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Lesson Objectives
• Define and state:
– Aerobic Respiration
– Anaerobic Respiration
• Describe the effect of lactic acid in muscles
during exercise
What is Respiration?
Respiration Breathing
Inhaling & Exhaling
???
Digestion & Absorption
Starch
Maltose
Glucose
Absorbed into the
blood stream
Respiration
Glucose
ATP
Uptake of glucose
into cells
• Muscular Contraction
• Protein Synthesis
• Cell Division
• Transmission of Nerve Impulses
• Heat Generation
What do we use the ENERGY for?
Did You Know That?!
Your brain cells need 2X more
energy than other cells in the body
Adapted from- The Franklin Institute Online
Respiration
What do they mean?
• Word Equation
Glucose Oxygen
Carbon
Dioxide Water
Large
amount
of Energy
Definition:
Complete oxidation (breakdown) of food substances
that occur in the presence of oxygen, with the release
of large amount of energy.
Carbon dioxide and water produced as waste products.
• Word Equation (In human muscle cells)
Glucose Small amount
of Energy
Lactic
Acid
Definition:
Incomplete breakdown (oxidation) of food substances
that occur in the absence of oxygen, with the release
of small amount of energy
Lactic acid produced as waste products.
Have you ever wondered...
Why do we feel
our muscles
‘burning’ when
we exercise too
vigorously
-Aerobic Respiration
-Anaerobic Respiration
What’s going on in our body??
At rest
rest
Oxygenuptake
Time(min)
Oxygen uptake
Lactic acid in blood plasma
Normal metabolic rate
Lacticacidin
bloodplasma
0 5 15 20 30 45
What’s going on in our body??
rest exercise
Oxygenuptake
Time(min)
Oxygen uptake
Lactic acid in blood plasma
Initial stage of exercise
Normal metabolic rate
Lacticacidin
bloodplasma
0 5 15 20 30 45
What’s going on in our body??
rest exercise
Oxygenuptake
Time(min)
Oxygen uptake
Lactic acid in blood plasmaplateau stage
Normal metabolic rate
Lacticacidin
bloodplasma
0 5 15 20 30 45
What’s going on in our body??
rest exercise
Oxygenuptake
Time(min)
Oxygen uptake
Lactic acid in blood plasmaplateau stage
Normal metabolic rate
Lacticacidin
bloodplasma
0 5 15 20 30 45
Anaerobic Respiration
What’s going on in our body??
rest exercise recovery
Oxygenuptake
Time(min)
Oxygen uptake
Lactic acid in blood plasmaRecovery stage
Normal metabolic rate
Lacticacidin
bloodplasma
0 5 15 20 30 45
Anaerobic Respiration
Why is lactic acid formed during
vigorous exercise?
Vigorous muscular contraction
Muscles need to respire more
to release more energy
(Glucose + O2 CO2 +
H20 + ↑Energy)
More glucose and oxygen
needed for respiration
Heart pumps faster to
circulate blood around
the body at a faster rate
Increase build-up of CO2
Panting to remove carbon dioxide
& take in oxygen at a faster rate
Insufficient oxygen to meet the
vigorous muscular contraction
Anaerobic respiration occurs in
muscles cells, and lactic acid is
produced
During recovery, lactic acid is
transported to the liverConverted to glucose/ energy
10.3
Experiments to investigate
respiration
• The potassium hydroxide in flask A removes carbon
dioxide from the air entering flask B.
• The limewater in flask B should not turn chalky.
• The air entering flask C does not contain carbon dioxide.
Hence, any carbon dioxide detected in flask D would be
due to respiration by the snails.
Carbon dioxide is a product of respiration
potassium
hydroxide solution
limewater limewatersnails
A B C D
Studying Respiration10.3
• The glucose solution that is used was
first boiled and cooled prior to addition
of the yeast cells. Boiling removed the
dissolved oxygen from the solution.
• Due to the limited oxygen available to
the yeast, the yeast undergoes
anaerobic respiration.
