What are the cellular differences between fungi and protists? Solution 1.Fungi live in aerobic environment to survive, whereas protists live in an anaerobic environment. 2. protists are single-celled, however fungi are multi-celled. 3.The protista kingdom consists of members which are autotrophic and heterotrophic. The autotrophs are able to make their own food even as heterotrophs depend on others for food. Fungi can not be considered autotrophic or heterotrophic, although they extra closely relate to the heterotrophs. Members of the fungi are saprophytes I.e. consume dead or composing material..