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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 5 Issue 6, September-October 2021 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1663
Theory of David Wartinger and Acharya
Charaka in the Management of Renal Calculi
Dr. Manjunath BR1
, Dr. Syed Ather Fathima2
, Dr. Shivalingappa J Arakeri3
,
Dr. Mohasin Kadegaon4
, Dr. Geetanjali Hiremath4
1
PG Scholar, 2
Principal, 3
Professor and HOD, 4
Assistant Professor,
1,3,4
Department of Shalya Tantra, Taranath Governament Ayurvedic Medical College, Ballari, Karnataka, India
2
Taranath Government Ayurvedic Medical College, Ballari, Karnataka, India
ABSTRACT
Ashmari is one of the most prevalent disease affecting the mutrvaha
srotas, Ashma means stone and ari means enemy,acharya Sushruta
has included under one among the ashtamahagada i.e difficult to
cure, as basti comes under trimarma Sushruta described ashmari as
daruna vyadhi. Acharya Charaka (2nd BC) approached special way
for removal of renal stones, He mentioned that riding the Horse,
Chariaot after drinking Madhya helps in passage of the Renal stones.
Last year David wartinger awarded ig Nobel prize in medicine for
discovering that ride on roller coaster can help hasten the passage of
kidney stones by preparing pyelocalyceal renal model (silicon)
validated ureteroscopy surgical simulator.
KEYWORDS: Ashmari, Renal stones, Rollercoaster, pyelocalyceal
renal model and ureteroscopy
How to cite this paper: Dr. Manjunath
BR | Dr. Syed Ather Fathima | Dr.
Shivalingappa J. Arakeri | Dr. Mohasin
Kadegaon | Dr. Geethanjali Hiremath
"Theory of David Wartinger and
Acharya Charaka in the Management of
Renal Calculi" Published in
International
Journal of Trend in
Scientific Research
and Development
(ijtsrd), ISSN: 2456-
6470, Volume-5 |
Issue-6, October
2021, pp.1663-
1666, URL:
www.ijtsrd.com/papers/ijtsrd47699.pdf
Copyright © 2021 by author (s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an
Open Access article
distributed under the
terms of the Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/by/4.0)
INTRODUCTION
Ashmari is one of the most prevalent disease affecting
the mutrvaha srotas, Ashma means stone and ari
means enemy, Ashmari has described in all the
Ayurvedic samhitas, but acharya Sushruta has
included under one among the ashtamahagada1
i.e
difficult to cure, as basti comes under trimarma2
Sushruta described ashmari as daruna vyadhi3
.
Ashmari is co-related with urolithiasis,the third most
common urinary tract disease exceeding UTI and
BPH alone. The prevelance is increasing due to
environmental cause and genetic predisposition. On
an average 6% woman and 12% men are affected
with renal stones. Recurrence rate of nephrolithiasis is
70-80%in males and 47-67% in females with majority
80% of calcium oxalate stones4-5
.
According to Ayurveda ashmari in the early stages is
treatable by medical management which mainly
includes ghrita, kshara, kashaya, ksheera, uttarabasti6
.
Here drugs which are having bhedana, mutrala
properties are used. but in chronic advanced cases
surgery is needed, The basic line of treatment for
urolithiasis in contemporory science is NSAID’S,
antispasmodic and hydration followed by diuretics so
if the size of the stone is small it easily comes out
through urine, if the size is large then ESWL is the
surgical interventions but post surgical complications
are quite common.
Acharya Charaka7
(2nd
BC) approached special way
for removal of renal stones, He mentioned that riding
the Horse, Chariaot after drinking Madhya helps in
passage of the Renal stones. Last year David
wartinger awarded ig Nobel prize in medicine for
discovering that ride on roller coaster can help hasten
the passage of kidney stones.
IJTSRD47699
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1664
AYURVEDIC METHOD:
Ayurveda classical texts like Charaka samhita,
Ashtanga hridaya stated that patient of ashmari is to
take shuddha madhya as madhya is having the
property of bhedana, srushta vinmutra, basti shodana.
And then made them to sit in chariot or on the horse
and go for ride, because of vibration the stone will
discend down from kidney to bladder and helps in
easily evacuation of the stones through urine.
