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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 4 Issue 5, August 2020 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 163
A Mathematical Analysis of Blood
Flow through Artery with Mild Stenosis
Karm Veer Singh1, Sushil Kumar2, Dr. A. K. Yadav3, C. S. Yadav3, Dr. S. S. Yadav4
1Research Scholar, Department of Mathematics, Dr. B.R.A. University, Agra, Uttar Pradesh, India
2Department of Mathematics, C.C.S. P.G. College, Heonra, Uttar Pradesh, India
3Department of Mathematics, Govt. P.G. College, Datia, Madhya Pradesh, India
4Department of Mathematics, N.D. P.G. College, Shikohabad, Uttar Pradesh, India
ABSTRACT
Presented herein are the studies of blood flow through artery with mild
stenosis. The parameter specified μ and R. It has been observed that the
increases the viscosity increase the load capacity. Again it has been
observed that increases the value of R decreases the load capacity.
KEYWORDS: artery, blood flow, biological fluid, load capacity, human skeletal
How to cite this paper: Karm Veer Singh
| Sushil Kumar | Dr. A. K. Yadav | C. S.
Yadav | Dr. S. S. Yadav "A Mathematical
Analysis of Blood Flow through Artery
with Mild Stenosis"
Published in
International
Journal of Trend in
Scientific Research
and Development
(ijtsrd), ISSN: 2456-
6470, Volume-4 |
Issue-5, August 2020, pp.163-165, URL:
www.ijtsrd.com/papers/ijtsrd31773.pdf
Copyright © 2020 by author(s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an Open Access article
distributed under
the terms of the
Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/
by/4.0)
INTRODUCTION
The term stenosis is the narrowing of the artery due the
development of arteriosclerotic plaques. The lumen of the
artery, blood flow is obstructed. The obstruction may
damage the interval cells of the wall and may lead to
further growth of the stenosis. Then there is a coupling
between the growth of the stenosis and the flow of blood
in the artery affect each other. The stenosis growth usually
passes. There is no separation of flow and there is no back
flow.
The development of stenosis is an artery can have serious
consequences. It may lead to increased resistance to flow,
with possible serve reduction in blood flow and increased
danger of complex occlusion. Abnormal cellular growth in
the viciniey of the stenosis, which increases the intensity
of the stenosis and damage tissues leading to post-stenosis
dilatation.
Blood has been taken homogeneous which obeys the
Newton’s law of friction. But this law hold goods if the flow
occurs in tubes in which internal diameter is large
compared with the size of the red cells. Most of the
biological fluid are in fact non-Newtonian. In a study of the
non-Newtonian behaviour of blood. It is observed that the
non-Newtonian fluid flow involves many new features.
However for most purposes blood can be treated
theoretically as an ordinary with an appropriate effective
viscosity coefficient.
Physiologist concerned the blood circulation problem of
wave propagation in a system of tube. The problem too
has been studied by various authors theoretically as well
experimentally1,2,3 Some investigator have studied the
problem. Biomechanics has attracted mathematicians,
engineering’s, and scientists to study the functioning
behavior of human skeletal system.
Various mathematician’s considered the problem of
lubrication of approaching porous surfaces in reference to
human joints9,10. Having discussed the structural
properties of the arterial, we now turn our attention to the
transport medium. Physiologically, amongst other function
blood serve as transportation of respiratory gases,
nutrients, waste products of metabolism etc. Blood is a
suspension of particles is an aqueous solution, it is not a
homogeneous fluid and has some unusual properties.
Blood flow problems are more complicated than the fluid
flow problems. The properties arise from fact that the
vessels walls are formed of different substances such as
IJTSRD31773
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 164
elastic, collagen and smooth mussels with entirely
different properties.
In this research paper we considered the steady flow of a
Newtonian fluid in a stenosis.
Formulation of the problem
The detail some of the model outputs will be performed.
This model is of relevance studies in particularly in the
real world. In this model considered the study flow of a
Newtonian fluid in a stenosis.
