–2008<br />Percent<br />* 1997–2007.<br />** 1996–2006.<br />Source: OECD Health Data 2010 (Oct. 2010).<br />
  7. 7. Asthma Admission Rates per 100,000 Population Age 15 and Older, 2007<br />* 2006.<br />** 2005.<br />*** Among countries shown.<br />Source: OECD Health Care Quality Indicators Data 2009.<br />
  8. 8. Diabetes Acute Complications Admission Rates per 100,000 Population Age 15 and Older, 2007<br />* 2006.<br />** 2005.<br />*** Among countries shown.<br />Source: OECD Health Care Quality Indicators Data 2009.<br />
  9. 9. Congestive Heart Failure Admission Rates per 100,000 Population Age 15 and Older, 2007<br />* 2006.<br />** 2005.<br />*** Among countries shown.<br />Source: OECD Health Care Quality Indicators Data 2009.<br />
  10. 10. * 2006.<br />** 2005.<br />*** Among countries shown.<br />Source: OECD Health Care Quality Indicators Data 2009.<br />Diabetes Lower Extremity Amputation Rates per 100,000 Population Age 15 and Older, 2007*<br />
  11. 11. <ul><li>Shift spending from treatment to prevention
  12. 12. Create deeper engagement with health consumer
  13. 13. Provide clear, simple tools to the provider
  14. 14. Make it better, cheaper and faster </li></ul>The Big Need<br />The Six Trillion Dollar Man<br />
  15. 15. Two Key Innovations of Our Generation Transforming Personalized Health<br />
  16. 16. The Physic view of Personalized Health<br />Health is inherently personal and…<br />...one size does not fit all.<br />Personalized health uses precise tools and technologiesto measure an individual’s unique characteristics to enhance health.<br />
  17. 17. Where is Health Being Personalized?<br />Clinical Medicine<br />Drug Development <br />Consumer Products<br />Diagnostics<br />Insurance<br />PBMs<br />Clinical Nutrition<br />Food Safety<br />
  18. 18. What Does it Look Like?<br />Clinical Medicine<br />Consumer Products<br />Diagnostics<br />Drug Development <br />Insurance<br />PBMs<br />Clinical Nutrition<br />Food Safety<br />
  19. 19. It also looks like this<br />16<br />
  20. 20. And this..<br />17<br />
  21. 21. And this…<br />18<br />
  22. 22. And this…<br />19<br />
  23. 23. And this..<br />20<br />
  24. 24. And this..<br />21<br />
  25. 25. <ul><li>High unmet need
  26. 26. Supported by validated science
  27. 27. Actionable result
  28. 28. Informs meaningful decision about intervention (treatment/procedure) or behavior
  29. 29. Clinically Meaningful
  30. 30. Provides significant incremental benefit over use of existing tools
  31. 31. Demonstrates near-term benefit or cost-effectiveness
  32. 32. Alignment of Patient, Physician and Payer
  33. 33. Path to regulatory approval and reimbursement
  34. 34. Consumer-centric applications</li></ul>Our Criteria<br />
  35. 35. Key Personalized Health Priorities<br />Content<br />Enabling Platforms<br /><ul><li>Metabolic Disease (T2D/Obesity)
  36. 36. Mental Health
  37. 37. Cardiovascular Health
  38. 38. Reproductive Health
  39. 39. Cancer
  40. 40. Condition-Specific Nutritional Needs
  41. 41. Fitness
  42. 42. Food Safety and Security</li></li></ul><li>Innovation Spectrum<br />Actionability<br />
  43. 43. <ul><li>$12M Series C in 11/10 for PGD technology (Reproductive Health)
  44. 44. $11M Series B in 3/11 for PGx analysis of depression and anxiety therapies (Mental Health)
  45. 45. $30M Series C in 10/10 for diagnosis of Tissues of Origin (Cancer)
  46. 46. $18M Series A in 9/10 for pre-pregnancy screening (Reproductive Health)
  47. 47. $13M Series B in 7/11 for POC diagnostics for bloodstream infections (Infectious Disease)
  48. 48. $27M Series B in 7/11 for POC diagnostics for STDs (Infectious Disease)
  49. 49. $23M Series D in 8/11 for POC diagnostics for candida (Infectious Disease)
  50. 50. $18M Series B in 8/11 for inflammatory biomarkers for CVD (Cardiovascular)
  51. 51. $18M Series C in 9/11 for inflammatory biomarkers for RA (Autoimmune)</li></ul>VC Money Backing Innovation<br />
  52. 52. How do I feel?<br />

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