The Physiology of Blood Cells and Functions

THE PHYSIOLOGY OF BLOOD Introduction Lect 1 [email_address]

WHAT IS BLOOD ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

[email_address] HEMATOLOGY: THE STUDY OF BLOOD MADE POSSIBLE BY MICROSCOPY

THE COMPOSITION OF BLOOD PLASMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address] BLOOD PLASMA WATER SOLUTES PROTEINS ELECTRO -LYTES ORGANIC MOLECULES

THE FORMED ELEMENT: CELLS [email_address] BLOOD CELLS ERYTHROCYTES LEUCOCYTES THROMBOCYTES

BLOOD: COMPOSITION [email_address]

FUNCTIONS OF BLOOD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

[email_address] BLOOD:TRANSPORTING HORMONE MOLECULES

OXYGEN & CO 2 TRANSPORT [email_address]

[object Object],[object Object],[object Object],[object Object],[object Object],[email_address] FUNCTIONS OF BLOOD

WHAT IS BLOOD VOLUME? ,[object Object],[object Object],[email_address]

EXPRESSION OF BLOOD VOLUME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

METHODS OF MEASURING BLOOD VOLUME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

DYE DILUTION TECHNIQUE [email_address] V 1 = VOLUME C 1 = CONCENTRATION OF DYE V 2 = VOLUME C 2 = CONC. OF DYE V 1 X C 1 = V 2 X C 2 OR V 2 = V 1 X C 1 = Amount of Dye injected C 2 Conc. Of the dye in the Plasma

HEMATOCRIT (PCV) ,[object Object],[object Object],[object Object],[email_address]

HEMATOCRIT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

BLOOD VOLUME: PHYSIOLOGICAL VARIATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

BLOOD VOLUME & AGE [email_address] AGE BLOOD VOLUME in Liters AT BIRTH 0.3 6 Months 0.5 1 year 0.7 2yrs 6 months 1.0 4 years 1.3 7 years 1.7 10 years 2.5(Girls); 3.2 (Boys) ADULTS 5 (Men) 4.5 (Women)

BLOOD VOLUME: PHYSIOLOGICAL VARIATIONS ,[object Object],[object Object],[object Object],[object Object],[email_address]

BLOOD VOLUME: PHYSIOLOGICAL VARIATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

BLOOD VOLUME: PATHOLOGICAL VARIATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

HYPOVOLEMIA: CAUSES (contd) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

HYPOVOLEMIA: CAUSES (contd) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

TREATMENT FOR BLOOD LOSS ,[object Object],[object Object],[object Object],[email_address]

HEMOPOIESIS & ERYTHROPOIESIS [email_address]

HEMOPOIESIS: INTRO ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address] STEM CELL THEORY

PROGENITOR CELLS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

BLOOD CELLS: DEVELOPMENT [email_address] PROGENITOR CELLS LYMPHOID CELLS PRO NORMOBLAST MEGA KARYOBLAST MYELOBLAST MONOBLAST LYMPHOCYTES ERYTHROCYTES THROMBOCYTES GRANULOCYTES MONOCYTES

ERYTHROPOIESIS: SITES/PHASES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

ERYTHROPOIESIS: SITES/PHASES contd. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

ERYTHROPOIESIS [email_address] PROERYTHROBLAST BASOPHILIC ERYTHROBLAST POLY CHROMATOPHILIC ERYTHRO BLAST ORTHOCHROMATIC ERYTHROBLAST RETICULOCYTE MATURE ERYTHROCYTES

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address] FACTORS REGULATING ERYTHROPOIESIS

[object Object],[object Object],[object Object],[object Object],[object Object],[email_address] ERYTHROPOIETIN

VITAMINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[email_address]

IRON ,[object Object],[object Object],[object Object],[email_address]

The Physiology of Blood Cells and Functions

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The Physiology of Blood Cells and Functions