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Reproduction
- the creation of new individuals
from existing ones.
2 principal modes:
 Asexual
 Sexual
 Asexual reproduction
- (reproduction without sex) is the
creation of genetically identical offspring by a
lone parent.
Types of Asexual reproduction:
 Budding- splitting off new individuals from
outgrowths of existing ones
 Fission- the separation of a parent into two or
more individuals of about equal size.
 Fragmentation-Regeneration- the breaking of
the parent body into several pieces, followed
by regeneration, the regrowth of lost body
parts.
ADVANTAGES (Asexual Reproduction):
 It allows animals that do not move from
place to place or that live in isolation to
produce offspring without finding mates.
 it enables an animal to produce many
offspring quickly; no time or energy is lost in
production of eggs and sperm or in mating
DISADVANTAGE:
 It produces genetically uniform populations.
 Sexual reproduction
- the creation of offspring through
the process of fertilization, the fusion of two
haploid (n) sex cells, or gametes, to form a
diploid (2n) zygote (fertilized egg).
 Sperm- a male gamete, is a relatively small
cell that moves by means of a flagellum.
 Egg- female gamete, is a much larger cell
that is not self-propelled.
 Zygote- the new individual it develops into,
contains a unique combination of genes
inherited from the parents via the egg and
sperm.
How to find a mate?
 Hermaphroditism
- in which each individual has both
female and male reproductive systems.
 External
fertilization
- The
parents discharge
their gametes into
the water, where
fertilization then
occurs, often without
the male and
female even making
physical contact.
2 Mechanics of Fertilization:
 Internal fertilization-
occurs when sperm
are deposited in or
close to the female
reproductive tract
and gametes unite
within the tract.
2 Mechanics of Fertilization:
In terms of genetic makeup, what is
the most important difference
between the outcome of sexual
reproduction and that of asexual
reproduction?
The offspring of sexual reproduction are
genetically diverse, whereas the offspring of
asexual reproduction is genetically identical.
 Ovaries
- woman’s gonad,
are each about an
inch long, with a
bumpy surface
 The bumps are follicles, each
consisting of one or more layers of
cells that surround, nourish, and
protect a single developing egg
cell.
 An immature egg cell is ejected from the
follicle in a process called ovulation.
 the follicular tissue
that had been
surrounding the
egg that was just
ejected grows
within the ovary to
form a solid mass
called the corpus
luteum
 secretes additional
estrogen as well as
progesterone, a hormone
that helps maintain the
uterine lining during
pregnancy.
Corpus luteum
 If the released
egg is not
fertilized, the
corpus luteum
degenerates,
and a new
follicle matures
during the next
cycle.
 each ovary lies next to
the opening of an
oviduct, also called a
fallopian tube.
 The oviduct
opening
resembles a
funnel fringed
with finger-like
projections.
Uterus
 known as the womb, is
the actual site of
pregnancy.
 about 3 inches long in
a woman who has
never been pregnant.
 The uterus has a thick
muscular wall, and its
inner lining, the
endometrium, is richly
supplied with blood
vessels.
 The term embryo is
used for the stage
in development
from the first
division of the
zygote until body
structures begin to
appear, about the
9th week in
humans.
From the 9th week until
birth, a developing
human is called a fetus.
 An ectopic
pregnancy is a
serious medical
emergency that
requires surgical
intervention;
otherwise, it can
rupture surrounding
tissues, causing
severe bleeding
and even death of
the mother.
 The narrow neck at the bottom of the
uterus is the cervix, which opens into the
vagina.
 The cervix opens
to the vagina, a
thin-walled, but
strong, muscular
chamber that
serves as the
birth canal
through which
the baby is born.
 Vulva is the
collective term for
the external
female genitalia.
 A pair of slender
skin folds, the labia
minora, border the
openings.
 a pair of thick,
fatty ridges, the
labia majora,
protect the
vaginal opening.
 The vagina, labia
minora, and a small
erectile organ called
the clitoris all engorge
with blood and enlarge
during sexual activity.
Where does fertilization
occur? In which organ
does the fetus develop?
 The Oviduct
 The uterus
 The male gonads,
or testes (singular,
testis), are each
housed outside the
abdominal cavity
in a sac called the
scrotum.
 A testis and
scrotum together
are called a
testicle.
 From each testis,
sperm pass into a
coiled tube called
the epididymis,
which stores the
sperm while they
continue to
develop.
 Sperm leave the
epididymis during
ejaculation, the
expulsion of
sperm-containing
fluid from the
penis.
 Next to the bladder, the vas deferens joins a
short duct from a gland, the seminal vesicle.