• If carbon dioxide is released during the
anaerobic respiration of yeast, the
limewater will turn chalky. limewaterglucose and yeast
suspension
Carbon dioxide is a product of respiration
Studying Respiration10.3
vacuum
flask
pea seeds
in antiseptic
solution
thermometer
cotton wool
plug
• The vacuum flask prevents heat from
escaping and entering the area where
the seeds are germinating.
• The cotton wool plug allows gaseous
exchange between the seeds and the
environment.
• The antiseptic solution prevents the
growth of microorganisms like bacteria.
• If heat is produced during respiration,
the thermometer would register a
temperature higher than the surrounding
temperature.
Heat is a product of respiration
Studying Respiration10.3
Gaseous Exchange
Label the parts that involves in breathing
Human Gas Exchange System
1. Air enters through the nose or the mouth
larynx
pharynx
2. Air moves down the trachea
larynx
pharynx
trachea
3. Air enters the left and right bronchi & into the
bronchioles
larynx
pharynx
trachea
bronchi
bronchioles
4. Air enters the alveoli
larynx
pharynx
trachea
bronchi
bronchioles
alveoli
Aaahhh-Choooo!!!!
What is in there?!
Mucus
Imagine life without mucus
Gland Cells & Ciliated Cells
Gland Cell
Ciliated
Cells
4. Air enters the alveoli
larynx
pharynx
trachea
bronchi
bronchioles
Alveoli
Alveolus
Adaptation of Alveolus for Gaseous
Exchange
CO₂
O₂O₂
1 cell thick
alveolar wall
Thin film of
moisture
Blood
capillary
Oxyhaemoglobin
Alveoli
Adaptation of Alveoli: Functions:
a) Numerous alveoli To provide a very large surface area for
gas exchange
a) One-cell thick wall
of blood capillary
and alveolar wall
To allow for rapid diffusion of gases
a) A film of moisture
on inner alveolar
surface
To allow for oxygen to dissolve in it
a) Densely
surrounded by
blood capillaries
To maintain a steep concentration gradient
for continuous flow of gases through
diffusion between blood and alveoli
10.4
Breathing
Mechanism
Pure
Demonstration
Diaphragm
Relaxed
Glass tube
(bronchus)
Rubber sheet
(diaphragm)
Glass tube
(trachea)
Balloons
(lungs)
Bell jar
(thoracic cavity)
Pure
What happens when the rubber sheet is pulled down?
Predict the observations:
• Volume of space in bell jar
increases.
• Air pressure in bell jar
decreases.
• Atmospheric pressure is now
higher than the air pressure
inside.
• Air is forced into the balloons
through the tube.
10.4
Pure
Volume of thorax increases:
• Pressure in thorax drops
•Atmospheric pressure (outside) > Thorax Pressure (inside)
External Intercostal
Muscles Contract
Internal Intercostal
Muscles Relax
Ribs swing upwards and outwards
Diaphragm contracts, pulling it down into a flattened shape
Air is forced into the lung.
Inspiration/Inhalation10.4
Pure
Volume of thorax decreases:
• Pressure in thorax __________.
•Atmospheric pressure (outside) < Thorax Pressure (inside)
External Intercostal
Muscles _________.
Internal Intercostal
Muscles __________.
Ribs returns to original positions.
Diaphragm _________ and moves __________.
Air is forced ______ of the lung.
Expiration/ Exhalation
relax contract
relaxed upwards
increases
out
10.4
Pure
Inspiration
Component of inspired air
• 21% oxygen
• 0.03 % carbon dioxide
• 1% other gases
• 78% nitrogen
• Variable (water vapour
and dust)
• Lower temperature
10.4
Pure
Expiration
Component of expired air
• 16% oxygen
• 4% carbon dioxide
• 1% other gases
• 78% nitrogen
• Saturated water vapour.
• Higher temperature.
• No dust particle / little
10.4
Pure
(1) During inhalation, the air that enters the lungs
causes the lung to expand.
* During inhalation, the volume of the
thoracic cavity increases, resulting in
a drop in pressure.
The higher atmospheric air pressure
causes air to rush in.
Pure
4. Air enters the alveoli
larynx
pharynx
trachea
bronchi
bronchioles
Alveoli
Alveolus
10.6
How is carbon dioxide transported
around the body?
