Valclovir Tablets (Generic Valacyclovir Hydrochloride 500 mg and 1000 mg Tablets) belongs to a group of medications called antivirals. Valclovir can be used to: treat shingles (in adults), treat HSV infections of the skin and genital herpes (in adults and adolescents over 12 years old). It is also used to help prevent these infections from returning. Generic Valacyclovir tablets is also used to treat cold sores (in adults and adolescents over 12 years old), prevent infection with CMV after organ transplants (in adults and adolescents over 12 years old) and treat and prevent HSV infections of the eye that continue to come back (in adults and adolescents over 12 years old). This medicine works by killing or stopping the growth of viruses called herpes simplex (HSV), varicella zoster (VZV) and cytomegalovirus (CMV).

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets (Generic Valacyclovir Hydrochloride 500 mg
and 1000 mg Tablets) belongs to a group of medications called
antivirals. Valclovir can be used to: treat shingles (in adults),
treat HSV infections of the skin and genital herpes (in adults and
adolescents over 12 years old). It is also used to help prevent
these infections from returning. Generic Valacyclovir tablets is
also used to treat cold sores (in adults and adolescents over 12
years old), prevent infection with CMV after organ transplants (in
adults and adolescents over 12 years old) and treat and prevent
HSV infections of the eye that continue to come back (in adults
and adolescents over 12 years old). This medicine works by
killing or stopping the growth of viruses called herpes simplex
(HSV), varicella zoster (VZV) and cytomegalovirus (CMV).

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Active Ingredient
The active ingredient contained in Valclovir tablets is
Valacyclovir Hydrochloride.
Each film-coated Valclovir tablet contains Valacyclovir
Hydrochloride equivalent to 500 mg or 1000 mg of Valacyclovir
respectively.

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Chemical Structure
The structure of Valacyclovir Hydrochloride is given below:

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) are
manufactured by Healing Pharma India Private Limited in the
strengths of 500 mg and 1000 mg.
( Website: https://www.healingpharma.in/ )
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valacyclovir Hydrochloride Tablets – Brand Names
Valacyclovir Hydrochloride tablets are
available under various drug trade names
that include Valclovir, Centrex,
Valtrex,Valcivir, Valamac and Valavir.

