Cholesterol (Chemistry of Lipids - V) Chemistry, Structure, Properties of Triacylglycerols.

1. CH3
Cholesterol AshokKatta

2. CH3
Cholesterol is
the major
sterol in
animal tissues.
No vegetable
oil contains
any
cholesterol
Only a little
portion of the
body
cholesterol is
derived from
diet.
The bulk of it
is synthesized
in the body.
Cholesterol AshokKatta

3. CH3
 It has the ring called
cyclopentanoperhydrophenanthrene (CPPP) as a
parent structure.
OH
A B
C D
Cholesterol AshokKatta

4. CH3
Cholesterol AshokKatta

5. Functions of Cholesterol
Cholesterol AshokKatta

6. CH3
When phospholipids are
distributed in water, their
hydrophobic parts keep
away from water, forming
molecular aggregates called
micelle
These are involved in
solubilization of lipids in
aqueous media and help in
digestion and absorption of
lipids.
Cholesterol AshokKatta

7. CH3
A lipid bilayer will close
on itself under
appropriate conditions
to form liposomes.
They may be prepared by
sonication of mixtures of
phospholipids and
cholesterol
Cholesterol AshokKatta

8. Cholesterol AshokKatta

9. 9
Cholesterol AshokKatta