The Navier stokes equation;
−
𝜕𝑝
𝜕𝑟
= 0 (1)
and
0 = −
𝜕𝑝
𝜕𝑧
+ 𝜇 (
𝜕2 𝑉
𝜕𝑟2 +
1
𝑟
𝜕𝑉
𝜕𝑟
) (2)
Equation (2) can be written as
0 = −
𝜕𝑝
𝜕𝑧
+
𝜇
𝑟
𝜕
𝜕𝑟
(𝑟
𝜕𝑉
𝜕𝑟
) (3)
The no-slip condition on the stenosis,
Surface gives
𝑉 = 0 at 𝑟 = 𝑅
𝑉 = 0 at 𝑟 = 𝑅0 (4)
And
𝜕𝑉
𝜕𝑟
= 0 at 𝑟 = 0 (5)
Solution of the problem
Differentiating equation (3) partially w.r.to z, we get
−
𝜕2 𝑝
𝜕𝑧2 = 0 (6)
Integrating we get
−
𝜕𝑝
𝜕𝑧
= ∆𝑝 (7)
From equation (3) and (7), we get
𝜕
𝜕𝑟
(𝑟
𝜕𝑉
𝜕𝑟
) =
∆𝑝𝑟
𝜇
(8)
Integrating equation (8) and applying the boundary
condition, we get
𝑉 =
∆𝑝
4𝜇
(𝑟2
− 𝑅2) (9)
The volume flow rate is
𝑄 = ∫ 𝑉2𝜋𝑟𝑑𝑟
𝑅
0
=
𝜋∆𝑝
2𝜇
∫ (𝑟2
− 𝑅2)𝑟𝑑𝑟
𝑟
0
=
𝜋∆𝑝
8𝜇
𝑅4
(10)
But volume flow rate Q is constant for all section of tube,
then
∆𝑝 =
8𝜇𝑄
𝜋𝑅4 (11)
The load capacity is
𝑊 = ∫ ∆𝑝𝑑𝑟
𝑟
0
= (
8𝜇𝑄
𝜋𝑅3
) (12)
Result and Discussion
The present paper proposes a more realistic model for explaining the blood flow in a stenosis. The load capacity depends
on various values of parameter 𝜇 and R. It has been observed that the increases the viscosity increase the load capacity.
Again it has been observed that increases the value of R decrease the load capacity.
Values load capacity W for different values 𝝁 & R at Q= 1
𝝁
R
2 4 6 8 10
0.5 40.80 81.52 122.32 163.04 203.84
1.0 5.10 10.19 15.29 20.38 25.48
1.5 1.51 3.02 4.52 6.03 7.54
2.0 0.64 1.27 1.91 2.55 3.19
2.5 0.33 0.65 0.98 1.30 1.63
Variation of load capacity W for different values 𝝁 & R at Q= 1
0
50
100
150
200
250
0.5 1 1.5 2 2.5
μ=2
μ=4
μ=6
μ=8
μ=10
W
R
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 165
Reference
[1] Downson, D. (1967) Model of lubrication an human
Joints Proc. Inst. Mech. Engrs. 183(3).
[2] Mow, C. W. (1968) the role of lubrication of
Biomechanical joints J. Iubr. Tech.91,320
[3] Ogston, A. G. and J. E. Stanier (1953) Viscous elastic
lubricant properties Physiol. 119, p244-252
[4] Tandon, P. N. and S. Jaggi (1977) Lubrication of
Hertzian contacts in reference to human joints. Med.
Life Sci. Eng. 3(7)
[5] Tandon, P. N. and S. Jaggi (1977) Lubrication of
porous solid in reference to human joints Pro. Ind.
Acad. Sci. Sect. A85, 144.
[6] Yadav A. K. and Pokhriyal S. C. (2000): synovial fluid
flow in reference to human joints. Ind. J. Appl. Sci.
Periodical vol. 2, p 104-110.
[7] Yadav, A. K. (2000) Synovial fluid behavior in
reference to animal joints. Indian Jr. Pure and Apple.
Sci. Vol. 19(E), 311-316
[8] Yadav A. K and Kumar S. (2016): Synovial fluid flow
in reference to animal joints. Intr. Jr. Stream
Research Vol. 6 issu-12, p-1-5.
[9] Yadav A. K. and Kumar S. (2016): Mathematical
analysis for the lubrication mechanism of knee joints.
Intr. Jr. of orthopaedics Photon. Vol.11, p 120-122.
