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C H O I C E  O F  H E A R T  V A L V E S  Criteria for patient selection Presented by Public  Awareness  Program
Four Predictors of Performance of a valve ,[object Object],[object Object],[object Object],[object Object]
1960’s - Commercially Available Mechanical Heart Valves ,[object Object],[object Object],[object Object]
1960’s ,[object Object],[object Object],[object Object],[object Object],[object Object]
1960’s ,[object Object],[object Object],[object Object]
1960’s ,[object Object],[object Object],[object Object],[object Object],[object Object]
Early Product Failures
1977 ,[object Object],[object Object],[object Object],[object Object]
Tissue Valve History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tissue Valve History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What kinds of heart valves are available? Bioprosthetic Valves Mechanical  Valves How do you choose between these valves?
Two Main Sources of Bioprosthesis  Bov ine Pericardium ,[object Object],[object Object],[object Object],[object Object],Porcine
What kinds of heart valves are available? Bioprosthetic Valves ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Valves from human or animal tissue and sterilized for use How do you choose between these valves?
What kinds of heart valves are available? Mechanical Valves ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Valves made from Metal materials How do you choose between these valves?
Current Trends in Valve Implants Tissue valves have become more accepted in the U.S. due to concerns about quality of life and improved durability.  Mechanical valves, however, still compose a large part of valve implants, particularly in younger patients. U.S. Implant Trends Mechanical vs Tissue Valve Implants Mechanical 45% Tissue 55%
Indian Scenario
Valvular Heart Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
St. Jude Medical Tissue valve usage
Myths about Mechanical Valves ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mechanical   Prosthesis Cost Analysis : Anticoagulantion therapy INR Test  every 15-30 days No. of visits to Physicians Thrombolysis Treatment  of  Hemorrhage/Struck Valve Repeated Hospitalization
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Total:  Rs 1,300 to Rs 1,500 per month Mechanical   Prosthesis
Choice of Valve The  Patient Age Gender Compliance Concomitant Illness Lifestyle Cost Medical services
Choice of Valve Indian Scenario : Rheumatic Heart Disease Children  &  Young   Males  &  Females   Rural  &  Remote   Illiteracy &  Poverty   Ignorance
Choice of Valve in Children Mechanical  Prosthesis  Advantages
BIOPROSTHESIS  Advantages  in  Young  ,[object Object],[object Object],[object Object],[object Object]
BIOPROSTHESIS  Advantages in Females  ,[object Object],[object Object],[object Object],[object Object]
BIOPROSTHESIS Advantages in Middle Age ,[object Object],[object Object],[object Object]
BIOPROSTHESIS Advantages in the Elderly  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Life with a Bioprosthetic Valve ,[object Object],[object Object],[object Object],[object Object],[object Object]
If I Need A Valve Surgery VALVE REPAIR Follow Up Leave it to the   Cardiologist
If Valve Needs to be Replaced TISSUE VALVE ( Young female, old life exp<20 yrs) No major Follow Up Re do after 10-15 yrs
If tissue valve cannot be used MECHANICAL VALVE ( young patient, poor, not ready for re op) Regular Follow Up Required Compromised lifestyle Lifetime anticoagulation required
Decisions to make Is Lifestyle Important?
Thank You!

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Choices in Valve Replacement - Desun Hospital Health Insights

  • 1. C H O I C E O F H E A R T V A L V E S Criteria for patient selection Presented by Public Awareness Program
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  • 11. What kinds of heart valves are available? Bioprosthetic Valves Mechanical Valves How do you choose between these valves?
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  • 15. Current Trends in Valve Implants Tissue valves have become more accepted in the U.S. due to concerns about quality of life and improved durability. Mechanical valves, however, still compose a large part of valve implants, particularly in younger patients. U.S. Implant Trends Mechanical vs Tissue Valve Implants Mechanical 45% Tissue 55%
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  • 18. St. Jude Medical Tissue valve usage
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  • 20. Mechanical Prosthesis Cost Analysis : Anticoagulantion therapy INR Test every 15-30 days No. of visits to Physicians Thrombolysis Treatment of Hemorrhage/Struck Valve Repeated Hospitalization
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  • 22. Choice of Valve The Patient Age Gender Compliance Concomitant Illness Lifestyle Cost Medical services
  • 23. Choice of Valve Indian Scenario : Rheumatic Heart Disease Children & Young Males & Females Rural & Remote Illiteracy & Poverty Ignorance
  • 24. Choice of Valve in Children Mechanical Prosthesis Advantages
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  • 30. If I Need A Valve Surgery VALVE REPAIR Follow Up Leave it to the Cardiologist
  • 31. If Valve Needs to be Replaced TISSUE VALVE ( Young female, old life exp<20 yrs) No major Follow Up Re do after 10-15 yrs
  • 32. If tissue valve cannot be used MECHANICAL VALVE ( young patient, poor, not ready for re op) Regular Follow Up Required Compromised lifestyle Lifetime anticoagulation required
  • 33. Decisions to make Is Lifestyle Important?

Editor's Notes

  1. Dwight Harken began the modern era of prosthetic valve replacement by insertion of his double cage-ball valve into the aortic orifice below the coronary ostia following excision of the diseased cusps. Some of his patients were still alive after 20 years. Albert Starr, a physician, and Lowell Edwards, an electrical engineer, simplified the caged-ball valve by using a single titanium cage, a silastic ball, and a sewing ring covered with teflon. The Starr-Edwards valve was first implanted in the mitral position in 1960, and leter in the aortic position. It became commercially available in 1965. The sewing ring made it easy to suture silastic ball had a tendency to absorb liquid and become deformed, sometimes jamming central flow obstruction cause high pressure gradients, especially in patients with a narrow aortic root
  2. Jerome Kay, a surgeon, and Donald Shiley, and engineer, introduced a low-profile disc valve for use in the mitral position. Some surgeons used it in the aortic position too, because, unlike the caged-ball valve, the disc did not extend into the supravalvular ridge; high valvular gradients were still present; valve was subject to wear and thrombosis Other sliding disc configurations were also developed
  3. Juro Wado (Japan) developed a tilting disc valve with teflon hinges and an opening angle of 80 degrees; the tilting disc brought down pressure gradients; the teflon hinges wore out Shiley and Dr. Viking Bjork developed a hingeless low-profile tilting disc valve made of Delrin, and designed with an opening angle of 60 degrees. The Bjork-Shiley disk was used successfully in the aortic and mitral position.
  4. Examples of failed valves: - crack in the silastic rubber ball - thrombus on the valve housing - wear on the post’s fabric covering - strut failure of a Bjork-Shiley valve (valve model was recalled, then redesigned as a monostrut to avoid this problem) NOTE: patient with this valve survived the failure