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Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 34 | P a g e
A Stochastic Model by the Fourier Transform of Pde for the Glp -
1
Dr. P. Senthilkumar** and D. Sargunasundari*
** Assistant Professor, Department of Mathematics, Rajah Serfoji Government College, Thanjavur, India.
* Assistant Professor, Department of Mathematics, Bharath College of Science & Management, Thanjavur,
India.
Abstract
The peptide hormone glucagon like peptide GLP -1 has most important actions resulting in glucose lowering
along with weight loss in patients with type 2 diabetes. As a peptide hormone, GLP -1 has to be administered by
injection. A few small-molecule agonists to peptide hormone receptors have been described.
Here we develop a model for credit risk based on a model with stochastic eigen values called principal
component stochastic covariance. The fourier transform of the Green function of the pricing PDE is,



 




ekk
e
kB
)1()1(
1
.),(
Keywords: GLP- 1, stochastic models, wishart process, stochastic covariance.
2000 Mathematics subject Classification: 60 H15
I. INTRODUCTION
GLP-1 is one of the incretine, is a natural postprandial hormone released in response to nutrient intake and
acts to stimulate insulin secretion. GLP -1 has attracted much interest as a future treatment for type -2 diabetes
because it has multiple antidiabetic actions and at the same time, lowers body weight. The compounds were not
antagonized by the selective GLP-1 receptor antagonist, exendin. Exendin is a fragment of a close analog of
GLP-1 and must be expected to bind at the orthosteric agonist binding site.
The mechanism behind the phenomenon was investigated further in a saturation binding experiment
measuring the affinity and number of binding sites for GLP-1 in the absence or presence of compound 2.
II. NOTATIONS
Di  Symmetric positive definite matrix
Wi  Brownian motion
r(t)  Risk free interest rate
di(t)  Dividend yield for the ith
firm
Tr  Trace of a matrix
i  Stopping time
)(|| ti   Truncating factor
III. THE CREDIT GRADES WISHART PROCESS:
In Credit Grades model, we assumes that volatility is deterministic. By means of stochastic covariance
wishart process, we extend credit grades model. A wishart process with integer degree of freedom k is a sum of
k independent n-dimensional Ornstein –uhlenbeck process.
Consider  k
k
k
V 1 as an independent set of Ornstein – Uhlenbeck process.
)()()( k
t
k
t
k
t RdWdtBVdV 
Where B and R are (n,n ) matrices with R invertible[1,2].
Then a wishart process of degree k is defined as
RESEARCH ARTICLE OPEN ACCESS
Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 35 | P a g e


k
k
k
t
k
tt VVY
1
)'()(
,
Where
)(k
tV is the transpose of the Vector
)(k
tV .
Here By using a Ito’s lemma, to find a diffusion SDE for the process tY
 

)(
1
)'()()'()()'()(
..
kK
k
k
t
k
t
k
t
k
t
k
t
k
tt dVdVdVVVdVdY
=  

k
k
k
t
k
t
k
t
k
ttt RdWVVRdWdtBYBYRKR
1
')'()()'()(''
)(
Here the term of the SDE contains tY , but the diffusion part contains the terms
)(k
tV and
)'(k
tV . Also
tY satisfies the following matrix SDE.,[3]
  '2
1
2
1''
RdWYYRdWdtBYBYRKRdY ttttttt  , …….(1)
Where tW is an n x n standard Brownian motion matrix.
IV. THE DYNAMICS OF THE ASSETS :
The assets are defined on a probability space ),,( RF Where   0ttF is the information up to time t
and R is the risk – natural measure equivalent to the measure P.
Let us assume that the ith
firm’s asset price per share is given by Ai(t).
Here we review the results regarding the dynamics of the assets with stochastic covariance wishart process.
Assume the asset’s prices follow the multivariate real – world model,
  A
tttiit dWYdtYDTrAd 2
1
))((ln  
'2
1
2
1'
qdwYYMYMYdY tttttt


