Compare and contrast the thick and thin filaments.SolutionTher.pdf

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Compare and contrast the thick and thin filaments. Solution There are two different types of filaments that extend along the muscle tissues in cylindrical shapes. Together these two filaments are known as myofibrils. Thick Filaments: 1. Myosin(a large family of motor protein ) are found to be present in these thick filaments in a bipolar fashion 2. These filaments can be found in one of the bands of sarcomere (skeletal muscle tissue) called A-Band (anisotropic band named after its property to be directionally dependent unlike isotropy ) 3. These filaments are divided/separated by an M-Line which is made up of myomesin protein Thin Filaments 1.Unlike thick filaments, thin filaments are made up of 3 types of proteins (actin, tropomyosin, and troponin) while troponin and tropomyosin are engaged is muscle contraction, actin is engaged in cell shape and cell adhesion. 2. Thin filaments are present in both A-Band and I-Band (While A-Band is anisotropic due to its quality of being directionally dependent, I-Band is isotropic band being directionally independent 3. It is divided by a different proteinaceous non-contractile line called Z-Line.

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OVERVIEW Muscle is a tissue characterized by irritability and contractility. It is composed of elongated cells called myocytes that contain contractile proteins organized as cytoplasmic filaments. Muscle cells are attached to bones and soft tissues, and thereby accomplish mechanical movements as a consequence of their contraction (shortening). Traditionally, three types of muscle tissue are recognized: skeletal, cardiac, and smooth. Skeletal and cardiac muscle are classified as striated muscles based on the appearance of striations that run perpendicular to the long axis of the cells. The striations are due to a highly ordered, repetitive organization of two filamentous contractile proteins - actin and myosin, which are arranged into thin and thick filaments, respectively. Smooth muscle lacks striations due to a less structured, looser arrangement of its contractile filaments. In muscle terminology, the sarcolemma refers to the muscle cell membrane, the sarcoplasm refers to the cytoplasm, and the sarcoplasmic reticulum refers to the smooth endoplasmic reticulum.

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Muscle organization and structure Characteristics of muscle - give specific example of each of those terms Kinds of muscle - overall, know skeletal in and out. Know basics of cardiac and smooth, esp in compare/contrast with skel or in a way that makes it work the best organization and hierarchy of macro to micro structures Larger to smaller bundles, wrapped in own sheath Muscle fibers - organization and function of these components sarcoplasm (surrounds/contains mitos, nuclei, glycogen, myoglobin) Myofibril Sarcomere - thick and thin filaments, actin, troponin, tropomyosin, myosin, Z disk. RELATED TO LAB: ID kinds of muscle and what the light/dark bands are Triad - T tubules, SR and Terminal cisternae - WHY IS THIS IMPORTANT? Electrophys basics Voltage - what is it, how does it relate to membrane? Electrochem gradients - be able to predict direction ion would flow given vm and E(ion) Finish elcetrophys basics, start muscle contraction Electrophys basics Electrochem gradients - be able to predict direction ion would flow given vm and E(ion). Know WHAT Nernst is used for and what the important values are for calculation concentrations in and out), but don\'t memorize equation; won\'t be asked to use it. Movement of ions Ion channels Different kinds, stimuli to open Pumps - active Why is Na/K super important? (and, later, why would Ca pump back into SR be super important?) Again: Voltage - what is it, how does it relate to membrane? AP v at rest v Equilib potential (and later, post synaptic potential) NMJ and Steps to muscle contraction - Understand organization and how all the parts work together. We went really into depth here; fair to expect some fluency with it. To test yourself, think about what would happen if you messed with individual components, ion channels, signaling molecules. Axon terminal ACh (and -esterase) Synapse Post-synaptic receptors and junctional folds Sarcomere - thick and thin filaments, actin, troponin, tropomyosin, myosin, Z disk. RELATED TO LAB: ID kinds of muscle and what the light/dark bands are Triad - T tubules, SR and Terminal cisternae - WHY IS THIS IMPORTANT? Muscle contraction, con\'t - see Week 5 Write! Fluent in the major steps - what changes concentration, shape/length, moves, binds Solution The questions are huge and broad, I have tried to answer some. Kinds of Muscles There are three types of muscle - Skeletal, smooth and cardiac. Skeletal muscle is attached to bones and moves and supports the skeleton. Smooth muscle surrounds hollow cavities and tubes. Cardiac muscle is the muscle of the heart. Structure of skeletal muscles The most striking feature seen when observing a muscle fiber through a light microscope is a series of light and dark bands perpendicular to the long axis of the fiber. Both skeletal- and cardiac- muscle fibers have this characteristic banding and are known as striated muscles. Smooth muscles do not show banding pattern. The striated pattern in skeletal and cardiac fibers results from .

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Program In C You are required to write an interactive C program that.pdf

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Prove that is L is regular and h is a homomorphism, then h(L) is regular. Prove that is L is regular and h is a homomorphism, then h(L) is regular. Prove that is L is regular and h is a homomorphism, then h(L) is regular. Solution If L is a regular language, and h is a homomorphism on its alphabet, then h(L) = {h(w) | w is in L} is also a regular language. Proof : Let E be a regular expression for L. Apply h to each symbol in E. Language of resulting RE is h(L). Let h(0) = ab; h(1) = .Let L be the language of regular expression 01* +10*. Then h(L) is the language of regular expression ab* +(ab)*. which can be simplified * = , so ab*=ab is the identitiy under concetenation . so E=E=E for any RE E Thus ab*+(ab)* =ab +(ab)* =ab+(ab)* Finall , L(ab) is contained in L(ab)* so RE for h(L) is (ab)* so h(L) is regular.

