7. how can differences between individuals such us as SNPs lead to.pdf

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7. how can differences between individuals such us as SNP\'s lead to persistent expression of lactase is some people but not in others? Solution Lactase persistence is the continued activity of the enzyme lactase in adulthood, only function of this enzyme is the digestion of lactose in milk, in most mammal species, the activity of the enzyme is dramatically reduced after weaning. Two mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase expression. C-14010, G-13907, and G-13915, T13910 and A22018 are related to lactase persistence.Schultheis et.al. suggests this trait is strongly associated with a C to T substitution at a polymorphic site 13,910 bp upstream of the lactase gene. As per Swallow DM\'s paper stated that , \"A putative causal nucleotide change has been identified and occurs on the background of a very extended haplotype that is frequent in Northern Europeans, where lactase persistence is frequent. This single nucleotide polymorphism is located 14 kb upstream from the start of transcription of lactase in an intron of the adjacent gene MCM6.\" So if the single nucleotide polymorphism occurs then the lactase persistance is seen in some individuals else not..

7. how can differences between individuals such us as SNP's lead to persistent expression of
lactase is some people but not in others?
Solution
Lactase persistence is the continued activity of the enzyme lactase in adulthood, only function of
this enzyme is the digestion of lactose in milk, in most mammal species, the activity of the
enzyme is dramatically reduced after weaning.
Two mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase
expression.
C-14010, G-13907, and G-13915, T13910 and A22018 are related to lactase
persistence.Schultheis et.al. suggests this trait is strongly associated with a C to T substitution at
a polymorphic site 13,910 bp upstream of the lactase gene.
As per Swallow DM's paper stated that , "A putative causal nucleotide change has been
identified and occurs on the background of a very extended haplotype that is frequent in
Northern Europeans, where lactase persistence is frequent. This single nucleotide polymorphism
is located 14 kb upstream from the start of transcription of lactase in an intron of the adjacent
gene MCM6."
So if the single nucleotide polymorphism occurs then the lactase persistance is seen in some
individuals else not.

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Question 11 of 24 In E. coli, three structural Deand enzymes A. D, an.pdf

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fathimafancyjeweller

Question 1 5 pts Given the cash flow diagram below, evaluate the value of \"A\" if the \"F\" value is $24.000 for an interest rate of 7%. ?? 4A Solution Future Value of investents: Year Investment Future Value of Investment of 1 Future Value of Investment a b c=1.07^(5-a) d=b*c 1 A 1.3108 1.3108 A 2 2A 1.2250 2.4501 A 3 3A 1.1449 3.4347 A 4 4A 1.0700 4.2800 A 11.4756 A Now, As per question, 11.4756 A = $ 24,000 or, A = $ 2,091.40 Thus, Value of A $ 2,091.40.

Question 1. Dscribe the change you observed when you added 1 mL of 0.pdf

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fathimafancyjeweller

Project #8 requires you to find an escape path from a given starting point in a maze. The maze (or swamp or mine field etc.) is a square 2D array of int. A value of zero in any cell represents a wall (land mine or quicksand etc.) while a value of one represents a possible step to take. Each input file will have a line at the top of the file that has the square dimension of the matrix followed by the drop in point. The drop in point is the row/col pair indicating where you are dropped into the swamp. You escape the swamp by taking one step at a time to any adjacent square that is a 1. You are not allowed to step on a zero cell. You must somehow remember which squares you have already stepped on in a path so that you don\'t get into an infinite loop. The five input files you are given have cycles and dead ends and valid paths to the edge of the swamp. The starter file that you are given has two methods already written for you. The first given method loads the grid values and generates the 2D int array to hold the 1s and 0s. The second method echo\'s out the swamp to the screen before calling the method that you must fill in - which will print all the escape paths. Do not modify main any more than needed. Do not modify the given methods that load or print the grid. You are just to write and call the method(s) that print all escape paths. the only output you are to write is one line per escape path and it must be in the exact format as my sample output. If there are no escape paths then your code prints out no additional output. Your escape path lines may be in a different order than mine but the row,col values must match exactly in matching lines. Your program must find and print ALL the escape paths. Lines may be in any order though. Do not print any other output of any kind other than what my solution demo does. DO NOT PRINT \"DEAD END\" OR *ANY* OUTPUT IF THERE ARE NO PATHS OUT. JUST PRINT NOTHING! input file: output should look like: Solution input0.txt 10 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 0 1 0 1 0 0 0 0 0 1 0 1 1 0 0 0 0 0 1 0 1 0 0 1 0 0 0 1 0 0 1 1 1 1 0 0 0 0 1 0 1 0 1 0 1 0 0 0 0 1 0 1 0 1 0 0 0 0 1 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 Project2.java import java.io.*; import java.util.*; public class Project2 { public static void main(String[] args) throws Exception { int[] dropInPt = new int[2]; // row and col will be on the 2nd line of input file; int[][] swamp = loadSwamp( args[0], dropInPt ); int row=dropInPt[0], col = dropInPt[1]; printSwamp( \"\ SWAMP: dropped in at: [\"+row+\",\"+col+\"]\ \",swamp ); System.out.println(\"\ ESCAPE PATHS:\ \"); // YOUR CODE HERE. DECLARE WHATEVER OBJECTS AND VARIABLES NEEDED // CALL YOUR METHOD(s) TO PRINT ALL ESCAPE PATHS printPath(swamp, dropInPt); } // END MAIN // ################################################### // DO NOT MODIFY THIS METHOD // ---------------------------------------------------------------- private static void printSwamp(String label, int[][] swamp ) { System.o.

