Ovidac Injection (Generic Human Chorionic Gonadotropin Injection) is used in females to help conception occur. It is usually given in combination with other medicines such as menotropins and urofollitropin. Many women being treated with these medicines usually have already tried clomiphene alone (e.g., Serophene) and have not been able to conceive yet. Human Chorionic Gonadotropin is also used in in vitro fertilization (IVF) programs. Chorionic gonadotropin is a medicine whose medical effects are almost the same as those of Luteinizing Hormone (LH), which is produced by the pituitary gland. In males, LH and Human Chorionic Gonadotropin (Ovidac injection) stimulate the testes to produce male hormones such as Testosterone. Testosterone causes the enlargement of the penis and testes and the growth of pubic and underarm hair. It also increases the production of sperm. Although Human Chorionic Gonadotropin has been prescribed to help some patients lose weight, it should never be used this way. When used improperly, Human Chorionic Gonadotropin (Ovidac) can cause serious problems.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Ovidac Injection (Generic Human Chorionic Gonadotropin
Injection) is used in females to help conception occur. It is
usually given in combination with other medicines such as
menotropins and urofollitropin. Many women being treated
with these medicines usually have already tried clomiphene
alone (e.g., Serophene) and have not been able to conceive yet.
Human Chorionic Gonadotropin is also used in in vitro
fertilization (IVF) programs. Chorionic gonadotropin is a
medicine whose medical effects are almost the same as those
of Luteinizing Hormone (LH), which is produced by the
pituitary gland.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
In males, LH and Human Chorionic Gonadotropin (Ovidac
injection) stimulate the testes to produce male hormones
such as Testosterone. Testosterone causes the enlargement of
the penis and testes and the growth of pubic and underarm
hair. It also increases the production of sperm.
Although Human Chorionic Gonadotropin has been prescribed
to help some patients lose weight, it should never be used this
way. When used improperly, Human Chorionic Gonadotropin
(Ovidac) can cause serious problems.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Active Ingredient
The active ingredient present in Ovidac injection is
Human Chorionic Gonadotropin. Each vial of Ovidac injection
contains 2000 iu, 5000 iu or 10000 iu of purified Human
Chorionic Gonadotropin.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Ovidac Injections are manufactured by Bayer Zydus Pharma,
India in the strengths of 2000 iu, 5000 iu or 10000 iu of
purified Human Chorionic Gonadotropin.
(Website: https://www.bayerzyduspharma.com/en/ )
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Human Chorionic Gonadotropin Injections – Brand Names
Human Chorionic Gonadotropin Injections
are available under various drug trade
names that include Pregynl, Ovidac,
Ovidrel, Novarel, Vitagon, Chorex, Corion
and Choragon.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Uses of Ovidac Injections
Prepubertal cryptorchidism not due to anatomical obstruction. In general, Human
Chorionic Gonadotropin is thought to induce testicular descent in situations when
descent would have occurred at puberty. HCG thus may help predict whether or
not orchiopexy will be needed in the future. Although, in some cases, descent
following HCG administration is permanent, in most cases, the response is
temporary. Therapy is usually instituted between the ages four and nine.
Selected cases of hypogonadotropic hypogonadism (hypogonadism secondary to a
pituitary deficiency) in males.
Ovidac Injection (Generic Human Chorionic Gonadotropin Injection) is also used
for induction of ovulation and pregnancy in the anovulatory, infertile woman in
whom the cause of anovulation is secondary and not due to primary ovarian
failure, and who has been appropriately pretreated with human menotropins.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Ovidac Injection Dosage
The dosage of Ovidac Injection (Generic Human Chorionic Gonadotropin
Injection) is given below:
In the Female: Sterility due to the absence of follicle-ripening or ovulation.
5,000 IU to 10,000 IU hCG to induce ovulation, following treatment with an FSH (Follicle
Stimulating Hormone) or HMG (Human Menopausal Gonadotrophins) preparation.
In combination with FSH (Follicle Stimulating Hormone) or HMG (Human Menopausal
Gonadotrophin), promotion of controlled superovulation in medically assisted reproduction
programmes.
