Nepal has experienced several outbreaks of highly pathogenic avian influenza (HPAI) since 2009. The government implements disease control strategies like surveillance, stamping out infected flocks, and compensation. Surveillance is risk-based in high, medium, and low risk districts. Testing is done using rapid tests and RT-PCR. Positive samples are further characterized. Outbreaks are controlled through zonation and coordination committees. Legislation supports control efforts. While progress has been made in early detection and response, cross-border movement of birds and informal trade pose ongoing challenges to control of HPAI in Nepal.
COVID-19 is certainly a newly emerged zoonosis, not yet understood properly thus cases need utmost care in its handling in both in human and animals.
More observations and studies can only elucidate the origin, intermediate host and definitive host (till date humans) and maintenance host of SARS CoV-2.
For control of emerging and re-emerging zoonoses potentiating one health environmental approach for understanding disease drivers and control strategies are essential elements.
CASE PRESENTATION and PREVENTIVE STRATEGIES OF AIDS including ...
(1) primary and secondary prevention of aids
(2) Pre-Exposure Prophylaxis (PrEP) POST-exposure prophylaxis ( PEP)
One Health research at ILRI to address neglected tropical diseases, zoonoses ...ILRI
Presentation by Hung Nguyen-Viet, Fred Unger, Hu Suk Lee, Johanna Lindahl, Thang Nguyen, Bernard Bett, Eric Fèvre, Sothyra Tum, Sinh Dang-Xuan, Arshnee Moodley and Delia Grace at a webinar by the One Health Collaborating Center Universitas Gadjah Mada, ‘World Zoonoses Day 2020: Lessons learned and future directions’, 7 July 2020.
COVID-19 is certainly a newly emerged zoonosis, not yet understood properly thus cases need utmost care in its handling in both in human and animals.
More observations and studies can only elucidate the origin, intermediate host and definitive host (till date humans) and maintenance host of SARS CoV-2.
For control of emerging and re-emerging zoonoses potentiating one health environmental approach for understanding disease drivers and control strategies are essential elements.
CASE PRESENTATION and PREVENTIVE STRATEGIES OF AIDS including ...
(1) primary and secondary prevention of aids
(2) Pre-Exposure Prophylaxis (PrEP) POST-exposure prophylaxis ( PEP)
One Health research at ILRI to address neglected tropical diseases, zoonoses ...ILRI
Presentation by Hung Nguyen-Viet, Fred Unger, Hu Suk Lee, Johanna Lindahl, Thang Nguyen, Bernard Bett, Eric Fèvre, Sothyra Tum, Sinh Dang-Xuan, Arshnee Moodley and Delia Grace at a webinar by the One Health Collaborating Center Universitas Gadjah Mada, ‘World Zoonoses Day 2020: Lessons learned and future directions’, 7 July 2020.
Introduction of African swine fever activities in VietnamILRI
Presentation by Hu Suk Lee at an international workshop on veterinary epidemiology hosted by the Animal and Plant Quarantine Agency, Ministry of Agriculture, Food and Rural Affairs, South Korea, 17 June 2020.
Washington Global Health Alliance Discovery Series
Supamit Chinsuttiwat
May 22, 2008
'Response to Avian Influenza and Preparedness for Pandemic Influenza: Thailand's Experience'
Epidemiological investigation of Peste des petits ruminants virus in small ru...ILRI
Poster prepared by Biruk Alemu, Getachew Gari, Barbara Wieland, Bewket Siraw, Wondweson Asfaw, Samuel Mulat, Daniel Tekesete, Demeke Sibhat and Reta Duguma, September 2016
The European Commission for the Control of Foot-and-Mouth Disease (EuFMD), one of FAO’s oldest Commissions, came into being on the 12th June 1954, with the pledge of the sixth founding member state to the principles of a coordinated and common action against Foot-and-mouth Disease.
The prevalence of tuberculosis and Rifampicin-resistant tuberculosis (RMP-TB) among patients showing symptoms of tuberculosis that visited Federal Medical Centre, Yenagoa, Bayelsa state, Nigeria was determined from June 2015 to December 2015. A total of 456 patients comprising 218(47.8%) males and 238(52.2%) females were examined using their sputum and gastric lavage samples. GeneXpert System was used to determine the TB and RMF-TB. Results showed that out of the 456 patients, overall tuberculosis prevalence was 88(19.3%), males recorded 48(10.5%) while females had 40(8.8%). The highest tuberculosis prevalence was recorded amongst 21-30 years and 31-40 years age groups (5.5%). Out of the 456 patients, total prevalence for Rifampicin resistance was 11(2.4%). Of these, females and male prevalence was 6(1.3%) and 5(1.1%) respectively. There was no significant difference (P>0.05) in prevalence between age and gender. The treatment and follow-up of existing cases is a key to preventing the spread of multi drug-resistant tuberculosis.