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Uses of Valclovir 500 mg and 1000 mg Tablets
Valclovir tablets (Generic Valacyclovir Hydrochloride tablets) is
used to treat herpes virus infections, including herpes labialis
(also known as cold sores), herpes zoster (also known as
shingles), and herpes simplex (also known as genital herpes) in
adults. It is also used to treat chickenpox and cold sores in
children.
In your body, Valacyclovir becomes the anti-herpes medicine,
Acyclovir. Although Valacyclovir will not cure shingles or genital
herpes, it does help relieve the pain and discomfort and helps
the sores heal faster.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Dosage
The dosage of Valclovir tablets (Generic Valacyclovir
Hydrochloride Tablets) is given below:
Treatment of Cold Sores (Herpes Labialis) in Adults: The
recommended dosage of Valclovir tablets for treatment of cold
sores is 2 grams twice daily for 1 day taken 12 hours apart.
Treatment should be started at the earliest symptom of a cold sore
(e.g., tingling, itching, or burning).
Treatment of Genital Herpes in Adults: Initial Episode: The
recommended dosage of Valclovir tablets for treatment of initial
genital herpes is 1 gram twice daily for 10 days. Therapy was most
effective when administered within 48 hours of the onset of signs
and symptoms.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Dosage
The dosage of Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets)
is given below:
Treatment of Genital Herpes in Adults: Recurrent Episodes: The
recommended dosage of Valclovir tablets for treatment of recurrent genital
herpes is 500 mg twice daily for 3 days. Initiate treatment at the first sign or
symptom of an episode.
Suppressive Therapy: The recommended dosage of Valclovir tablets for
chronic suppressive therapy of recurrent genital herpes is 1 gram once daily in
patients with normal immune function. In patients with a history of 9 or fewer
recurrences per year, an alternative dose is 500 mg once daily.
In HIV-infected patients with a CD4+ cell count greater than or equal to 100
cells/mm3, the recommended dosage of Valacyclovir Hydrochloride for
chronic suppressive therapy of recurrent genital herpes is 500 mg twice daily.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Dosage
The dosage of Valclovir tablets (Generic Valacyclovir Hydrochloride
Tablets) is given below:
Reduction of Transmission: The recommended dosage of Valclovir
tablets for reduction of transmission of genital herpes in patients with a
history of 9 or fewer recurrences per year is 500 mg once daily for the
source partner.
Treatment of Herpes Zoster in Adults: The recommended dosage of
Valclovir tablets for treatment of herpes zoster is 1 gram 3 times daily for
7 days. Therapy should be initiated at the earliest sign or symptom of
herpes zoster and is most effective when started within 48 hours of the
onset of rash.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Dosage
The dosage of Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets)
is given below:
Pediatric Dosing Recommendations: Cold Sores (Herpes Labialis): The
recommended dosage Of Valacyclovir Hydrochloride tablets for the treatment
of cold sores in pediatric patients greater than or equal to 12 years of age is 2
grams twice daily for 1 day taken 12 hours apart. Therapy should be initiated at
the earliest symptom of a cold sore (e.g., tingling, itching, or burning).
Chickenpox: The recommended dosage of Valacyclovir Hydrochloride tablets
for treatment of chickenpox in immunocompetent pediatric patients 2 to less
than 18 years of age is 20 mg/kg administered 3 times daily for 5 days. The
total dose should not exceed 1 gram 3 times daily. Theatment must be initiated
at the earliest sign or symptom.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Contraindications
Valclovir tablets are contraindicated in patients with a
hypersensitivity to Valacyclovir Hydrochloride (e.g., anaphylaxis),
Acyclovir, or any other component of this medication.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Storage Instructions
Valclovir tablets (Generic Valacyclovir
Hydrochloride tablets) have to be stored at
controlled room temperature i.e. from 20°C
to 25°C (68°F to 77°F) with excursions
permitted between 15° to 30°C (59° to 86°F).
Keep this as well as all other medicines
away from children and pets.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Warnings
Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome
(TTP/HUS): Has occurred in patients with advanced HIV disease and in
allogenic bone marrow transplant and renal transplant patients
receiving 8 grams per day of Generic Valacyclovir in clinical trials.
Discontinue treatment if clinical symptoms and laboratory findings
consistent with TTP/HUS occur.
Acute renal failure: May occur in elderly patients (with or without
reduced renal function), patients with underlying renal disease who
receive higher than recommended doses of Generic Valacyclovir for
their level of renal function, patients who receive concomitant
nephrotoxic drugs, or inadequately hydrated patients. Use with caution
in elderly patients and reduce dosage in patients with renal
impairment.

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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Warnings
Central nervous system adverse reactions (e.g., agitation,
hallucinations, confusion, and encephalopathy): May occur in
elderly patients (with or without reduced renal function) and in
patients with underlying renal disease who receive higher than
recommended doses of Generic Valacyclovir for their level of
renal function. Use with caution in elderly patients and reduce
dosage in patients with renal impairment.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets Side Effects
The most common Valacyclovir Hydrochloride(Valclovir tablets)
side effects reported in at least 1 indication by greater than 10% of
adult subjects treated with Valacyclovir Hydrochloride and
observed more frequently with Valacyclovir Hydrochloride
compared with placebo are headache, nausea, and abdominal
pain.
The only adverse reaction reported in greater than 10% of
pediatric subjects aged less than 18 years was headache.
The serious side effects include: Thrombotic Thrombocytopenic
Purpura/Hemolytic Uremic Syndrome, Acute Renal Failure and
Central Nervous System Effects.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Overdose
Caution should be exercised to prevent inadvertent
Valacyclovir Hydrochloride(Valclovir tablets) overdose.
Precipitation of Acyclovir in renal tubules may occur when
the solubility (2.5 mg/mL) is exceeded in the intratubular
fluid. In the event of acute renal failure and anuria, the
patient may benefit from hemodialysis until renal function
is restored.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
Valclovir Tablets During Pregnancy
Valacyclovir Hydrochloride (Valclovir tablets) has been classified by
the US FDA as Pregnancy Category B.
There are no adequate and well-controlled studies of Valacyclovir
tablets or Acyclovir in pregnant women.
Animal reproduction studies performed at oral doses that provided up to
10 and 7 times the human plasma levels during the period of major
organogenesis in rats and rabbits, respectively, revealed no evidence of
teratogenicity.
Based on pregnancy registry data the overall rate of birth defects in
infants exposed to Acyclovir in- utero appears similar to the rate for
infants in the general population. Valclovir tablets must be used during
pregnancy only if the potential benefit justifies the potential risk to the
foetus.
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Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)
For more details on
Valclovir Tablets click here
Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) by
Healing Pharma India Private Limited.
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