Prove that is L is regular and h is a homomorphism, then h(L) is.pdf

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Not sure how to do this case analysis please help me do it! 1.Are the regions similar? 2.What would be a good forecasting method to use? 3.Are there more advanced methods that might be considered? Here is the data https://docs.google.com/spreadsheets/d/1LYZHLx9f0Av9FJ6NLfULMU61cZPV3voqrVzbJNfV jKk/edit?usp=sharing Solution Most people view the world as consisting of a large number of alternatives. Futures research evolved as a way of examining the alternative futures and identifying the most probable. Forecasting is designed to help decision making and planning in the present. Forecasts empower people because their use implies that we can modify variables now to alter (or be prepared for) the future. A prediction is an invitation to introduce change into a system. There are several assumptions about forecasting: 1. There is no way to state what the future will be with complete certainty. Regardless of the methods that we use there will always be an element of uncertainty until the forecast horizon has come to pass. 2. There will always be blind spots in forecasts. We cannot, for example, forecast completely new technologies for which there are no existing paradigms. 3. Providing forecasts to policy-makers will help them formulate social policy. The new social policy, in turn, will affect the future, thus changing the accuracy of the forecast. Many scholars have proposed a variety of ways to categorize forecasting methodologies. The following classification is a modification of the schema developed by Gordon over two decades ago: Genius forecasting - This method is based on a combination of intuition, insight, and luck. Psychics and crystal ball readers are the most extreme case of genius forecasting. Their forecasts are based exclusively on intuition. Science fiction writers have sometimes described new technologies with uncanny accuracy. There are many examples where men and women have been remarkable successful at predicting the future. There are also many examples of wrong forecasts. The weakness in genius forecasting is that its impossible to recognize a good forecast until the forecast has come to pass. Some psychic individuals are capable of producing consistently accurate forecasts. Mainstream science generally ignores this fact because the implications are simply to difficult to accept. Our current understanding of reality is not adequate to explain this phenomena. Trend extrapolation - These methods examine trends and cycles in historical data, and then use mathematical techniques to extrapolate to the future. The assumption of all these techniques is that the forces responsible for creating the past, will continue to operate in the future. This is often a valid assumption when forecasting short term horizons, but it falls short when creating medium and long term forecasts. The further out we attempt to forecast, the less certain we become of the forecast. The stability of the environment is the key factor in determining whether tren.

Not sure how to do this case analysis please help me do it!1.Are t.pdf

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In each of the following situations, data are obtained by conducting a research study. Classify each Experimental or Correlational. Research Study A researcher is interested in whether listening to different types of music or no music while taking a test affects test scores. Students are randomly assigned to one of three groups: The first group takes a test without listening to an iPod, the second group takes the same test while listening to classical music on an iPod, and the third group takes the test while listening to rock music on an iPod. The researcher compares the test scores across the three groups. A psychologist is interested in gender and cognition. She collects data on a large sample of siblings, recording their gender, birth order, and IQ. A professor of ophthalmology is interested in developmental precursors of vision disorders. He collects data from a sample of teenagers on right-eye vision, left-eye vision, and whether the bedroom light was kept off or on as they slept during the night as babies. Solution 1) Experimental ( There is intervention- types of music) 2) correlational ( There is No intervention, only collection of data) 3) correlational ( There is No intervention, only collection of data).

In each of the following situations, data are obtained by conducting .pdf

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i need a summary book report on thw Iwo by richard wheeler Solution As part of my ongoing research on a historical novel I want to write set in the 1930s and 40s, I bought this book on the Battle of Iwo Jima. My father was there as a radioman and gunner on a landing craft, and I had known some basic information about the battle, but this book did a good job of filling in the gaps. Further, Wheeler does a thorough job of including the visceral details that add both incredible realism and admiration for those who experienced this battle. A wounded veteran of Iwo Jima himself, Wheeler did comprehensive interviewing as part of the background research for this book. He also interviewed Japanese survivors and got access to letters written by notable Japanese soldiers such as General Tadamichi Kuribayashi, the architect of the defenses on Iwo and commander of forces there. Having the Japanese perspective added greatly to the telling of the story. This is not fiction; this was a nonfiction retelling of the story. There was substantial detail in the recounting of many individual incidents. The only downside of the story was that it was encyclopedic in approach. Whether it was the chosen approach of the author or his writing style, the story never got personal. Perhaps if it had gotten too personal, the numerous anecdotes would have suffered somehow. Unfortunately, I found the writing stiff and formal, more like a textbook than narrative. The information and individual incidents were extensive, visceral and incredible. Wheeler writes in one place of a Marine who suffered injuries from five artillery shells, one after the other, but remarkable survived them, albeit with major injuries. He also goes into detail as to which units were involved in which assaults and who took the most damage, include Easy Company’s assault on Mount Surabachi and the famous hoisting of American colors on that mountain..

i need a summary book report on thw Iwoby richard wheelerSolut.pdf

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18 Alicia climbs into the passenger side of her boyfriend Bo\'s car. In an attempt to impress Alicia, Bo speeds away from the curb as Alicia\'s head presses against the headrest. What allows Alicia to sense this linear acceleration? A When thrust backward, the medulla sends signals to the cortex. B When thrust backward, the cerebellum sends signals to the cortex. C Hair cells in the cochlea bend with the forward motion. D Hair cells in the vestibular system bend with the forward motion. Solution 18. Option D. Hair cells in the vestibular system bend in the forward motion. Vestibular system (otolithic organs) makes us aware of the balance, acceleration. 23. Option C.think the apple and the potato are the same. Smell and taste receptors work together to give a sense of the taste of the food. 25. Option B. safe Infants are hard wired to know that sweet taste is deliciuos and nutritious and bitter means poison..

18 Alicia climbs into the passenger side of her boyfriend Bos car. .pdf

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