Presentation 2.11 Specific pathogen-free (SPF), specific pathogen-resistant (...ExternalEvents
http://www.fao.org/documents/card/en/c/28b6bd62-5433-4fad-b5a1-8ac61eb671b1/
FAO Second International Technical Seminar/Workshop on Acute hepatopancreatic necrosis disease (AHPND) There is a way forward! FAO Technical Cooperation Programme: TCP/INT/3501 and TCP/INT/3502.
African Swine Fever (ASF) control: An entry point for enhancing human welfare...ILRI
Presented by Richard Bishop, Jocelyn Davies, Cynthia Onzere, Steve Kemp, Vish Nene, Guenther Keil, Marisa Arias and Edward Okoth at the ILRI BioSciences Day, Nairobi, 27 November 2013
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Current Management Status of Highly Pathogenic Avian Influenza (HPAI) in Nepal
1. Current Management Status of
Highly Pathogenic Avian
Influenza (HPAI) in Nepal
Prepared by:
Dr. Krishna Prasad Acharya
Regional Veterinary Laboratory, Pokhara, Nepal
Presented by:
Dr. Kedar Raj Pande
Senior Veterinary Officer,
Regional Veterinary Laboratory, Pokhara
2. The Country
• Land locked country
• Birth place of Lord Buddha
• Bordering countries:
– China : North
– India: East, south and west
• Geographical region
– Himalayan:
• 8 out of 14 highest summits in
the world including Mt. Everest
– Mountain/hill :
– Terai: (Mostly bordering with
India)
• Altitude ranges from 70 meters
to 8,848 meters
NEPAL
4. General Background
Poultry Population :
Poultry (Chicken) – 68.63 Millions
Duck – 0.39 Million.
(Source: MoLD 2016)
Total poultry comprises of;
55% commercial
45% backyard chicken
(Source: MoLD 2016)
5. Importance of Poultry
Like many other developing country, in Nepal poultry
occupies a unique position in term of its
contribution in providing:
Cheaper source of high protein food
Cash income particularly to rural poor
• Contribution: AGDP: 4%, and employment to >
one million people.
• Total investment : – NRs. 16 Billion.
11. Situation of HPAI in Nepal
From 2006 - surveillance of Avian Influenza
was started
In 2009 - first outbreak was reported in
Jhapa district.
In 2010- Seven outbreaks was reported
From 2010-12- 42 outbreaks was reported in
different part of 18 districts
In 2013- 173 outbreaks occurred in different
part of 12 districts.
12. Contd………Contd………
In 2017 – 3 outbreaks of HPAI are reported
from Kaski and Sunsari Districts.
All the outbreaks were controlled by stamping
out operation
Surveillance activities intensified around
infected zone and through out the country.
No human cases identified so far.
13. Virus Clade reported
Year of
Outbreak
Clade
2009 2.2 (similar to west Bengal and
Bangladesh)
2010 2.3.2 (Similar to Mongolia) and 2.2
2011-2013 2.3.2.1 (Hubei like) and 2.3.2.1a
2017 2.3.2.1a similar to previous outbreak
15. Situation of Outbreak, 2017Situation of Outbreak, 2017
S.N Date Species Address Results Result from OIE
Reference
Lab(Zeelong
Australia)
1 2017/02/23 BD Pokhara-18,
Kaski
H5N1 H5N1
2 2017/03/01 BC Pokhara-
18,Kaski
H5N1 H5N1
3 2017/03/03 BC Pokhara-18,
Kaski
H5N1 H5N1
4 2017/03/05 WB Itahari,
Sunsari
H5N1 H5N1 & H5N8
5 2017/03/08 CL Khanar,
Sunsari
H5N8 H5N8
H5N1 Virus Clade : 2.3.2.1a
H5N8 Virus Clade : 2.3.4.4
16. WHAT ARE WE DOING IN
NEPAL FOR THE CONTROL
OF HPAI ?