'2
1'
)'( RdwYRdWdtMYMYdY ttttt 

 ……(2)
Here the vector  n ...............1 is constant and Di is a symmetric positive definite matrix, the log
price process has the drift term,
     dtYDTAdE tiitt ln   and the Quadratic variation dtYAdV ttt )ln(
Also we assume that the Brownian motion driving the assets and the Brownian motions driving the wishart
proves are uncorrelated.
  0tiYDTr accounts for risk premium. For the transition distribution of At+h given At and  tY We have
  ,,ln~)(,/ln 







 


ht
t
u
ht
t
uitttht duYduYDTrANYAA 
and the unconditional probability function can be found by Integration over the distribution function of

ht
t
u duY
Now that we have identified the dynamics of the assets, we explain the mechanism of the Credit Grades
model, As before, we assume that the ith firm’s value At(t) is driven by the dynamics






ttttttt
ttiii
YRRdZYdtMYMYdY
dWYIdttdtrtAdiagtdA
"
)''(
]))()())[(()(
……. (3)
Where =RR for some >n-1 and M is a negative definite matrix.
Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 36 | P a g e
V. EQUITY CALL OPTIONS
The price of a European call option on the equity is calculated by discounting the risk – neutral expectation
of the payoff at maturity.
Since       TTiTnTi ii
KSKS 

  |||| ,, the price of the call option could be rewritten as Vcall (t,
Y, Si, k)
=   

















 KSdssrE TTi
T
t
Q
SYt ii ||)(exp ,),,(
=
















 

 TTi
T
t
Q
SYt ii
KSdssrE ||)()(exp ,),,(
The price of a single name derivative on one of the equities satisfies the partial differential
equation[4,5].
Ut + ),( iSYA – rU = 0
Here the price of an equity call option is given by the PDE is
    0)()()(
2
1 2
 rUUAVStdtrUtDSYU YsiiSSiiiit iii
…… (4)
U(t,0) = 0, U(T,S) = (S-k)+
,
where A(Y,S) is the infinitesimal generator of the joint process (S, Y) .
We first joint change the variable by





 

)(
)(
ln
tD
tDS
x
i
ii
i 




 

)(
)(
ln
tD
ktD
a
i
i
i and
G(t,xi) = exp ( 
T
t
dssr )(
)(
),(
TD
StU
i
i
to transform the PDE to
 
   


aixi
i
Yiiiiit
eexTUtG
GAGxxGxYG
,,0)0,(
,0
2
1
…..(5)
The Fourier transform of the Green’s function of PDE is given by[6]
 
,),,(
),((,
dkeXYq
YkBTkAiky
j
rj






 …..(6)
Where,     kkkB ,),(),( 21
1
22  









 


0
),('),( dukuBRRTrkA
With 








2221
1211
















 '
4
1
2
1
'2
exp 2
MIk
RRM

Now that we have found the fourier transform of the Green’s function of the pricing PDE, we solve the
pricing problem for an equity call option by the method of images.
Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 37 | P a g e
VI. RESULT
The price of a call option on Sj(t) with maturity date T and strike price k is given by,
V(t,Sj)=   ),()(exp)( yZdssrKTD
T
t








 
y = ln(S+D(t)) - ln(D(t)+K)+  
T
t
dssdsr ))()((
b = ln(D(t)) - ln(D(t)+K)+  
T
t
dssdsr ))()((
and the function z is defined by

 


0
)),((),(
2
)))2cos(()(cos(
),( ds
kbyykee
eeyZ
YkBTkAy
by
r



….(7)
If in the dynamics of the asset (3), We assume n=1 and for the parameters
2
k
M  ,
2

R and k' , we have ),( kB  =
22
12


Now to find 12 and 22 , we have[8,9,10],













22
)
4
1
(
2
1
2
2
2
k
k
E


E
e
 is a 2 x2 matrix with




2
2
4
222
12
2
)(
),(












eek
k




2
222
22
2
)()((
),(




ekek
k
 22
 k
Therefore ),( kB  = e = 


 