Figure 1
Figure 2
METHEOD FROM CONTEMPORARY
SCIENCE:
Figure3 Validated ureteroscopy and renoscopy
surgical simulator
Figure4 Functional pyelocalyceal renal model
(silicon) modified from a validated ureteroscopy
and renoscopy surgical simulator
A high-fidelity adult ureteroscopy and renoscopy
simulator (Ideal Anatomic) was modified and
evaluated as a potential patient surrogate to study
variables associated with renal calculi passage8
(figure
1). The behavior of the renal calculi within the
pyelocalyceal renal model mimicked the clinical
experience and outcomes as reported by patients
anecdotally as well as according to the physiologic
behavior of renal calculi in the calices. The simulator
was adapted by remolding it in clear silicone to create
a functional pyelocalyceal renal model able to permit
direct inspection of calculi movement within the
calyceal system (Figure 2). The ureter and partial
bladder components of the Ideal Anatomic simulator
were removed during the modification process to
facilitate sealing the hollow portion of the renal
component. The sealed model contained 3 calcium
oxalate calculi with volumes of 4.5 mm, 13.5 mm, or
64.6 mm suspended in urine. The renal calculi used in
this study had been spontaneously passed from the
patient whose computed tomographic urogram scan
was used to create the original pyelocalyceal renal
cast model.
The roller coaster had twin tubular steel rails and it
did not go upside-down. The maximum speed was
35mph, and the model was subjected to sharp turn
and quick drops during the ride, which lasted 2
minutes and 30 seconds. The roller coaster was made
up of a railway train engine with no passenger seating
and 5 passanger cars with 3rows of seats and 2 to 3
passengers abreast in each car. While riding on the
roller coaster, the pyelocalyceal renal model was
seaated in an anatomic position inside a padded
backpack held against the back of the seat at renal
height betwen the researchers.
The renal calculi were loaded into the calyceal system
of the clear functional pyelocalyceal renal model and
their positions were documented. After each ride, the
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1665
position of each stone was recorded and renal calculi
were repositioned as needed. The renal calculi were
positioned into their calyceal locations using rotation,
external compression of the functional pyelocalyceal
renal model, and direct percutaneous needle
manipulation.
A renal calculus was recorded as passed if it moved
from a starting location in a renal calyx into the trap
at the level of the ureteropelvic junction. The
pyelocalyceal renal model containing 3 calculi was
taken for 20 rides on the roller coaster during the
2008 amusement park season. Seat assignment on the
roller coaster was random and determined as a
function of place in the waiting line. Stone
distribution within the model was allocated so a renal
calculus occupied each calyx during the trial. Care
was taken to protect and preserve the enjoyment of
the other guests at the park. Before the park's Guest
Services consented to our research project,
researchers agreed to abide by the park's tenets of
safety, show, courtesy, and efficiency
Table 1 Passage of renal calculi in a functional pyelocalyceal Renal model placed in front section of
roller coaster
Calculi volume
¯ Location of calculi in calyx 4.5mm3
13.5mm3
64.6mm3
Overall passage
Upper 0/1(0) 0/1(0) 2/7(28.6) 2/9(22.2)
Middle 0/4(0) 1/2(50.0) … 1/6(16.7)
Lower 1/3(33.3) 0/5(0) 0/1(0) 1/9(11.1)
Total 1/8(12.5) 1/8(12.5) 2/8(25.0) 4/24(16.7)
* Data are given as No.passed/No. Of attempts(%)
Table 2 Passage of renal calculi in a functional pyelocalyceal Renal model placed in rear section of
roller coaster
Calculi volume
¯ Location of calculi in calyx 4.5mm3
13.5mm3
64.6mm3
Overall passage
Upper 4/4(100) 4/4(100) 4/4(100) 12/12(100)
Middle 3/3(100) 1/4(25.0) 1/2(50.0) 5/9(55.6)
Lower 1/5(20.0) 2/4(50.0) 3/6(50.0) 6/15(40.0)
Total 8/12(66.7) 7/12(58.3) 8/12(66.7) 23/36(63.9)
* Data are given as No.passed/No. Of attempts(%)
DISCUSSION:
Many people experienced within a few hours drive of
an amusement park containing roller coaster with
features capable of dislodging calyceal renal calculi.