 The two ducts unite to form a short
ejaculatory duct, which joins its counterpart
conveying sperm from the other testis.
 At that time, muscular contractions propel the
sperm from the epididymis through another
duct called the vas deferens.
 The vas deferens passes upward into the
abdomen and loops around the urinary
bladder.
Three sets of glands:
 Seminal vesicles (2)- secrete a thick
fluid that contains fructose, which
provides most of the energy used by the
sperm as they propel themselves through
the female reproductive tract.
 Prostate gland- secretes a thin fluid
that further nourishes the sperm.
 Bulbourethral glands (2)- secrete a
clear, alkaline mucus.
 Together, the sperm and the glandular
secretions make up semen, the fluid
ejaculated from the penis during orgasm,
a series of rhythmic, involuntary
contractions of the reproductive structures.
 About 2–5 mL (1 teaspoonful) of semen
are discharged during a typical
ejaculation.
 About 95% of the fluid consists of glandular
secretions, 5% is made up of sperm
(typically 200–500 million of them), only
one of which may eventually fertilize an
egg.
 Reproductive cycle
- a recurring sequence of events that
produces eggs, makes them available for
fertilization, and prepares the body for
pregnancy.
 Ovarian cycle
- cyclic events that occur about every 28
days in the human ovary.
 Changes in the uterus define the
menstrual cycle.
Sexually transmitted diseases (STDs) are
contagious diseases spread by sexual contact.
 Contraception is the deliberate prevention
of pregnancy.
 A woman may have a tubal ligation
(“having her tubes tied”), in which a doctor
removes a short section from each oviduct,
often tying (ligating) the remaining ends.
 A man may undergo a vasectomy, in which
a doctor cuts a section out of each vas
deferens to prevent sperm from reaching
the urethra.
Contraception can prevent
unwanted pregnancy
 Temporary abstinence, also called the
rhythm method or natural family planning,
depends on refraining from intercourse
during the days around ovulation, when
fertilization is most likely.
 Oral contraceptives, or birth control pills,
come in several different forms that
contain synthetic estrogen and/or
progesterone (or a synthetic
progesterone- like hormone called
progestin).
What is the fundamental
difference between barrier
methods (such as condoms)
and oral contraceptives in terms
of their means of preventing
pregnancies?
Barrier methods prevent sperm
from reaching an egg, while
birth control pills prevent the
release of eggs altogether.
 Pregnancy, or gestation
- is the carrying of developing young
within the female reproductive tract.
 Human pregnancy averages 266 days (38
weeks) from fertilization (also called
conception in humans), or 40 weeks (9
months) from the start of the last menstrual
cycle.
Affects the Embryo:
1. German measles virus- can cause
serious birth defects
2. HIV- HIV-infected babies usually die of
AIDS within a few years without
treatment.
3. Alcohol and the chemicals in tobacco
smoke, for instance, raise the risk of
miscarriage and birth defects.
4. Alcohol can cause a set of birth defects
called fetal alcohol syndrome, which
includes mental retardation.
 First Trimester
 Second Trimester
 Third Trimester
Certain drugs cause their most
serious damage to an embryo
very early in pregnancy, often
before the mother even realizes
she is pregnant. Why?
Because organ systems, such as
circulatory and nervous systems,
begin to develop in the first trimester.
 The series of events that
expel an infant from the
uterus is called labor.
 Estrogen- trigger the
formation of numerous
oxytocin receptors on
cells of the uterus.
 Oxytocin- stimulates the
smooth muscles in the
wall of the uterus,
producing the series of
increasingly strong,
rhythmic contractions
characteristic of labor.
 Prostaglandins, local
tissue regulators that
stimulate the uterine
muscle cells to contract
even more.
The induction of labor involves
positive feedback, a type of
control in which a change
triggers mechanisms that
amplify that change.
 The first stage,
dilation, is the time
from the onset of
labor until the cervix
reaches its full
dilation of about 10
cm. Dilation is the
longest stage of
labor, lasting 6–12
hours or even
considerably longer.
 Expulsion stage.
Strong uterine
contractions, lasting
about 1 minute
each, occur every 2–
3 minutes, and the
mother feels an
increasing urge to
push or bear down
with her abdominal
muscles.
 Delivery of the
placenta.
(“afterbirth”),
usually within 15
minutes after the
birth of the baby.
 Prolactin and
oxytocin promote
milk production
and release (called
lactation) by the
mammary glands.
Reproductive technologies increase our
reproductive options
 About 15% of couples who want children are
unable to conceive, even after 12 months of
unprotected intercourse. Such a condition,
called infertility, can have many causes.