17. DISEASE CONTROL STRATEGIES
1.PRE-OUTBREAK
- EARLY DETECTION
- SURVEILLANCE (PASSIVE AND ACTIVE)
- IMPROVED BIO-SECURITY ON FARMS
2. DURING OUTBREAK
STAMPING OUT
- CULLING/ KILLING
- DISPOSAL, CLEANING AND DISINFECTION OF
INFECTED PREMISES
- QUARANTINE AND MOVEMENT CONTROL
- COMPENSATION
3. POST OUTBREAK
- POST OPERATIVE SURVEILLANCE PLAN (POSP)
- RESTOCKING
18. Central (CVL/VEC/DAH / DLS)
Local
Livestock Service Centre/Sub-Centre
Private Veterinarian or Owners of Domestic Animals
Outbreaks/ Suspected cases of notifiable disease
①Notify
Disease Control
Guidelines
Other
Prefectural
Government
Other
Prefectural
Government
RDLS/RVL/
NADIL
②Notify ④Report
③Order for Control Measures
District Livestock Services Office
National Disease Notification System
International (OIE)
19. HPAI Surveillance in Nepal
(Risk based Surveillance)
Risk Based Surveillance
• 22 HRD
• 21 MRD
• 32 LRD
• 8 Water bird zone
20. Contd..
•Risk based surveillance system is being implemented
•Based on risk, country has divided into three risk categories:
• High risk districts
• Medium risk districts
• Low risk districts
– Clinical surveillance followed by sample collection (dead birds,
Tracheal and cloacal swabs) from sick and dead chicken
–Serum samples are collected from sick and healthy ducks
–Fresh Feces from wild water birds and birds from Live markets
21. Testing Methods
• Screening of the samples by Rapid test to detect Avian
influenza A using Rapid test kit (Symbiotic and Anigen)
• All RDT positive samples and 10% of negative samples are
tested by RT-PCR or Real time PCR (RRT- PCR) for
confirmation of H5 and N1 antigen at national Laboratory
• Molecular characterization - is done from OIE reference lab
(VLA, Weybridge, UK) and AAHL, Gilong, Australia .
• Currently, no virus inoculation is done in the National
Laboratory for HPAI virus.
22. Control Strategy: Zonation of outbreak area
Infected Farm (epicenter)
Infected Zone (0- up to 3 km.)
High Risk Zone (3- 10 km.)
Restricted Zone
Regular Surveillance
(Whole Country)
23. Coordination and Implementation
Mechanism
National Disaster Relief Co-ordination
Committee (NDRCC)
Regional Disaster Relief
Co-ordination
Committee (RDRCC)
District Disaster Relief
Co-ordination
Committee (DDRCC)
Sub-committee on
Control of Avian
Influenza (SCAI)
Regional Avian Influenza Co-ordination
Committee (RAICC)
District Avian Influenza Co-
ordination committee (DAICC)
Avian Influenza Technical Co-
ordination Committee (AITCC)Administrative
directives
Technical
directives
Technical
directives
Administrative
directives
Stamping out
Rapid Response
Team (RRT)
National Bird Flu Control
Committee
24. LEGISLATIVE SUPPORT
Natural Disaster Relief Act, 1982
Animal Health and Livestock ServicesAnimal Health and Livestock Services
Act, 1998 and its Regulation, 1999Act, 1998 and its Regulation, 1999
Bird Flu Disease Control Order, 2008
(Amendment, 2009 --- 2017)
Standard Operating Procedure, 2011
Animal Transportation Standard, 2007
25. Poultry products destroyed and
compensation paid during stamping-out
operation
Year
Destroyed items
Poultry
(No)
Eggs(No) Meat
(Kg)
Feed
(Kg)
Till 2014 19,65,315 30,53,083 1555.5 1,62,733
2017 5289 903 105 1196
Total
1970604 3053986 16510.5 163929
Total compensation
paid
NRs
38,06,44,000
26. SOME TRENDS
• Disease situation improving, this year only two
outbreaks since 2014
• Capacity enhancement
– Grass roots surveillance improved through
– Early detection and response capacity
– Laboratories well equipped, most laboratories can make
diagnosis
– Improve response capacity in the field of HPAI and
other TADs and EIDs
– Improve awareness of HPAI in the region and
countrieS
27. ONGOING INTERVENTIONS
– Public awareness programmes
– Surveillance sampling
– Regulation of livestock movement
– Following quarantine procedure for export and
import of live livestock and poultry and its products.
– Regulation on import of chicks and other poultry and
livestock products from the infected countries
– Improvements in farm bio-security
– Live bird market improvement
28. SUCCESS TO DATE
• Successfully contained the outbreak.
• Reduced the number of outbreak and prevented
the further spread of the virus.
• Prevented human infection of H5N1.
• Preparedness in tackling with future possible
pandemic
29. CONSTRAINTS
• Long porous border with India.
• Cross border movement of birds.
• Uncontrolled movement of birds and other
livestock products
• Informal trade and unmanaged local market
• Backyard poultry population
• Unregistered small scattered poultry farms
with poor biosecurity
30. • Virus is breaking the climate barrier
• Not limited to high or medium risk areas.
• Resources are much limited for compensation
• New strains are evolving
• Long porus border difficult to control and monitor
• Nepal on migratory bird route
• Farmers cooperation is always favorable.
CHALLENGES BECAUSE…….