This made the group of reserchers in michigan state
university to prepare tghe ideal anatomic
ureteroscopy and renoscopy surgical simulator was
succecfully modifiedfor use as a patient surrogate in
the study of factors responsible renal calculi passage.
The pyelocalcyceal renal model was sensitive to
changes in its location on the roller coaster due to its
sharp turns and quick drops during the ride,
manifested with differential renal calculi passage and
awarded ig Nobel prize.
In our ancient indian classicals texts like Charaka
samhita and Ashtanga Hridaya has dealt similar
concept for dislodgement of the renal calculi by
riding on horse or chariaot after taking the shuddha
madhya due to sudden jurkey movements make the
dislodgment of the stones.
CONCLUSION:
As contemporory science developed the functional
pyelocalyceal renal model serves as a functional
patient to evaluate activities that facilitate calyceal
renal calculi passage in the roller coaster ride is
similar to that of riding on the horse or chariaot as
told by our classical texts.
REFERENCES:
[1] Sushruta, sushruta samhita dalhana
commentary nibandasangraha. Chaukamba
orientalia, varanasi. sutrasthana 33 chapter,
verse4-5.
[2] Acharya charaka, charaka samhita, chaukamba
orientalia, varanasi. chiktsasthana 26/3.
[3] Sushruta, sushruta samhita dalhana
commentary nibandasangraha. Chaukamba
orientalia, varanasi. chiktsasthana 7 chapter,
verse3.
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1666
[4] Butterweck, V. and S. R. Khan, 2009. Herbal
medicines in the management of urolithiasis:
Alternative or complementary? Planta Med.,
75: 1095-1103.
[5] Cao, L. C., J. A. Jonassen, T. W. Honeyman
and C. Scheid, 2001. Oxalate-induced
redistribution of phosphatidylserine in renal
epithelial cells: Implications for kidney stone
disease. Am. J. Nephrol., 21: 69-77.
[6] Sushruta, sushruta samhita dalhana
commentary nibandasangraha. Chaukamba
orientalia, varanasi. chiktsasthana 7 chapter,
verse27.
[7] Acharya charaka, charaka samhita, chaukamba
orientalia, varanasi. chiktsasthana 26/57.
[8] MitchellMA, WartingerDD. Validation of a
functional pyelocalyceal renal model for the
evaluation of renal calculi passage while riding
a roller coaster. J Am Osteopath Assoc. 2016;
116(10):647-652. doi:10.7556/jaoa.2016.128
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Theory of David Wartinger and Acharya Charaka in the Management of Renal Calculi

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 5 Issue 6, September-October 2021 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1663 Theory of David Wartinger and Acharya Charaka in the Management of Renal Calculi Dr. Manjunath BR1 , Dr. Syed Ather Fathima2 , Dr. Shivalingappa J Arakeri3 , Dr. Mohasin Kadegaon4 , Dr. Geetanjali Hiremath4 1 PG Scholar, 2 Principal, 3 Professor and HOD, 4 Assistant Professor, 1,3,4 Department of Shalya Tantra, Taranath Governament Ayurvedic Medical College, Ballari, Karnataka, India 2 Taranath Government Ayurvedic Medical College, Ballari, Karnataka, India ABSTRACT Ashmari is one of the most prevalent disease affecting the mutrvaha srotas, Ashma means stone and ari means enemy,acharya Sushruta has included under one among the ashtamahagada i.e difficult to cure, as basti comes under trimarma Sushruta described ashmari as daruna vyadhi. Acharya Charaka (2nd BC) approached special way for removal of renal stones, He mentioned that riding the Horse, Chariaot after drinking Madhya helps in passage of the Renal stones. Last year David wartinger awarded ig Nobel prize in medicine for discovering that ride on roller coaster can help hasten the passage of kidney stones by preparing pyelocalyceal renal model (silicon) validated ureteroscopy surgical simulator. KEYWORDS: Ashmari, Renal stones, Rollercoaster, pyelocalyceal renal model and ureteroscopy How to cite this paper: Dr. Manjunath BR | Dr. Syed Ather Fathima | Dr. Shivalingappa J. Arakeri | Dr. Mohasin Kadegaon | Dr. Geethanjali Hiremath "Theory of David Wartinger and Acharya Charaka in the Management of Renal Calculi" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456- 6470, Volume-5 | Issue-6, October 2021, pp.1663- 1666, URL: www.ijtsrd.com/papers/ijtsrd47699.pdf Copyright © 2021 by author (s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0) INTRODUCTION Ashmari is one of the most prevalent