ekk
e
)1()1(
1
…… (8)
Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 38 | P a g e
Fig. 1
Example
As per the data the saturation plot and scratched analysis of GLP-1 radio ligand binding to the cloned
human[7]GLP1 receptor in the absence or presence of compound 2.
In the saturation plot the presence of compound 2 in GLP-1 is increased then GLP -1 alone is given in fig 2
Fig. 2
VII. CONCLUSION
The mathematical model also reflects the same effects of GLP-1 receptor in the absence or presence of
compound 2 in fig 2 which are beautifully fitted with fourier transform of the Greens function of PDE is
obtained in fig (1). The results matching with the mathwematical and medical report.
REFERENCES
[1] M.F.Bru, “Wishart Processes”, Journel of Theoretical Probability, Vol. 4, No.4,1991,pp.725-751
[2] M.Escobar, B.Gotz,L.Seco and R.Zagst, “Pricing of a CDO on Stochastically correlated Underlyings,”
Quantitative Finance, Vol.10, No.3,2007, pp.265-277
[3] C.Gourieroux,J.Jasiak and R.Sufana, “Derivative Pricing with Multivariate Stochastic
Volatility:Application to credit Risk,” Working Paper,2004.
[4] C.Gourieroux and R.Sufana, “The Wishart Autoregressive Process of Multivariate Stochastic
Volatility,” Econometrics, Vol.150, No.2, 2009, pp. 167-181.
Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39
www.ijera.com 39 | P a g e
[5] J.Dafonseca, M.Grasselli and F.Ielpo, “Estimating the Wishart Affine Stochastic Correlation Model
Using the Empirical characteristic Function” Working paper ESIL V,RR-35,2007.
[6] J.Dafonseca, M.Grasselli and C.Tebaldi, “A Multifactor Volatility Heston Model”, Quantitative
Finance,Vol.8 No.6, 2006, pp. 591-604.
[7] Lotte Bjerre Knudsen, Dan Kiel et al., “Small molecule agonists for the glucagon like peptide 1
receptor”, PNAs, Vol.104, No.3, 2007, pp.937-942.
[8] Lakshmi S and Senthilkumar P 2007, “Stochastic model for cortisol secretion due to human stress ”
Indian Academy of Mathematics vol 29, (No.2):313-321
[9] Lakshmi S and Durga Devi (2014) “A multi variate model for combined propranotol / TSST paradigm”
Aryabhatta. J of Math & Info. Vol. 6(1) pp 103-108.
[10] A.Sepp, “Extended Creditgrades Model with Stochastic Volatility and Jumps,” Wilmott
Magazine,2006, pp.50-62.

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A Stochastic Model by the Fourier Transform of Pde for the Glp - 1

