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Which of the following enzymes has the ability to accomplish all three of the following: 1) cut
DNA; 2) introduce and/or remove twists in the molecule; and 3) rejoin the cut ends of a DNA
molecule?Restriction enzymeType I TopoisomeraseDNase IType II Topoisomerase
Solution
Answer:
The type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA,
relax the strand, and reanneal the strand. They are further subdivided into two structurally and
mechanistically distinct topoisomerases: type IA and type IB.Type I Topoisomerase

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