Pure
• As the tissues undergo aerobic
respiration, carbon dioxide produced
diffuse into the blood and enters into
the red blood cells.
• In the red blood cell, enzyme
carbonic anhydrase are present to
catalyse carbon dioxide and water
to form carbonic acid.
• Carbonic acid is then converted into
hydrogencarbonate ions, HCO3
-,
which then diffuses out of the red
blood cells.
• Most of the carbon dioxide is
transported as hydrogencarbonate
ions in the blood plasma.
10.6
Pure
In the lung, hydrogencarbonate ions ,HCO3
-
diffuse back into the red blood cell, where they are
converted back into carbonic acid, and then carbon
dioxide and water by enzyme carbonic anhydrase.
Carbon dioxide diffuses out of blood capillaries into
the alveoli, and is expelled out when you breathe
out.
10.6
Pure
What’s Wrong!?
Effects of Smoking on the Respiratory System
Carbon
Monoxide
Tar
Nicotine
Effects of Tobacco Smoke
Nicotine
Stimulate
adrenaline release
↑ Heartbeat &
Blood Pressure
(Your heart works
harder)
Makes blood clot
easily
↑ Risk of blood
clots
Effects of Tobacco Smoke
Carbon
Monoxide
Combines with
Haemoglobin
(Irreversibly)
Forms
carboxyhaemoglobin,
↓ O₂ Transport
↑ rate of fatty
deposit in inner
arterial wall
↑ Risk of coronary
heart disease
Effects of Tobacco Smoke
Tar
Carcinogenic
(Cancer causing)
↑ risk of lung cancer
Paralyses cilia of air
passages
Blockage in air sacs
and ↓ gas exchange
efficiency
Did You Know That?!
46,000 non-smoking Americans die of
heart disease due to 2nd hand smoke!!
Diseases caused by smoking
1. Chronic Bronchitis (Long Term)
2. Emphysema
3. Lung Cancer
Emphysema
•Due to persistent violent coughing
 lead to breakdown of alveolar wall
•Experience difficulty in breathing
Chronic Bronchitis
• Particles in tobacco smoke can cause chronic
bronchitis
– Excessive mucus secreted to trap particles
– But, paralysed cilia cannot function normally
– Airway become blocked
Chronic Bronchitis
Gland Cell
Ciliated
Cells
Chronic Bronchitis
Lung Cancer
Apart from lung
cancer, cancers
of the mouth,
throat, pancreas
kidneys and
urinary bladder
are also increased
62

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Respiration

  • 1.
  • 2. Lesson Objectives • Define and state: – Aerobic Respiration – Anaerobic Respiration • Describe the effect of lactic acid in muscles during exercise
  • 3. What is Respiration? Respiration Breathing Inhaling & Exhaling ???
  • 6. • Muscular Contraction • Protein Synthesis • Cell Division • Transmission of Nerve Impulses • Heat Generation What do we use the ENERGY for?
  • 7. Did You Know That?! Your brain cells need 2X more energy than other cells in the body Adapted from- The Franklin Institute Online
  • 9. • Word Equation Glucose Oxygen Carbon Dioxide Water Large amount of Energy Definition: Complete oxidation (breakdown) of food substances that occur in the presence of oxygen, with the release of large amount of energy. Carbon dioxide and water produced as waste products.
  • 10. • Word Equation (In human muscle cells) Glucose Small amount of Energy Lactic Acid Definition: Incomplete breakdown (oxidation) of food substances that occur in the absence of oxygen, with the release of small amount of energy Lactic acid produced as waste products.
