Racecadotril is an effective and safe treatment for acute diarrhoea in children and adults. Racecadotril is an enkephalinase inhibitor that decreases intestinal hypersecretion but does not effect motility in humans and animals. Racecadotril through inhibition of enkephalinase, reinforces the physiological activity of endogenous enkephalins and therefor shows antisecretory activity. Racecadotril reduces the severity of diarrhoea, the duration of diarrhoea and the durtion of hospitalization.The dose of Racecadotril is 1.5mg/kg 8 hourly and is well tolerated in all age groups.
