Eutrig-HP Injections (Generic Human Chorionic Gonadotrophin Injections)

Eutrig-HP Injections (Generic Human Chorionic Gonadotrophin Injections)
© The Swiss Pharmacy

Eutrig-HP Injection (Generic Human Chorionic Gonadotrophin Injection)
is FDA approved for the treatment of hypogonadotropic hypogonadism,
prepubertal cryptorchidism, and ovulation induction.
HCG is a hormone that is used to cause ovulation and to treat infertility
in women. This medicine is not effective in women with primary ovarian
failure. In female infertility it can be used to cause women to ovulate
(Ovulation induction). Eutrig-HP is also used along with other fertility
medicines, to help produce eggs in medically assisted reproduction
programmes (IVF treatment).
Human Chorionic Gonadotropin Injections (HCG) is used in men to treat
hypogonadism, a condition in which the body doesn't produce enough
testosterone.
HCG is also used in young boys whose testicles have not descended
(dropped) into the scrotum as normally expected during growth. HCG is
usually given for this condition in boys who are 4 to 9 years old.

Eutrig-HP Injections (Generic Human Chorionic Gonadotrophin
Injections) are manufactured by Samarth Life Sciences Private
Limited, India in the strength of 2000iu, 5000iu and 10000iu.

Chemical Structure

The active pharmaceutical ingredient in Eutrig-HP injections is
Human Chorionic Gonadotropin. Each vial of Eutrig-HP injection
contains 2000iu, 5000iu or 10000iu of purified Human Chorionic
Gonadotropin.

Uses of Eutrig-HP 2000iu, 5000iu and 10000iu Injections:
Human Chorionic Gonadotropin (HCG), the active ingredient found in Eutrig-
HP Injection is a hormone that supports the normal development of an egg
in a woman's ovary, and stimulates the release of the egg during ovulation.
HCG (Eutrig-HP Injections) is used to cause ovulation and to treat infertility
in women, and to increase sperm count in men. HCG is also used in young
boys when their testicles have not dropped down into the scrotum normally.
This can be caused by a pituitary gland disorder.
Chorionic gonadotropin injection is a hormone used as a fertility medicine to
develop eggs in women who have not been able to become pregnant
because of problems in ovulation. It is also used to help men with low sperm
counts produce more sperms and used when testicles have not dropped
down in the scrotum which is caused by a pituitary gland problem.
URL: https://www.theswisspharmacy.com/product_info.php?info=p9973_Generic-Human-Chorionic-Gonadotrophin-Injection.html

Uses of Eutrig-HP 2000iu, 5000iu and 10000iu Injections:
In females, Chorionic Gonadotropin (Eutrig-HP Injection) is used to
help conception occur. It is usually given in combination with other
drugs such as menotropins and urofollitropin. Many women being
treated with these drugs usually have already tried clomiphene alone
and have not been able to conceive yet. Chorionic gonadotropin is
also used in in-vitro fertilization (IVF) programs.
In males, LH and chorionic gonadotropin stimulate the testes to
produce male hormones such as testosterone. Testosterone causes
the enlargement of the penis and testes and the growth of pubic and
underarm hair. It also increases the production of sperm.

Recommended Adult Dosage
The recommended dosage of Eutrig-HP Injections (Generic
Human Chorionic Gonadotrophin Injections) for various indications
is given below:
Usual Adult Dose for Ovulation Induction:
Ovulation Induction (if the cause of anovulation is secondary and not
due to primary ovarian failure):
Chorionic Gonadotropin: 5000 to 10,000 units IM one day following
last day of menotropins.
Recombinant chorionic gonadotropin: 250 mcg subcutaneously one
day following last dose of follicle-stimulating agent.

Recommended Adult Dosage
The recommended dosage of Eutrig-HP Injections (Generic
Human Chorionic Gonadotrophin Injections) for various indications
is given below:
Usual Adult Dose for Hypogonadism - Male:
Hypogonadotropic hypogonadism (secondary to a pituitary
deficiency):
500 to 1000 units IM three times a week for 3 weeks followed by the
same dose twice a week for 3 weeks or,
4000 units IM three times a week for 6 to 9 months followed by
2000 units three times a week for an additional 3 months.

Contraindications
➔
Eutrig-HP Injections are contraindicated in patients with a known
hypersensitivity to human gonadotropins, including hCG, or any
component of the injection.
➔
High serum FSH, indicating primary gonadal failure in women.
➔
Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid,
adrenal, or pituitary Disorders).
➔
Tumors of the hypothalamus or pituitary gland and ovary, breast, or
uterus in females and breast or prostate in males.
➔
Malformations of the reproductive organs incompatible with
pregnancy.

