This document provides a comprehensive overview of regional anesthesia and its historical development, detailing local anesthetic methods for pain management during surgical procedures while maintaining patient consciousness. It discusses the anatomy, physiology, classification of anesthesia techniques, advantages, and disadvantages, as well as complications and contraindications related to peripheral nerve blocks. Additionally, it emphasizes the importance of modern equipment, such as ultrasound and nerve stimulators, in improving the efficacy and safety of these procedures.