Subcutaneous mycoses

8,728 views

Published on

Published in: Business, Technology
1 Comment
8 Likes
Statistics
Notes
No Downloads
Views
Total views
8,728
On SlideShare
0
From Embeds
0
Number of Embeds
12
Actions
Shares
0
Downloads
268
Comments
1
Likes
8
Embeds 0
No embeds

No notes for slide

Subcutaneous mycoses

  1. 1. SUBCUTANEOUS MYCOSES grow on soil or on decaying vegetation must be introduced into subcutaneous tissue in order to produce disease GENERALLY : lesions spread slowly from the area of implantation extension via lymphatics draining the lesion is slow (except in sporotrichosis)Thursday, January 19, 2012
  2. 2. SPOROTHRIX SCHENCKII dimorphic live on plants or wood causes sporotrichosis chronic granulomatous infectionThursday, January 19, 2012
  3. 3. SPOROTHRIX SCHENCKII DIAGNOSTICS: pus or biopsy from lesions as specimens culture on Saboraud’s with clusters of conidia = diagnostic converts to yeast form at 37C agglutination of yeast cell from sera = not diagnosticThursday, January 19, 2012
  4. 4. SPOROTHRIX SCHENCKII TREATMENT: self-limited though chronic potassium iodide administered orally for weeks ampothericin B intravenously oral ketoconazoleThursday, January 19, 2012
  5. 5. CHROMOBLASTOMYCOSIS (Chomomycosis) slowly progressive granulomatous infection of skin caused by black molds Phialophora verrucosa, Fonsecaea pedrosoi, Rhinocladiella aquaspersa, Cladosporium carrioniiThursday, January 19, 2012
  6. 6. Phialophora verrucosaThursday, January 19, 2012
  7. 7. Fonsecaea pedrosoiThursday, January 19, 2012
  8. 8. Rhinocladiella aquaspersaThursday, January 19, 2012
  9. 9. Cladosporium carrioniiThursday, January 19, 2012
  10. 10. CHROMOBLASTOMYCOSIS (Chomomycosis) DIAGNOSTICS: specimen: scrapings or biopsy from lesions microscopy: scrapings in 10% potassium hydroxide (dark, round fungus cells = sclerotic bodies diagnostic) culture in Saboraud’s and digests gelatinThursday, January 19, 2012
  11. 11. CHROMOBLASTOMYCOSIS (Chomomycosis) TREATMENT: surgical excision with wide margins for small lesions chemotherapy with flucytosine or itraconazole for larger lesions locally applied heat may be beneficial relapse commonThursday, January 19, 2012

×