Contraindications
➔
Fibroid tumors of the uterus incompatible with pregnancy.
➔
Abnormal vaginal bleeding of undetermined origin
➔
Also contraindicated in cases of Precocious puberty, prostatic
carcinoma or other androgen-dependent neoplasm

Storage Instructions
Eutrig-HP Injections (Generic Human Chorionic
Gonadotrophin Injections) have to be stored at
controlled room temperature i.e. from 20°C to 25°C
(68°F to 77°F) with excursions permitted between 15°
to 30°C (59° to 86°F).
Keep this as well as all other medicines away from
children and pets.

Warnings
Human Chorionic Gonadotropin (Eutrig-HP Injections) should be used
in conjunction with human menopausal gonadotropins only by
physicians experienced with infertility problems who are familiar with
the criteria for patient selection, contraindications, warnings,
precautions, and adverse reactions described in the package insert for
menotropins.
Anaphylaxis has been reported with urinary-derived HCG products.
The principal serious adverse reactions during this use are:
(1) Ovarian hyperstimulation, a syndrome of sudden ovarian
enlargement, ascites with or without pain, and/or pleural effusion, (2)
Rupture of ovarian cysts with resultant hemoperitoneum, (3) Multiple
births, and (4) Arterial thromboembolism.

Warnings
Since infertile women undergoing assisted reproduction, and
particularly IVF, often have tubal abnormalities the incidence of ectopic
pregnancies might be increased. Early ultrasound confirmation that a
pregnancy is intrauterine is therefore important.
Prior to treating patients for inadequate endogenous stimulation of the
gonads, an examination should be performed to exclude anatomical
abnormalities of the genital organs or nongonadal endocrinopathies
(e.g. thyroid or adrenal disorders, diabetes). Primary ovarian failure
should be excluded by the determination of gonadotrophin levels.

Warnings
Patients with latent or overt cardiac failure, renal dysfunction,
hypertension, epilepsy or migraine (or a history of these
conditions) should be kept under close medical supervision,
since aggravation or recurrence may occasionally be induced as
a result of increased androgen production.
Human Chorionic Gonadotropin (Eutrig-HP Injections) should be
used cautiously in prepubertal boys to avoid premature
epiphyseal closure or precocious sexual development. Skeletal
maturation should be monitored regularly.

Possible Side Effects
Stop using Human Chorionic Gonadotropin (Eutrig-HP Injections) and get
emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or
throat. Call your doctor at once if you have any of these signs of a blood
clot: pain, warmth, redness, numbness, or tingling in your arm or leg;
confusion, extreme dizziness, or severe headache.
Common Side effects of Eutrig-HP Injections (Human Chorionic
Gonadotropin Injection) are Headache, irritability, restlessness,
depression, fatigue, edema, precocious puberty, gynecomastia, pain at
the site of injection.
Hypersensitivity reactions, both localized and systemic in nature, have
also been reported.
In rare cases generalized rash or fever may occur.

Eutrig-HP Injections Overdosage
Seek emergency medical attention if you think you have used too
much of this medicine. An overdose of HCG is not expected to produce
life-threatening symptoms.
Call your doctor right away if you have any symptoms of OHSS: severe
pelvic pain, swelling of the hands or legs, stomach pain and swelling,
shortness of breath, weight gain, diarrhea, nausea or vomiting, and
urinating less than normal.

Eutrig-HP Injections During Pregnancy
Human Chorionic Gonadotropin (Eutrig-HP Injections) is classified by the
US FDA as Pregnancy Category category X. This means that using the
medication once you are pregnant can cause birth defects in the baby. Do
not use this medication if you are pregnant. Tell your doctor right away if
you become pregnant during treatment.
Defects of forelimbs and central nervous system and alterations in sex
ratio have been reported in mice receiving combined Gonadotropin and
Chorionic Gonadotropin therapy in dosages to induce superovulation.
Multiple ovulations with resulting plural gestations (mostly twins) have
been reported to occur in approximately 20% of pregnancies when
conception has followed Chorionic Gonadotropin therapy.

Eutrig-HP Injections During Nursing
It is not known whether Chorionic Gonadotropin (Eutrig-HP)
is excreted in human milk. Since many medicines are
excreted in human milk, caution should be exercised when
Chorionic Gonadotropin is administered to a nursing
woman.

Eutrig-HP Injections (Generic Human Chorionic
Gonadotrophin Injections) are manufactured by
Samarth Life Sciences Private Limited, India.

Eutrig-HP Injections (Generic Human Chorionic Gonadotrophin Injections)

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