 Infertility is caused by impotence, also called
erectile dysfunction, the inability to maintain
an erection.
Reproductive technologies increase our
reproductive options
 Female infertility can result from a lack of
eggs, a failure to ovulate, or blocked
oviducts (often caused by scarring due to
sexually transmitted diseases).
 Other women are able to conceive, but
cannot support a growing embryo in the
uterus. The resulting multiple miscarriages
can take a heavy emotional toll.
 Drug therapies (including Viagra) and
penile implants can be used to treat
impotence.
 If a woman has normal eggs that are not
being released properly, hormone injections
can induce ovulation.
 If a woman produces eggs but is unable
to support a growing fetus, she and her
partner may hire a surrogate mother.
 Many infertile couples turn to fertilization
procedures called assisted reproductive
technologies.
 In vitro fertilization (IVF), the most common
assisted reproductive technology
procedure, a woman’s eggs are mixed with
sperm in culture dishes (in vitro means “in
glass”) and incubated for several days to
allow fertilized eggs to start developing.

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Reproduction and human development

  • 1.
  • 2. Reproduction - the creation of new individuals from existing ones. 2 principal modes:  Asexual  Sexual
  • 3.  Asexual reproduction - (reproduction without sex) is the creation of genetically identical offspring by a lone parent. Types of Asexual reproduction:  Budding- splitting off new individuals from outgrowths of existing ones  Fission- the separation of a parent into two or more individuals of about equal size.  Fragmentation-Regeneration- the breaking of the parent body into several pieces, followed by regeneration, the regrowth of lost body parts.
  • 4.
  • 5. ADVANTAGES (Asexual Reproduction):  It allows animals that do not move from place to place or that live in isolation to produce offspring without finding mates.  it enables an animal to produce many offspring quickly; no time or energy is lost in production of eggs and sperm or in mating DISADVANTAGE:  It produces genetically uniform populations.
  • 6.  Sexual reproduction - the creation of offspring through the process of fertilization, the fusion of two haploid (n) sex cells, or gametes, to form a diploid (2n) zygote (fertilized egg).  Sperm- a male gamete, is a relatively small cell that moves by means of a flagellum.  Egg- female gamete, is a much larger cell that is not self-propelled.  Zygote- the new individual it develops into, contains a unique combination of genes inherited from the parents via the egg and sperm.
  • 7.
  • 8. How to find a mate?  Hermaphroditism - in which each individual has both female and male reproductive systems.
  • 9.  External fertilization - The parents discharge their gametes into the water, where fertilization then occurs, often without the male and female even making physical contact. 2 Mechanics of Fertilization:
  • 10.  Internal fertilization- occurs when sperm are deposited in or close to the female reproductive tract and gametes unite within the tract. 2 Mechanics of Fertilization:
  • 11. In terms of genetic makeup, what is the most important difference between the outcome of sexual reproduction and that of asexual reproduction? The offspring of sexual reproduction are genetically diverse, whereas the offspring of asexual reproduction is genetically identical.
  • 12.  Ovaries - woman’s gonad, are each about an inch long, with a bumpy surface  The bumps are follicles, each consisting of one or more layers of cells that surround, nourish, and protect a single developing egg cell.
  • 13.  An immature egg cell is ejected from the follicle in a process called ovulation.  the follicular tissue that had been surrounding the egg that was just ejected grows within the ovary to form a solid mass called the corpus luteum
  • 14.  secretes additional estrogen as well as progesterone, a hormone that helps maintain the uterine lining during pregnancy. Corpus luteum  If the released egg is not fertilized, the corpus luteum degenerates, and a new follicle matures during the next cycle.
  • 15.  each ovary lies next to the opening of an oviduct, also called a fallopian tube.  The oviduct opening resembles a funnel fringed with finger-like projections.
  • 16. Uterus  known as the womb, is the actual site of pregnancy.  about 3 inches long in a woman who has never been pregnant.  The uterus has a thick muscular wall, and its inner lining, the endometrium, is richly supplied with blood vessels.  The term embryo is used for the stage in development from the first division of the zygote until body structures begin to appear, about the 9th week in humans. From the 9th week until birth, a developing human is called a fetus.
  • 17.  An ectopic pregnancy is a serious medical emergency that requires surgical intervention; otherwise, it can rupture surrounding tissues, causing severe bleeding and even death of the mother.
  • 18.  The narrow neck at the bottom of the uterus is the cervix, which opens into the vagina.  The cervix opens to the vagina, a thin-walled, but strong, muscular chamber that serves as the birth canal through which the baby is born.