  • 1. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 34 | P a g e A Stochastic Model by the Fourier Transform of Pde for the Glp - 1 Dr. P. Senthilkumar** and D. Sargunasundari* ** Assistant Professor, Department of Mathematics, Rajah Serfoji Government College, Thanjavur, India. * Assistant Professor, Department of Mathematics, Bharath College of Science & Management, Thanjavur, India. Abstract The peptide hormone glucagon like peptide GLP -1 has most important actions resulting in glucose lowering along with weight loss in patients with type 2 diabetes. As a peptide hormone, GLP -1 has to be administered by injection. A few small-molecule agonists to peptide hormone receptors have been described. Here we develop a model for credit risk based on a model with stochastic eigen values called principal component stochastic covariance. The fourier transform of the Green function of the pricing PDE is,          ekk e kB )1()1( 1 .),( Keywords: GLP- 1, stochastic models, wishart process, stochastic covariance. 2000 Mathematics subject Classification: 60 H15 I. INTRODUCTION GLP-1 is one of the incretine, is a natural postprandial hormone released in response to nutrient intake and acts to stimulate insulin secretion. GLP -1 has attracted much interest as a future treatment for type -2 diabetes because it has multiple antidiabetic actions and at the same time, lowers body weight. The compounds were not antagonized by the selective GLP-1 receptor antagonist, exendin. Exendin is a fragment of a close analog of GLP-1 and must be expected to bind at the orthosteric agonist binding site. The mechanism behind the phenomenon was investigated further in a saturation binding experiment measuring the affinity and number of binding sites for GLP-1 in the absence or presence of compound 2. II. NOTATIONS Di  Symmetric positive definite matrix Wi  Brownian motion r(t)  Risk free interest rate di(t)  Dividend yield for the ith firm Tr  Trace of a matrix i  Stopping time )(|| ti   Truncating factor III. THE CREDIT GRADES WISHART PROCESS: In Credit Grades model, we assumes that volatility is deterministic. By means of stochastic covariance wishart process, we extend credit grades model. A wishart process with integer degree of freedom k is a sum of k independent n-dimensional Ornstein –uhlenbeck process. Consider  k k k V 1 as an independent set of Ornstein – Uhlenbeck process. )()()( k t k t k t RdWdtBVdV  Where B and R are (n,n ) matrices with R invertible[1,2]. Then a wishart process of degree k is defined as RESEARCH ARTICLE OPEN ACCESS
  • 2. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 35 | P a g e   k k k t k tt VVY 1 )'()( , Where )(k tV is the transpose of the Vector )(k tV . Here By using a Ito’s lemma, to find a diffusion SDE for the process tY    )( 1 )'()()'()()'()( .. kK k k t k t k t k t k t k tt dVdVdVVVdVdY =    k k k t k t k t k ttt RdWVVRdWdtBYBYRKR 1 ')'()()'()('' )( Here the term of the SDE contains tY , but the diffusion part contains the terms )(k tV and )'(k tV . Also tY satisfies the following matrix SDE.,[3]   '2 1 2 1'' RdWYYRdWdtBYBYRKRdY ttttttt  , …….(1) Where tW is an n x n standard Brownian motion matrix. IV. THE DYNAMICS OF THE ASSETS : The assets are defined on a probability space ),,( RF Where   0ttF is the information up to time t and R is the risk – natural measure equivalent to the measure P. Let us assume that the ith firm’s asset price per share is given by Ai(t). Here we review the results regarding the dynamics of the assets with stochastic covariance wishart process. Assume the asset’s prices follow the multivariate real – world model,   A tttiit dWYdtYDTrAd 2 1 ))((ln   '2 1 2 1' qdwYYMYMYdY tttttt   '2 1' )'( RdwYRdWdtMYMYdY ttttt    ……(2) Here the vector  n ...............1 is constant and Di is a symmetric positive definite matrix, the log price process has the drift term,      dtYDTAdE tiitt ln   and the Quadratic variation dtYAdV ttt )ln( Also we assume that the Brownian motion driving the assets and the Brownian motions driving the wishart proves are uncorrelated.   0tiYDTr accounts for risk premium. For the transition distribution of At+h given At and  tY We have   ,,ln~)(,/ln             ht t u ht t uitttht duYduYDTrANYAA  and the unconditional probability function can be found by Integration over the distribution function of  ht t u duY Now that we have identified the dynamics of the assets, we explain the mechanism of the Credit Grades model, As before, we assume that the ith firm’s value At(t) is driven by the dynamics       ttttttt ttiii YRRdZYdtMYMYdY dWYIdttdtrtAdiagtdA " )''( ]))()())[(()( ……. (3) Where =RR for some >n-1 and M is a negative definite matrix.