[10] Yadav A.K. and Kumar S. (2020): Behaviour of
synovial fluid in a channel. IJCRT Vol. 8 issu.- 3 p
2823-2833.

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A Mathematical Analysis of Blood Flow through Artery with Mild Stenosis

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 4 Issue 5, August 2020 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 163 A Mathematical Analysis of Blood Flow through Artery with Mild Stenosis Karm Veer Singh1, Sushil Kumar2, Dr. A. K. Yadav3, C. S. Yadav3, Dr. S. S. Yadav4 1Research Scholar, Department of Mathematics, Dr. B.R.A. University, Agra, Uttar Pradesh, India 2Department of Mathematics, C.C.S. P.G. College, Heonra, Uttar Pradesh, India 3Department of Mathematics, Govt. P.G. College, Datia, Madhya Pradesh, India 4Department of Mathematics, N.D. P.G. College, Shikohabad, Uttar Pradesh, India ABSTRACT Presented herein are the studies of blood flow through artery with mild stenosis. The parameter specified μ and R. It has been observed that the increases the viscosity increase the load capacity. Again it has been observed that increases the value of R decreases the load capacity. KEYWORDS: artery, blood flow, biological fluid, load capacity, human skeletal How to cite this paper: Karm Veer Singh | Sushil Kumar | Dr. A. K. Yadav | C. S. Yadav | Dr. S. S. Yadav "A Mathematical Analysis of Blood Flow through Artery with Mild Stenosis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456- 6470, Volume-4 | Issue-5, August 2020, pp.163-165, URL: www.ijtsrd.com/papers/ijtsrd31773.pdf Copyright © 2020 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/ by/4.0) INTRODUCTION The term stenosis is the narrowing of the artery due the development of arteriosclerotic plaques. The lumen of the artery, blood flow is obstructed. The obstruction may damage the interval cells of the wall and may lead to further growth of the stenosis. Then there is a coupling between the growth of the stenosis and the flow of blood in the artery affect each other. The stenosis growth usually passes. There is no separation of flow and there is no back flow. The development of stenosis is an artery can have serious consequences. It may lead to increased resistance to flow, with possible serve reduction in blood flow and increased danger of complex occlusion. Abnormal cellular growth in the viciniey of the stenosis, which increases the intensity of the stenosis and damage tissues leading to post-stenosis dilatation. Blood has been taken homogeneous which obeys the Newton’s law of friction. But this law hold goods if the flow occurs in tubes in which internal diameter is large compared with the size of the red cells. Most of the biological fluid are in fact non-Newtonian. In a study of the non-Newtonian behaviour of blood. It is observed that the non-Newtonian fluid flow involves many new features. However for most purposes blood can be treated theoretically as an ordinary with an appropriate effective viscosity coefficient. Physiologist concerned the blood circulation problem of wave propagation in a system of tube. The problem too has been studied by various authors theoretically as well experimentally1,2,3 Some investigator have studied the problem. Biomechanics has attracted mathematicians, engineering’s, and scientists to study the functioning behavior of human skeletal system. Various mathematician’s considered the problem of lubrication of approaching porous surfaces in reference to human joints9,10. Having discussed the structural properties of the arterial, we now turn our attention to the transport medium. Physiologically, amongst other function blood serve as transportation of respiratory gases, nutrients, waste products of metabolism etc. Blood is a suspension of particles is an aqueous solution, it is not a homogeneous fluid and has some unusual properties. Blood flow problems are more complicated than the fluid flow problems. The properties arise from fact that the vessels walls are formed of different substances such as IJTSRD31773