  • 19.  Vulva is the collective term for the external female genitalia.  A pair of slender skin folds, the labia minora, border the openings.
  • 20.  a pair of thick, fatty ridges, the labia majora, protect the vaginal opening.  The vagina, labia minora, and a small erectile organ called the clitoris all engorge with blood and enlarge during sexual activity.
  • 21. Where does fertilization occur? In which organ does the fetus develop?  The Oviduct  The uterus
  • 22.
  • 23.  The male gonads, or testes (singular, testis), are each housed outside the abdominal cavity in a sac called the scrotum.  A testis and scrotum together are called a testicle.
  • 24.  From each testis, sperm pass into a coiled tube called the epididymis, which stores the sperm while they continue to develop.  Sperm leave the epididymis during ejaculation, the expulsion of sperm-containing fluid from the penis.
  • 25.  Next to the bladder, the vas deferens joins a short duct from a gland, the seminal vesicle.  The two ducts unite to form a short ejaculatory duct, which joins its counterpart conveying sperm from the other testis.
  • 26.  At that time, muscular contractions propel the sperm from the epididymis through another duct called the vas deferens.  The vas deferens passes upward into the abdomen and loops around the urinary bladder.
  • 27. Three sets of glands:  Seminal vesicles (2)- secrete a thick fluid that contains fructose, which provides most of the energy used by the sperm as they propel themselves through the female reproductive tract.  Prostate gland- secretes a thin fluid that further nourishes the sperm.  Bulbourethral glands (2)- secrete a clear, alkaline mucus.
  • 28.  Together, the sperm and the glandular secretions make up semen, the fluid ejaculated from the penis during orgasm, a series of rhythmic, involuntary contractions of the reproductive structures.  About 2–5 mL (1 teaspoonful) of semen are discharged during a typical ejaculation.  About 95% of the fluid consists of glandular secretions, 5% is made up of sperm (typically 200–500 million of them), only one of which may eventually fertilize an egg.
  • 29.  Reproductive cycle - a recurring sequence of events that produces eggs, makes them available for fertilization, and prepares the body for pregnancy.  Ovarian cycle - cyclic events that occur about every 28 days in the human ovary.  Changes in the uterus define the menstrual cycle.
  • 30. Sexually transmitted diseases (STDs) are contagious diseases spread by sexual contact.
  • 31.  Contraception is the deliberate prevention of pregnancy.  A woman may have a tubal ligation (“having her tubes tied”), in which a doctor removes a short section from each oviduct, often tying (ligating) the remaining ends.  A man may undergo a vasectomy, in which a doctor cuts a section out of each vas deferens to prevent sperm from reaching the urethra. Contraception can prevent unwanted pregnancy
  • 32.  Temporary abstinence, also called the rhythm method or natural family planning, depends on refraining from intercourse during the days around ovulation, when fertilization is most likely.  Oral contraceptives, or birth control pills, come in several different forms that contain synthetic estrogen and/or progesterone (or a synthetic progesterone- like hormone called progestin).
  • 33. What is the fundamental difference between barrier methods (such as condoms) and oral contraceptives in terms of their means of preventing pregnancies? Barrier methods prevent sperm from reaching an egg, while birth control pills prevent the release of eggs altogether.
  • 34.  Pregnancy, or gestation - is the carrying of developing young within the female reproductive tract.  Human pregnancy averages 266 days (38 weeks) from fertilization (also called conception in humans), or 40 weeks (9 months) from the start of the last menstrual cycle.
  • 35.
  • 36.
  • 37. Affects the Embryo: 1. German measles virus- can cause serious birth defects 2. HIV- HIV-infected babies usually die of AIDS within a few years without treatment. 3. Alcohol and the chemicals in tobacco smoke, for instance, raise the risk of miscarriage and birth defects. 4. Alcohol can cause a set of birth defects called fetal alcohol syndrome, which includes mental retardation.
  • 41. Certain drugs cause their most serious damage to an embryo very early in pregnancy, often before the mother even realizes she is pregnant. Why? Because organ systems, such as circulatory and nervous systems, begin to develop in the first trimester.
  • 42.  The series of events that expel an infant from the uterus is called labor.  Estrogen- trigger the formation of numerous oxytocin receptors on cells of the uterus.  Oxytocin- stimulates the smooth muscles in the wall of the uterus, producing the series of increasingly strong, rhythmic contractions characteristic of labor.  Prostaglandins, local tissue regulators that stimulate the uterine muscle cells to contract even more.
  • 43. The induction of labor involves positive feedback, a type of control in which a change triggers mechanisms that amplify that change.
