A polypeptide chain contains an amphipathic helix, with arginine and lysine residues on one side and hydrophobic residues on the other. It will likely enter: the peroxisome. ria. the ER. the lysosome. the mitochondriaa. the peroxisome. ria.b. the ER.c. the lysosome.d. the mitochondria Solution Amphipathic protein chain has positive amino residues at one end and negative amino residues at other end. This arrangement, that acts as signal sequence, is recognised by specific receptors present on mitochondrial membrane ,for protein precursors transloation from cytosol. So Answer is D: Mitochondria.