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fathimafancyjeweller

Choose one field such as academia, health, consulting, business, management, and so on and discuss the importance of followership in that field. Solution A follower can be a personality kind, as a foothold in a very hierarchy, as a role, or as a collection of traits and behaviors. Studies of followership have created numerous theories together with an attribute, activity attributes, role, and constructionist theories additionally to exploring myths or misunderstandings concerning followership. ---Effective followership coaching within the school room is difficult due to media messages that preference leadership, internal schemas command by students that ignore followership, and cultural biases against it. undergrad and graduate students are proof against the thought of followership and followership have been taken as leadership poorly enacted or as subsiding for a lesser position. In recent years, attitudes have begun to change the students have noted that following is an expected, healthy a part of a reciprocal relationship in social media which it failed to carry negative connotations. Although a student’s contribution within the schoolroom has such high significance, the school admissions system has nevertheless to seek out the way to acknowledge and reward students who have ceaselessly created these contributions. on condition that outstanding schoolroom contributions are neglected, nevertheless play such an important role, it\'s the responsibility of the school admissions system to seek out the way to spot them. ---In hospitals and tourism, being a good follower is vital for achieving the service-oriented goals of the many operations.In hospital operations, it\'s typically necessary for followers to figure severally of their leaders to holdout necessary tasks. it\'s been steered that incorporating followership into coaching and education in intentional, purposeful ways in which may assist operations in hospital and tourism. ---Followership, as outlined by Hurwitz (2008), is “accepting or enabling [italics original] the goal accomplishment of one’s leader”. within the context of franchising, the franchise may well be seen as an admirer as a result of he or she accepts the franchisor’s business plan and allows the franchisor’s goal accomplishment through the individual franchise operations. Leaders will begin by building structure price for followers and followership price could be a method of incorporating the construct of followership into the organization’s culture, policies, and practices as a result of leaders have followers it\'s their responsibility to line a vision, build trust, and encourage the followers with passion and hope. ---The Followership Learning Community (FLC) could be a learning community inside the International Leadership Organization (ILA) and is “dedicated to the event of information, competencies, and programs regarding the leader-follower relationship. it\'s the primary such educational or applies community dedi.

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Choose one field such as academia, health, consulting, business, man.pdf

fathimafancyjeweller

An intercalating agent: 1. Inserts between base pairs of the two strands of DNA 2. Makes double- stranded lesions in the DNA 3. Inserts between adjacent base pairs on a single strand of DNA 4. Commonly causes transversion mutations 5. Makes single-stranded lesions in the DNA Solution Chelating agent involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central atom. Usually these ligands are organic compounds, and are called chelants, chelators, chelating agents, or sequestering agents..

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fathimafancyjeweller

a trait is considered: discrete when: 1-The traits are intermediate between the recessive and dominant cases 2- the traits are obviously either there or not there [what I guess the answer is] 3- the traits are variable in the population 4- the traits are a result of multiple genes. when the allele of a trait is incompletely dominant: 1- the dominant trait masks the recessive trait 2- the recessive trait masks the dominant trait 3- the heterozygous individial is the same as the dominant. 4- the heterozygous individual is intermediate between the recessive and the dominant 5- the heterozygous individual expresses both traits. Solution A trait is considered discrete when the traits are either there or not there, eg Albinism, cystic fibrosis, Huntingtons disease, -option 2. Incomplete dominance is a form of intermediate inheritance where one allele for a specific trait is not completely expressed over its paired allele. This results in a third phenotype in which the expressed physical trait is a combination of the phenotypes of both the alleles. Option 4-the heterozygous individual is intermediate between the recessive and the dominant.

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