disease affecting the mutrvaha srotas, Ashma means stone and ari means enemy, Ashmari has described in all the Ayurvedic samhitas, but acharya Sushruta has included under one among the ashtamahagada1 i.e difficult to cure, as basti comes under trimarma2 Sushruta described ashmari as daruna vyadhi3 . Ashmari is co-related with urolithiasis,the third most common urinary tract disease exceeding UTI and BPH alone. The prevelance is increasing due to environmental cause and genetic predisposition. On an average 6% woman and 12% men are affected with renal stones. Recurrence rate of nephrolithiasis is 70-80%in males and 47-67% in females with majority 80% of calcium oxalate stones4-5 . According to Ayurveda ashmari in the early stages is treatable by medical management which mainly includes ghrita, kshara, kashaya, ksheera, uttarabasti6 . Here drugs which are having bhedana, mutrala properties are used. but in chronic advanced cases surgery is needed, The basic line of treatment for urolithiasis in contemporory science is NSAID’S, antispasmodic and hydration followed by diuretics so if the size of the stone is small it easily comes out through urine, if the size is large then ESWL is the surgical interventions but post surgical complications are quite common. Acharya Charaka7 (2nd BC) approached special way for removal of renal stones, He mentioned that riding the Horse, Chariaot after drinking Madhya helps in passage of the Renal stones. Last year David wartinger awarded ig Nobel prize in medicine for discovering that ride on roller coaster can help hasten the passage of kidney stones. IJTSRD47699
  • 2. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1664 AYURVEDIC METHOD: Ayurveda classical texts like Charaka samhita, Ashtanga hridaya stated that patient of ashmari is to take shuddha madhya as madhya is having the property of bhedana, srushta vinmutra, basti shodana. And then made them to sit in chariot or on the horse and go for ride, because of vibration the stone will discend down from kidney to bladder and helps in easily evacuation of the stones through urine. Figure 1 Figure 2 METHEOD FROM CONTEMPORARY SCIENCE: Figure3 Validated ureteroscopy and renoscopy surgical simulator Figure4 Functional pyelocalyceal renal model (silicon) modified from a validated ureteroscopy and renoscopy surgical simulator A high-fidelity adult ureteroscopy and renoscopy simulator (Ideal Anatomic) was modified and evaluated as a potential patient surrogate to study variables associated with renal calculi passage8 (figure 1). The behavior of the renal calculi within the pyelocalyceal renal model mimicked the clinical experience and outcomes as reported by patients anecdotally as well as according to the physiologic behavior of renal calculi in the calices. The simulator was adapted by remolding it in clear silicone to create a functional pyelocalyceal renal model able to permit direct inspection of calculi movement within the calyceal system (Figure 2). The ureter and partial bladder components of the Ideal Anatomic simulator were removed during the modification process to facilitate sealing the hollow portion of the renal component. The sealed model contained 3 calcium oxalate calculi with volumes of 4.5 mm, 13.5 mm, or 64.6 mm suspended in urine. The renal calculi used in this study had been spontaneously passed from the patient whose computed tomographic urogram scan was used to create the original pyelocalyceal renal cast model. The roller coaster had twin tubular steel rails and it did not go upside-down. The maximum speed was 35mph, and the model was subjected to sharp turn and quick drops during the ride, which lasted 2 minutes and 30 seconds. The roller coaster was made up of a railway train engine with no passenger seating and 5 passanger cars with 3rows of seats and 2 to 3 passengers abreast in each car. While riding on the roller coaster, the pyelocalyceal renal model was seaated in an anatomic position inside a padded backpack held against the back of the seat at renal height betwen the researchers. The renal calculi were loaded into the calyceal system of the clear functional pyelocalyceal renal model and their positions were documented. After each ride, the
