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DENTAL MANAGEMENT
OF
BLOOD DYSCRASIAS
Dental management
based on 2 concepts:
1. What you should know ?
2.What you should do?
BLOOD DYSCRASIAS
•
DISORDERS OF RED BLOOD CELLS
ANAEMIA

UP TO PUBERTY 11.0 G/DL
FEMALES, BELOW 11.5 G/DL
MALES BELOW 13.5 G/DL THE CRITERIA OF ANAEMIA.
TYPES OF ANEMIA
IRON DEFICIENCY ANEMIA
FOLATE DEFICIENCY ANEMIA AND PERNICIOUS ANEMIA
TYPES OF ANEMIA
SICKLE CELL ANEMIA
THE THALASSEMIAS
TYPES OF ANEMIA
APLASTIC ANEMIA
CLINICAL PRESENTATION
SIGNS AND SYMPTOMS
ORAL COMPLICATIONS AND MANIFESTATIONS
Patients with nutritional
causes of anemia (e.g.,
vitaminB12 or iron
deficiency) may show loss
of papillae from the
tongue and atrophic
changes in the oral
mucosa.
Angular cheilitis and
aphthae may be found.
Patients also may report
burning or sore tongue.
ORAL COMPLICATIONS AND MANIFESTATIONS

PLUMMER-VINSON SYNDROME
ORAL COMPLICATIONS AND MANIFESTATIONS
 HEMOLYTIC ANEMIA
“HAIR ON END”
DELAYED ERUPTION OF TEETH
HAIR ON END APPEARANCE
SCREENING LABORATORY TESTS
Type Etiology Tests to Discriminate Types of Anemia
Microcytic
anemia
Iron deficiency Serum iron, ferritin, total iron-binding capacity (TIBC),
transferrin saturation, bone marrow aspirate; also, stool
examination for occult blood
Macrocytic
anemia
Folate deficiency CBC, serum folate level
Macrocytic
anemia
Pernicious anemia CBC, serum vitamin B12
Normocytic
anemia
G-6-PD reticulocyte count, indirect bilirubin levels
Normocytic
anemia
Sickle cell anemia Sickledex, high-performance liquid chromatography,
hemoglobin electrophoresis, reticulocyte count, indirect
bilirubin levels
Normocytic
anemia
Aplastic anemia Erythropoietin levels, bone marrow aspirate
DENTAL MANAGEMENT

REFERRED


IT IS IMPORTANT FOR THE DENTIST TO ATTEMPT TO
IDENTIFY THESE PATIENTS THROUGH HISTORY AND CLINICAL
EXAMINATION BEFORE STARTING ANY TREATMENT
DENTAL MANAGEMENT


DENTAL MANAGEMENT

11 G/DL

11 G/DL
91%
DENTAL MANAGEMENT
 G-6-PD DEFICIENCY
THUS, DENTAL INFECTIONS SHOULD BE AVOIDED,
AND IF THEY OCCUR, THEY MUST BE DEALT WITH EFFECTIVELY
DENTAL MANAGEMENT

SICKLE CELL ANEMIA

DENTAL MANAGEMENT
 APLASTIC ANEMIA
DISORDERS OF WHITE BLOOD CELLS
LEUKOCYTOSIS AND LEUKOPENIA
 4400 TO
11,000/ΜL
 LEUKOCYTOSIS
PHYSIOLOGIC PATHOLOGIC
LEUKOCYTOSIS AND LEUKOPENIA

LEUKEMIA



LEUKEMIA


ORAL MANIFESTATIONS OF ACUTE LEUKEMIA
 GINGIVAL ENLARGEMENT

GINGIVAL BLEEDING
A LOCALIZED MASS OF LEUKEMIC CELLS
ORAL MANIFESTATIONS OF ACUTE LEUKEMIA
GINGIVAL ENLARGEMENT
ORAL MANIFESTATIONS OF ACUTE LEUKEMIA
LEUKEMIA CHLOROMA
ORAL MANIFESTATIONS OF CHRONIC LEUKEMIA
CHRONIC LYMPHOCYTIC LEUKEMIA
LYMPHADENOPATHY
HODGKIN LYMPHOMA
LYMPHOMA
HODGKIN LYMPHOMA

NON-HODGKIN LYMPHOMA


ORAL COMPLICATIONS AND MANIFESTATIONS


NON-HODGKIN LYMPHOMA LYMPHADENOPATHY
LYMPHOMA OF THE ORAL CAVITY
WALDEYER’S RING LYMPHOMA
BURKITT LYMPHOMA


ENDEMIC FORM BURKITT LYMPHOMA
Prof. Raja Kummoona Middle east jaw lymphoma
ORAL COMPLICATIONS AND MANIFESTATIONS

JAW LYMPHOMA
MULTIPLE MYELOMA

MULTIPLE MYELOMA

“PUNCHED-OUT”
MULTIPLE MYELOMA
PUNCHED-OUT LESIONS
MULTIPLE MYLOMA OF THE JAW
RECOGNITION OF DISORDERS OF WHITE BLOOD CELLS
AND MEDICAL CONSIDERATIONS

RECOGNITION OF DISORDERS OF WHITE BLOOD
CELLS AND MEDICAL CONSIDERATIONS


TREATMENT PLANNING MODIFICATIONS
TREATMENT PLANNING MODIFICATIONS

 ORAL HYGIENE INSTRUCTIONS
CARIES AND
INFECTION SHOULD BE ELIMINATED
TREATMENT SHOULD BE DIRECTED FIRST TOWARD ACUTE NEEDS
ORAL HEALTH CARE AND ORAL COMPLICATIONS
DURING MEDICAL THERAPY.

MUCOSITIS, NEUTROPENIA, INFECTION, EXCESSIVE
BLEEDING

ORAL HEALTH CARE AND ORAL COMPLICATIONS
DURING MEDICAL THERAPY.



ORAL HEALTH CARE AND ORAL COMPLICATIONS
DURING MEDICAL THERAPY.
SUBMUCOSAL HEMORRHAGE


Dental management Blood dyscrasia

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Dental management Blood dyscrasia