  • 3. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 36 | P a g e V. EQUITY CALL OPTIONS The price of a European call option on the equity is calculated by discounting the risk – neutral expectation of the payoff at maturity. Since       TTiTnTi ii KSKS     |||| ,, the price of the call option could be rewritten as Vcall (t, Y, Si, k) =                      KSdssrE TTi T t Q SYt ii ||)(exp ,),,( =                     TTi T t Q SYt ii KSdssrE ||)()(exp ,),,( The price of a single name derivative on one of the equities satisfies the partial differential equation[4,5]. Ut + ),( iSYA – rU = 0 Here the price of an equity call option is given by the PDE is     0)()()( 2 1 2  rUUAVStdtrUtDSYU YsiiSSiiiit iii …… (4) U(t,0) = 0, U(T,S) = (S-k)+ , where A(Y,S) is the infinitesimal generator of the joint process (S, Y) . We first joint change the variable by         )( )( ln tD tDS x i ii i         )( )( ln tD ktD a i i i and G(t,xi) = exp (  T t dssr )( )( ),( TD StU i i to transform the PDE to         aixi i Yiiiiit eexTUtG GAGxxGxYG ,,0)0,( ,0 2 1 …..(5) The Fourier transform of the Green’s function of PDE is given by[6]   ,),,( ),((, dkeXYq YkBTkAiky j rj        …..(6) Where,     kkkB ,),(),( 21 1 22                0 ),('),( dukuBRRTrkA With          2221 1211                  ' 4 1 2 1 '2 exp 2 MIk RRM  Now that we have found the fourier transform of the Green’s function of the pricing PDE, we solve the pricing problem for an equity call option by the method of images.
  • 4. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 37 | P a g e VI. RESULT The price of a call option on Sj(t) with maturity date T and strike price k is given by, V(t,Sj)=   ),()(exp)( yZdssrKTD T t           y = ln(S+D(t)) - ln(D(t)+K)+   T t dssdsr ))()(( b = ln(D(t)) - ln(D(t)+K)+   T t dssdsr ))()(( and the function z is defined by      0 )),((),( 2 )))2cos(()(cos( ),( ds kbyykee eeyZ YkBTkAy by r    ….(7) If in the dynamics of the asset (3), We assume n=1 and for the parameters 2 k M  , 2  R and k' , we have ),( kB  = 22 12   Now to find 12 and 22 , we have[8,9,10],              22 ) 4 1 ( 2 1 2 2 2 k k E   E e  is a 2 x2 matrix with     2 2 4 222 12 2 )( ),(             eek k     2 222 22 2 )()(( ),(     ekek k  22  k Therefore ),( kB  = e =         ekk e )1()1( 1 …… (8)
  • 5. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 38 | P a g e Fig. 1 Example As per the data the saturation plot and scratched analysis of GLP-1 radio ligand binding to the cloned human[7]GLP1 receptor in the absence or presence of compound 2. In the saturation plot the presence of compound 2 in GLP-1 is increased then GLP -1 alone is given in fig 2 Fig. 2 VII. CONCLUSION The mathematical model also reflects the same effects of GLP-1 receptor in the absence or presence of compound 2 in fig 2 which are beautifully fitted with fourier transform of the Greens function of PDE is obtained in fig (1). The results matching with the mathwematical and medical report. REFERENCES [1] M.F.Bru, “Wishart Processes”, Journel of Theoretical Probability, Vol. 4, No.4,1991,pp.725-751 [2] M.Escobar, B.Gotz,L.Seco and R.Zagst, “Pricing of a CDO on Stochastically correlated Underlyings,” Quantitative Finance, Vol.10, No.3,2007, pp.265-277 [3] C.Gourieroux,J.Jasiak and R.Sufana, “Derivative Pricing with Multivariate Stochastic Volatility:Application to credit Risk,” Working Paper,2004. [4] C.Gourieroux and R.Sufana, “The Wishart Autoregressive Process of Multivariate Stochastic Volatility,” Econometrics, Vol.150, No.2, 2009, pp. 167-181.
  • 6. Dr. P. Senthilkumar Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 5, ( Part -1) May 2015, pp.34-39 www.ijera.com 39 | P a g e [5] J.Dafonseca, M.Grasselli and F.Ielpo, “Estimating the Wishart Affine Stochastic Correlation Model Using the Empirical characteristic Function” Working paper ESIL V,RR-35,2007. [6] J.Dafonseca, M.Grasselli and C.Tebaldi, “A Multifactor Volatility Heston Model”, Quantitative Finance,Vol.8 No.6, 2006, pp. 591-604. [7] Lotte Bjerre Knudsen, Dan Kiel et al., “Small molecule agonists for the glucagon like peptide 1 receptor”, PNAs, Vol.104, No.3, 2007, pp.937-942. [8] Lakshmi S and Senthilkumar P 2007, “Stochastic model for cortisol secretion due to human stress ” Indian Academy of Mathematics vol 29, (No.2):313-321 [9] Lakshmi S and Durga Devi (2014) “A multi variate model for combined propranotol / TSST paradigm” Aryabhatta. J of Math & Info. Vol. 6(1) pp 103-108. [10] A.Sepp, “Extended Creditgrades Model with Stochastic Volatility and Jumps,” Wilmott Magazine,2006, pp.50-62.