  • 11. Have you ever wondered... Why do we feel our muscles ‘burning’ when we exercise too vigorously
  • 13. What’s going on in our body?? At rest rest Oxygenuptake Time(min) Oxygen uptake Lactic acid in blood plasma Normal metabolic rate Lacticacidin bloodplasma 0 5 15 20 30 45
  • 14. What’s going on in our body?? rest exercise Oxygenuptake Time(min) Oxygen uptake Lactic acid in blood plasma Initial stage of exercise Normal metabolic rate Lacticacidin bloodplasma 0 5 15 20 30 45
  • 15. What’s going on in our body?? rest exercise Oxygenuptake Time(min) Oxygen uptake Lactic acid in blood plasmaplateau stage Normal metabolic rate Lacticacidin bloodplasma 0 5 15 20 30 45
  • 16. What’s going on in our body?? rest exercise Oxygenuptake Time(min) Oxygen uptake Lactic acid in blood plasmaplateau stage Normal metabolic rate Lacticacidin bloodplasma 0 5 15 20 30 45 Anaerobic Respiration
  • 17. What’s going on in our body?? rest exercise recovery Oxygenuptake Time(min) Oxygen uptake Lactic acid in blood plasmaRecovery stage Normal metabolic rate Lacticacidin bloodplasma 0 5 15 20 30 45 Anaerobic Respiration
  • 18. Why is lactic acid formed during vigorous exercise?
  • 19. Vigorous muscular contraction Muscles need to respire more to release more energy (Glucose + O2 CO2 + H20 + ↑Energy) More glucose and oxygen needed for respiration Heart pumps faster to circulate blood around the body at a faster rate Increase build-up of CO2 Panting to remove carbon dioxide & take in oxygen at a faster rate Insufficient oxygen to meet the vigorous muscular contraction Anaerobic respiration occurs in muscles cells, and lactic acid is produced During recovery, lactic acid is transported to the liverConverted to glucose/ energy
  • 21. • The potassium hydroxide in flask A removes carbon dioxide from the air entering flask B. • The limewater in flask B should not turn chalky. • The air entering flask C does not contain carbon dioxide. Hence, any carbon dioxide detected in flask D would be due to respiration by the snails. Carbon dioxide is a product of respiration potassium hydroxide solution limewater limewatersnails A B C D Studying Respiration10.3
  • 22. • The glucose solution that is used was first boiled and cooled prior to addition of the yeast cells. Boiling removed the dissolved oxygen from the solution. • Due to the limited oxygen available to the yeast, the yeast undergoes anaerobic respiration. • If carbon dioxide is released during the anaerobic respiration of yeast, the limewater will turn chalky. limewaterglucose and yeast suspension Carbon dioxide is a product of respiration Studying Respiration10.3
  • 23. vacuum flask pea seeds in antiseptic solution thermometer cotton wool plug • The vacuum flask prevents heat from escaping and entering the area where the seeds are germinating. • The cotton wool plug allows gaseous exchange between the seeds and the environment. • The antiseptic solution prevents the growth of microorganisms like bacteria. • If heat is produced during respiration, the thermometer would register a temperature higher than the surrounding temperature. Heat is a product of respiration Studying Respiration10.3
  • 25. Label the parts that involves in breathing
  • 27. 1. Air enters through the nose or the mouth larynx pharynx
  • 28. 2. Air moves down the trachea larynx pharynx trachea
  • 29. 3. Air enters the left and right bronchi & into the bronchioles larynx pharynx trachea bronchi bronchioles
  • 30. 4. Air enters the alveoli larynx pharynx trachea bronchi bronchioles alveoli
  • 33. Gland Cells & Ciliated Cells Gland Cell Ciliated Cells
  • 34. 4. Air enters the alveoli larynx pharynx trachea bronchi bronchioles Alveoli Alveolus
  • 35. Adaptation of Alveolus for Gaseous Exchange CO₂ O₂O₂ 1 cell thick alveolar wall Thin film of moisture Blood capillary Oxyhaemoglobin
  • 36. Alveoli Adaptation of Alveoli: Functions: a) Numerous alveoli To provide a very large surface area for gas exchange a) One-cell thick wall of blood capillary and alveolar wall To allow for rapid diffusion of gases a) A film of moisture on inner alveolar surface To allow for oxygen to dissolve in it a) Densely surrounded by blood capillaries To maintain a steep concentration gradient for continuous flow of gases through diffusion between blood and alveoli