5,000 IU to 10,000 IU hCG 30 to 40 hours after the last FSH or HMG injection. Ovidac
injection should not be administered if the following criteria have not been met: at least 3
follicles greater than 17 mm in diameter are present with 17ß estradiol levels of at least
3500 pmol/L (920 picogram/ml). Oocyte collection is carried out 32 hours to 36 hours after
the hCG injection has been administered.As luteal phase support, two to three injections of
1,000 to 3,000 IU hCG each may be given within nine days of ovulation or embryo transfer,
for example on day 3, 6 and 9 after ovulation induction or embryo transfer.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Ovidac Injection Dosage
The dosage of Ovidac Injection (Generic Human Chorionic Gonadotropin
Injection) is given below:
In The Male:
Hypogonadotrophic Hypogonadism
5,000 IU to 10,000 IU hCG 2-3 times weekly.
Delayed puberty associated with insufficient gonadotrophic pituitary function.
1,500 IU hCG twice weekly for at least 6 months.
Sterility in selected cases of deficient spermatogenesis.
Usually, 3,000 IU hCG per week in combination with an FSH or HMG preparation. This
treatment must be continued for at least three months before any improvement in
spermatogenesis can be expected. During this treatment testosterone replacement therapy
must be suspended. Once achieved, the improvement can sometimes be maintained by hCG
alone.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Contraindications
Ovidac Injections are contraindicated in persons with a
hypersensitivity (allergy) to Human Chorionic Gonadotropin or
any of the other ingredients of this medicine.
The other contraindications include Presence of uncontrolled non-
gonadal endocrinopathies (e.g. thyroid, adrenal or pituitary
disorders), Breast, uterine, ovarian tumours, Vaginal bleeding of
unknown cause, Known or suspected androgen-dependent tumours
such as testicular tumours, carcinoma of the prostate or mammary
carcinoma in males, Malformations of the sexual organs
incompatible with pregnancy and Fibroid tumours of the uterus
incompatible with pregnancy.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Storage Instructions
Ovidac Injection (Generic Human Chorionic
Gonadotropin Injection) have to be stored at
controlled room temperature i.e. from 20°C to
25°C (68°F to 77°F) with excursions permitted
between 15° to 30°C (59° to 86°F).
Keep this as well as all other medicines away
from children and pets.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Warnings
Ovidac injection should be used in conjunction with human menopausal
gonadotropins only by physicians experienced with infertility problems
who are familiar with the criteria for patient selection, contraindications,
warnings, precautions, and adverse reactions.
The principal serious adverse reactions are: (1) Ovarian hyperstimulation,
a syndrome of sudden ovarian enlargement, ascites with or without pain
and/or pleural effusion, (2) Rupture of ovarian cysts with resultant
hemoperitoneum, (3) Multiple births and (4) Arterial thromboembolism.
Anaphylaxis and other hypersensitivity reactions have been reported with
urinary-derived hCG products.
Since androgens may cause fluid retention, Human Chorionic
Gonadotropin should be used with caution in patients with cardiac or
renal disease, epilepsy, migraine, or asthma.

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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Side Effects
Ovidac (Human Chorionic Gonadotropin Injection) Side
effects include Headache, irritability, restlessness,
depression, fatigue, edema, precocious puberty,
gynecomastia, pain at the site of injection.
Hypersensitivity reactions, both localized and systemic in
nature, have also been reported.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Overdose
The toxicity of Human Chorionic Gonadotrophic hormone is
very low. However, a very high dose of Ovidac may lead to
hyperstimulation of the ovaries.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
Ovidac Injections During Pregnancy
Human Chorionic Gonadotropin is classified by the US FDA as
Pregnancy Category X.
Defects of forelimbs and central nervous system and alterations in sex
ratio have been reported in mice receiving combined gonadotropin and
chorionic gonadotropin therapy in dosages to induce superovulation.
Alterations in sex ratio has been reported in animal studies on
combined gonadotropin and chorionic gonadotropin treatment in
dosages to induce superovulation.
There are no controlled data in human pregnancy. Human Chorionic
Gonadotropin (HCG) is considered contraindicated during pregnancy.
This medicine must not be administered after conception has occurred.
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Ovidac (Generic Human Chorionic Gonadotropin Injection)
For more details on
Ovidac Injections click here
Ovidac Injection (Generic Human Chorionic Gonadotropin Injection)
by Bayer Zydus Pharma, India.
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