  • 44.  The first stage, dilation, is the time from the onset of labor until the cervix reaches its full dilation of about 10 cm. Dilation is the longest stage of labor, lasting 6–12 hours or even considerably longer.
  • 45.  Expulsion stage. Strong uterine contractions, lasting about 1 minute each, occur every 2– 3 minutes, and the mother feels an increasing urge to push or bear down with her abdominal muscles.
  • 46.  Delivery of the placenta. (“afterbirth”), usually within 15 minutes after the birth of the baby.  Prolactin and oxytocin promote milk production and release (called lactation) by the mammary glands.
  • 47. Reproductive technologies increase our reproductive options  About 15% of couples who want children are unable to conceive, even after 12 months of unprotected intercourse. Such a condition, called infertility, can have many causes.  Infertility is caused by impotence, also called erectile dysfunction, the inability to maintain an erection.
  • 48. Reproductive technologies increase our reproductive options  Female infertility can result from a lack of eggs, a failure to ovulate, or blocked oviducts (often caused by scarring due to sexually transmitted diseases).  Other women are able to conceive, but cannot support a growing embryo in the uterus. The resulting multiple miscarriages can take a heavy emotional toll.
  • 49.  Drug therapies (including Viagra) and penile implants can be used to treat impotence.  If a woman has normal eggs that are not being released properly, hormone injections can induce ovulation.  If a woman produces eggs but is unable to support a growing fetus, she and her partner may hire a surrogate mother.
  • 50.  Many infertile couples turn to fertilization procedures called assisted reproductive technologies.  In vitro fertilization (IVF), the most common assisted reproductive technology procedure, a woman’s eggs are mixed with sperm in culture dishes (in vitro means “in glass”) and incubated for several days to allow fertilized eggs to start developing.

Editor's Notes

  1. The uterus is the normal site of pregnancy. However, in about 1% of pregnancies, the embryo implants somewhere else, resulting in an ectopic pregnancy. Most ectopic pregnancies occur in the oviduct and are called tubal pregnancies.
  2. features of female reproductive anatomy in Figure 27.3C, a side view.
  3. Reproductive anatomy of the human male.
  4. Sperm cannot develop optimally at human core body temperature; the scrotum keeps the sperm-forming cells about 2°C cooler, which allows them to function normally. In cold conditions, muscles around the scrotum contract, pulling the testes toward the body, thereby maintaining the proper temperature.
  5. the path of sperm from one of the testes out of the male’s body.
  6. Fertilization occurs in the oviduct (Figure 27.15A). Cleavage starts about 24 hours after fertilization and continues as the embryo moves down the oviduct toward the uterus. 2. By the 6th or 7th day after fertilization, the embryo has reached the uterus, and cleavage has produced about 100 cells.
  7. The mother’s blood and the embryo’s blood are not in direct contact. Instead, the chorionic villi absorb nutrients and oxygen from the mother’s blood and pass these substances to the embryo via the chorionic blood vessels (that are shown in red). The chorionic vessels shown in blue carry wastes away from the embryo. The wastes diffuse into the mother’s bloodstream and are excreted by her kidneys.
  8. Figure 27.16B shows a developing human, now called a fetus, about 9 weeks after fertilization. The large pinkish structure on the left is the placenta, attached to the fetus by the umbilical cord. It is about 5.5 cm (2.2 inches) long. The limb buds have become tiny arms and legs with fingers and toes.
  9. Figure 27.16C shows a fetus at 14 weeks, 2 weeks into the second trimester. The fetus is now about 6 cm (2.4 inches) long. the placenta takes over the task of maintaining itself by secreting progesterone. At 20 weeks (Figure 27.16D), the fetus is about 19 cm (7.6 inches) long, weighs about half a kilogram (1 pound), and has the face of an infant, complete with eyebrows and eyelashes. Its arms, legs, fingers, and toes have lengthened. It also has fingernails and toenails and is covered with fine hair.
  10. The third trimester (28 weeks to birth) is a time of rapid growth as the fetus gains the strength it will need to survive outside the protective environment of the uterus. (Figure 27.16E), babies average about 50 cm (20 inches) in length and weigh 3–4 kg (6–8 pounds).
  11. Several hormones play key roles in this process (Figure 27.17A).
  12. The result is a steady increase in contraction intensity, climaxing in forceful muscle contractions that propel a baby from the uterus.
  13. Figure 27.17B shows the three stages of labor. As the process begins, the cervix (neck of the uterus) gradually opens, or dilates.
  14. The period from full dilation of the cervix to delivery of the infant is called the expulsion stage.
  15. After 2–3 days, the production of regular milk begins.