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 164 elastic, collagen and smooth mussels with entirely different properties. In this research paper we considered the steady flow of a Newtonian fluid in a stenosis. Formulation of the problem The detail some of the model outputs will be performed. This model is of relevance studies in particularly in the real world. In this model considered the study flow of a Newtonian fluid in a stenosis. The Navier stokes equation; − 𝜕𝑝 𝜕𝑟 = 0 (1) and 0 = − 𝜕𝑝 𝜕𝑧 + 𝜇 ( 𝜕2 𝑉 𝜕𝑟2 + 1 𝑟 𝜕𝑉 𝜕𝑟 ) (2) Equation (2) can be written as 0 = − 𝜕𝑝 𝜕𝑧 + 𝜇 𝑟 𝜕 𝜕𝑟 (𝑟 𝜕𝑉 𝜕𝑟 ) (3) The no-slip condition on the stenosis, Surface gives 𝑉 = 0 at 𝑟 = 𝑅 𝑉 = 0 at 𝑟 = 𝑅0 (4) And 𝜕𝑉 𝜕𝑟 = 0 at 𝑟 = 0 (5) Solution of the problem Differentiating equation (3) partially w.r.to z, we get − 𝜕2 𝑝 𝜕𝑧2 = 0 (6) Integrating we get − 𝜕𝑝 𝜕𝑧 = ∆𝑝 (7) From equation (3) and (7), we get 𝜕 𝜕𝑟 (𝑟 𝜕𝑉 𝜕𝑟 ) = ∆𝑝𝑟 𝜇 (8) Integrating equation (8) and applying the boundary condition, we get 𝑉 = ∆𝑝 4𝜇 (𝑟2 − 𝑅2) (9) The volume flow rate is 𝑄 = ∫ 𝑉2𝜋𝑟𝑑𝑟 𝑅 0 = 𝜋∆𝑝 2𝜇 ∫ (𝑟2 − 𝑅2)𝑟𝑑𝑟 𝑟 0 = 𝜋∆𝑝 8𝜇 𝑅4 (10) But volume flow rate Q is constant for all section of tube, then ∆𝑝 = 8𝜇𝑄 𝜋𝑅4 (11) The load capacity is 𝑊 = ∫ ∆𝑝𝑑𝑟 𝑟 0 = ( 8𝜇𝑄 𝜋𝑅3 ) (12) Result and Discussion The present paper proposes a more realistic model for explaining the blood flow in a stenosis. The load capacity depends on various values of parameter 𝜇 and R. It has been observed that the increases the viscosity increase the load capacity. Again it has been observed that increases the value of R decrease the load capacity. Values load capacity W for different values 𝝁 & R at Q= 1 𝝁 R 2 4 6 8 10 0.5 40.80 81.52 122.32 163.04 203.84 1.0 5.10 10.19 15.29 20.38 25.48 1.5 1.51 3.02 4.52 6.03 7.54 2.0 0.64 1.27 1.91 2.55 3.19 2.5 0.33 0.65 0.98 1.30 1.63 Variation of load capacity W for different values 𝝁 & R at Q= 1 0 50 100 150 200 250 0.5 1 1.5 2 2.5 μ=2 μ=4 μ=6 μ=8 μ=10 W R
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD31773 | Volume – 4 | Issue – 5 | July-August 2020 Page 165 Reference [1] Downson, D. (1967) Model of lubrication an human Joints Proc. Inst. Mech. Engrs. 183(3). [2] Mow, C. W. (1968) the role of lubrication of Biomechanical joints J. Iubr. Tech.91,320 [3] Ogston, A. G. and J. E. Stanier (1953) Viscous elastic lubricant properties Physiol. 119, p244-252 [4] Tandon, P. N. and S. Jaggi (1977) Lubrication of Hertzian contacts in reference to human joints. Med. Life Sci. Eng. 3(7) [5] Tandon, P. N. and S. Jaggi (1977) Lubrication of porous solid in reference to human joints Pro. Ind. Acad. Sci. Sect. A85, 144. [6] Yadav A. K. and Pokhriyal S. C. (2000): synovial fluid flow in reference to human joints. Ind. J. Appl. Sci. Periodical vol. 2, p 104-110. [7] Yadav, A. K. (2000) Synovial fluid behavior in reference to animal joints. Indian Jr. Pure and Apple. Sci. Vol. 19(E), 311-316 [8] Yadav A. K and Kumar S. (2016): Synovial fluid flow in reference to animal joints. Intr. Jr. Stream Research Vol. 6 issu-12, p-1-5. [9] Yadav A. K. and Kumar S. (2016): Mathematical analysis for the lubrication mechanism of knee joints. Intr. Jr. of orthopaedics Photon. Vol.11, p 120-122. [10] Yadav A.K. and Kumar S. (2020): Behaviour of synovial fluid in a channel. IJCRT Vol. 8 issu.- 3 p 2823-2833.