  • 38. Demonstration Diaphragm Relaxed Glass tube (bronchus) Rubber sheet (diaphragm) Glass tube (trachea) Balloons (lungs) Bell jar (thoracic cavity) Pure
  • 39. What happens when the rubber sheet is pulled down? Predict the observations: • Volume of space in bell jar increases. • Air pressure in bell jar decreases. • Atmospheric pressure is now higher than the air pressure inside. • Air is forced into the balloons through the tube. 10.4 Pure
  • 40. Volume of thorax increases: • Pressure in thorax drops •Atmospheric pressure (outside) > Thorax Pressure (inside) External Intercostal Muscles Contract Internal Intercostal Muscles Relax Ribs swing upwards and outwards Diaphragm contracts, pulling it down into a flattened shape Air is forced into the lung. Inspiration/Inhalation10.4 Pure
  • 41. Volume of thorax decreases: • Pressure in thorax __________. •Atmospheric pressure (outside) < Thorax Pressure (inside) External Intercostal Muscles _________. Internal Intercostal Muscles __________. Ribs returns to original positions. Diaphragm _________ and moves __________. Air is forced ______ of the lung. Expiration/ Exhalation relax contract relaxed upwards increases out 10.4 Pure
  • 42. Inspiration Component of inspired air • 21% oxygen • 0.03 % carbon dioxide • 1% other gases • 78% nitrogen • Variable (water vapour and dust) • Lower temperature 10.4 Pure
  • 43. Expiration Component of expired air • 16% oxygen • 4% carbon dioxide • 1% other gases • 78% nitrogen • Saturated water vapour. • Higher temperature. • No dust particle / little 10.4 Pure
  • 44. (1) During inhalation, the air that enters the lungs causes the lung to expand. * During inhalation, the volume of the thoracic cavity increases, resulting in a drop in pressure. The higher atmospheric air pressure causes air to rush in. Pure
  • 45. 4. Air enters the alveoli larynx pharynx trachea bronchi bronchioles Alveoli Alveolus
  • 46. 10.6 How is carbon dioxide transported around the body? Pure
  • 47. • As the tissues undergo aerobic respiration, carbon dioxide produced diffuse into the blood and enters into the red blood cells. • In the red blood cell, enzyme carbonic anhydrase are present to catalyse carbon dioxide and water to form carbonic acid. • Carbonic acid is then converted into hydrogencarbonate ions, HCO3 -, which then diffuses out of the red blood cells. • Most of the carbon dioxide is transported as hydrogencarbonate ions in the blood plasma. 10.6 Pure
  • 48. In the lung, hydrogencarbonate ions ,HCO3 - diffuse back into the red blood cell, where they are converted back into carbonic acid, and then carbon dioxide and water by enzyme carbonic anhydrase. Carbon dioxide diffuses out of blood capillaries into the alveoli, and is expelled out when you breathe out. 10.6 Pure
  • 49. What’s Wrong!? Effects of Smoking on the Respiratory System
  • 51. Effects of Tobacco Smoke Nicotine Stimulate adrenaline release ↑ Heartbeat & Blood Pressure (Your heart works harder) Makes blood clot easily ↑ Risk of blood clots
  • 52. Effects of Tobacco Smoke Carbon Monoxide Combines with Haemoglobin (Irreversibly) Forms carboxyhaemoglobin, ↓ O₂ Transport ↑ rate of fatty deposit in inner arterial wall ↑ Risk of coronary heart disease
  • 53. Effects of Tobacco Smoke Tar Carcinogenic (Cancer causing) ↑ risk of lung cancer Paralyses cilia of air passages Blockage in air sacs and ↓ gas exchange efficiency
  • 54. Did You Know That?! 46,000 non-smoking Americans die of heart disease due to 2nd hand smoke!!
  • 55. Diseases caused by smoking 1. Chronic Bronchitis (Long Term) 2. Emphysema 3. Lung Cancer
  • 56. Emphysema •Due to persistent violent coughing  lead to breakdown of alveolar wall •Experience difficulty in breathing
  • 57. Chronic Bronchitis • Particles in tobacco smoke can cause chronic bronchitis – Excessive mucus secreted to trap particles – But, paralysed cilia cannot function normally – Airway become blocked
  • 60. Lung Cancer Apart from lung cancer, cancers of the mouth, throat, pancreas kidneys and urinary bladder are also increased 62