3. Whatare Fungi...???
• Fungi are a group of Unicellular & Multicellular Spore
producing organisms which are feeding on Organic
Matter.
• They occure in every habitats where Moisture and
Organic matter are available.
• These are Achlorophylous, hence can’t produce their
own food material.
• Most of the fungi Grows on Dead decaying organic
matter, hence called as Saprophytes.
• They are also Parasitic
4. Medicinal Usesof Fungi
• There are several fungi which are used as Medicines &
in the production of Medicine.
• These are as Follows :-
5. Antibiotics
• Antibiotics are metabolic substances produced by
some living organisms which are injurious to other living
beings
• Alexander fleming in 1944 for the first time extracted
the Wonder Drug “Penicillin” from the fungi
“Penicillium notatum”
6. Penicillium sp.
• First Antibiotic discovered
• It kills Bacteria by preventing them from making Cell wall
due to which the Bacteria dies.
Penicillium mould growing on Fruit
8. 3.
Fungi 1 Antibiotic Active against
(a
) Aspergillus fumigatus Fumigallin Entamoeba
A gigame us L Sarcin Tumour
A. niger Sorbic acid and
Jawaharin
Tumour Bacteria
A, prolifer tun Proliferin Tuberculosis Bacteria
tb
) Clavtctps purpurea Chrysergonic acid Micrococcus
<c
)
Gibberella baccara Buccal in A Bacteria and fungi
(d
>
Mucor rainannianus Ramycin Bacteria
(e
)
Penicillitim brefetdianum Brcfcldin Bacteria, fungi.
Tumour
P. chrysogenum Isopenicillin N Bacteria
P. notatum Pencil! in Bacteria
P. gtiseofnh um Griseofuivin Fungi
P. puberulum Puberulic acid
(0 Psalliorocumpestns Campestrm Bacteria
(g
) Usrilago maydis
Ustilagic acid and
ustic acid Fungi
Other Antibiotics Obtained from Fungi.
9. purpurea)
Contains some Alkaloids like Ergometrine, Ergotamine,
Ergosterol.
These are used for :
To induce Uterine contraction for Abortion.
Treatment of Menstural disorder.
To Check Haemorrhages
10. • Tolypocladium inflatum is soil mold which produces
Cyclosporine.
• It is actually a soil stage in the life cycle of a fungus called
Cordycep subsessilis.
• Cyclosporine is an immunosuppressant.
• Hence it is usually used at the time of organ transplant.
11. Aspergillus terreus
• Aspergillus terreus produces Lovastatin.
• Lovastatin is a drug used along a proper diet to reduce the
Bad Cholesterol and Fats(LDL) and raise Good
Cholesterols(HDL) in the blood.
• Lovastatin reduces the risk of Cardiovascular disease.
Aspergillus terms Culture Aspergillus terreus Conidiophore
NDC M458 962-10
Lovastatin
Tablets USP
40 mg
Rx Only
See the accompanying drug information sheet far
full cfrug information
Depress tab and pull dosage card out DO NOT
SEPARATE FROM PLASTIC SHELL
12. Pleurotus sp. (Oyster Mushroom)
• The oyster mushroom is another fungus that produces
Lovastatin.
13. Sachharomycescervisiae (Yeast)
• This fungi is used in the synthesis of a Drug called
Ephedrine
• Ephidrine is synthesized from Benzaldehydes by the action
of Yeast (Sachharomyces cervisiae)
• Used for treatment of Asthama and Nasal troubles.
14. • These are complex Organic compounds effective against
Arthritis, allergies, etc.
• They are also used in as Anesthetic and Antifertility agents.
• A wide variety of fungi has the ability of synthesizing
steroids such as, Cortisone is prepared by fermentation of
plant glycoside by Rhizopus nigricans & Aspergillus niger.
15. Ophiocordicepsinensis
• This is a very rare and very
expensive fungus and also known as
“Zombie mushroom”.
• It is used by athletes for boosting
metabolism and stamina
• It also increases and stimulates
testesteron and estrogen secretion.
• It has Anti-Diabetic properties.
• It has also been found that it also
improves lung functioning.
• Good for immune system
• It has also shown abilities to shrink
tumors of Cancer.
4^/
17. It boosts and regulates the Immune system.
It contains compounds that increase the
production of antibodies that fights pathogens
in the body.
Also lowers the bad Cholesterol like LDL.
• The ingrediants of this mushroom acts as anti
inflamatory agents.
• It is consumed in the form Of tea.
18. Trametessp. (Turkeytail Mushrooms)
• These mushrooms also have the ability to fight and cure
Cancer tumors.
• The most interesting compound in this mushroom is
Polysaccharide-K (PSK).
• This PSK is used as a priscription drug in the Traditional
Cancer treatment in Japan.
19. This mushroom has an Anti-Diabetic property by
maintaining the Insulin level in body
It also has some anti-inflammatory properties
It also has Cancer treating properties.
It also helps in the production of phagocytic cells in the
body.
20. Lentinulaedodes (Shiitake Mushrooms)
• This is an edible mushroom
• They contains two chemicals of interests i.e Lentinan
& Eritadenine.
• Lentinan boosts the immune system and helps to
fight Cancer.
• Eritadenine lowers the Cholesterol.