  • 3. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1665 position of each stone was recorded and renal calculi were repositioned as needed. The renal calculi were positioned into their calyceal locations using rotation, external compression of the functional pyelocalyceal renal model, and direct percutaneous needle manipulation. A renal calculus was recorded as passed if it moved from a starting location in a renal calyx into the trap at the level of the ureteropelvic junction. The pyelocalyceal renal model containing 3 calculi was taken for 20 rides on the roller coaster during the 2008 amusement park season. Seat assignment on the roller coaster was random and determined as a function of place in the waiting line. Stone distribution within the model was allocated so a renal calculus occupied each calyx during the trial. Care was taken to protect and preserve the enjoyment of the other guests at the park. Before the park's Guest Services consented to our research project, researchers agreed to abide by the park's tenets of safety, show, courtesy, and efficiency Table 1 Passage of renal calculi in a functional pyelocalyceal Renal model placed in front section of roller coaster Calculi volume ¯ Location of calculi in calyx 4.5mm3 13.5mm3 64.6mm3 Overall passage Upper 0/1(0) 0/1(0) 2/7(28.6) 2/9(22.2) Middle 0/4(0) 1/2(50.0) … 1/6(16.7) Lower 1/3(33.3) 0/5(0) 0/1(0) 1/9(11.1) Total 1/8(12.5) 1/8(12.5) 2/8(25.0) 4/24(16.7) * Data are given as No.passed/No. Of attempts(%) Table 2 Passage of renal calculi in a functional pyelocalyceal Renal model placed in rear section of roller coaster Calculi volume ¯ Location of calculi in calyx 4.5mm3 13.5mm3 64.6mm3 Overall passage Upper 4/4(100) 4/4(100) 4/4(100) 12/12(100) Middle 3/3(100) 1/4(25.0) 1/2(50.0) 5/9(55.6) Lower 1/5(20.0) 2/4(50.0) 3/6(50.0) 6/15(40.0) Total 8/12(66.7) 7/12(58.3) 8/12(66.7) 23/36(63.9) * Data are given as No.passed/No. Of attempts(%) DISCUSSION: Many people experienced within a few hours drive of an amusement park containing roller coaster with features capable of dislodging calyceal renal calculi. This made the group of reserchers in michigan state university to prepare tghe ideal anatomic ureteroscopy and renoscopy surgical simulator was succecfully modifiedfor use as a patient surrogate in the study of factors responsible renal calculi passage. The pyelocalcyceal renal model was sensitive to changes in its location on the roller coaster due to its sharp turns and quick drops during the ride, manifested with differential renal calculi passage and awarded ig Nobel prize. In our ancient indian classicals texts like Charaka samhita and Ashtanga Hridaya has dealt similar concept for dislodgement of the renal calculi by riding on horse or chariaot after taking the shuddha madhya due to sudden jurkey movements make the dislodgment of the stones. CONCLUSION: As contemporory science developed the functional pyelocalyceal renal model serves as a functional patient to evaluate activities that facilitate calyceal renal calculi passage in the roller coaster ride is similar to that of riding on the horse or chariaot as told by our classical texts. REFERENCES: [1] Sushruta, sushruta samhita dalhana commentary nibandasangraha. Chaukamba orientalia, varanasi. sutrasthana 33 chapter, verse4-5. [2] Acharya charaka, charaka samhita, chaukamba orientalia, varanasi. chiktsasthana 26/3. [3] Sushruta, sushruta samhita dalhana commentary nibandasangraha. Chaukamba orientalia, varanasi. chiktsasthana 7 chapter, verse3.
  • 4. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD47699 | Volume – 5 | Issue – 6 | Sep-Oct 2021 Page 1666 [4] Butterweck, V. and S. R. Khan, 2009. Herbal medicines in the management of urolithiasis: Alternative or complementary? Planta Med., 75: 1095-1103. [5] Cao, L. C., J. A. Jonassen, T. W. Honeyman and C. Scheid, 2001. Oxalate-induced redistribution of phosphatidylserine in renal epithelial cells: Implications for kidney stone disease. Am. J. Nephrol., 21: 69-77. [6] Sushruta, sushruta samhita dalhana commentary nibandasangraha. Chaukamba orientalia, varanasi. chiktsasthana 7 chapter, verse27. [7] Acharya charaka, charaka samhita, chaukamba orientalia, varanasi. chiktsasthana 26/57. [8] MitchellMA, WartingerDD. Validation of a functional pyelocalyceal renal model for the evaluation of renal calculi passage while riding a roller coaster. J Am Osteopath Assoc. 2016; 116(10):647-652. doi:10.7556/jaoa.2016.128 Search in Google Scholar