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THE NERVOUS SYSTEM
OVERVIEW OF THE NERVOUS
SYSTEM
The nervous
system has two
major anatomical
subdivisions;
The central
nervous system
(CNS)
The peripheral
nervous system
(PNS)
SUBDIVISION OF THE NERVOUS
SYSTEM
CELLS OF THE NERVOUS SYSTEM
There are two cells of the nervous
system. These are;
Neuron
Neuroglia
The functional unit of the nervous
system is the nerve cell, or neuron
Neuroglia or glial are supportive cells in
the nervous system that aid the function
of neurons
NEURONS (Nerve Cells)
Neurons have three fundamental
physiological properties:
1. Excitability
2. Conductivity
3. Secretion
A typical neuron is divided into three
parts;
 Soma or cell body (perikaryon)
 Dendrites
 Axon
STRUCTURE OF A NEURON
CLASSIFICATION OF NEURONS
Neurons may be classified according
to structure or function.
Function
neuron
• Interneuron
(association)
• Motor neuron
Structure
• Sensory (afferent)• Unipolar neurons
• Bipolar neurons
• Multipolar
neurons
• Anaxonic neurons
FUNCTIONAL CLASSIFICATION
STRUCTURAL CLASSIFICATION
NEUROGLIA (Glia)
There are six types of supportive cells
Four occur in the CNS
 Oligodendrocytes
 Ependymal cells
 Microglia
 Astrocytes
Two occur in the PNS
 Schwann cells (Neurilemmocytes)
 Satellite cells
TYPES OF NEUROGLIA
SYNAPTIC TRANSMISSION
The meeting point between a neuron
and any other cell is called a synapse
The synapses b/t neurons and skeletal
muscle cells are referred to as
myoneural or neuromuscular
junction
Synapse can be;
Chemical synapse
Electrical synapse
ANATOMY OF A SYNAPSE
CENTRAL NERVOUS SYSTEM
The CNS consists of the brain
and spinal cord
CNS protected by a cranium
surrounding the brain
vertebral column surrounding
the spinal cord
The CNS is bathed in
cerebrospinal fluid
The CNS is composed of gray
and white matter
THE BRAIN
The brain is semi-spherical but soft delicate
complex organ.
It is the center for control and integration
An adult brain weighs near 1.5 kg (3-3.5lbs)
Averages about 1,600 g (3.5 lb) in men
1,450 g in women
Composed of an estimated 100 billion (1011)
neurons
Anatomically, the brain is divided into 3 region;
Forebrain
Midbrain
Hindbrain
DIVISIONS OF THE BRAIN
The brain is lined by membrane
called meninges.
The brain is conspicuously marked
by surface gyri (folds) and sulci
(grooves).
The human brain is composed of
neurons, glial cells and blood
vessels.
It also consists of four internal,
interconnected chambers called
ventricles.
SURFACE ANATOMY OF THE BRAIN
FOREBRAIN
 Forebrain consist of the following regions; Telecephalon
(cerebrum) and Diencephalon (Thalamus, hypothalamus,
epithalamus and pituitary gland)
 CEREBRUM
 The cerebrum is the largest part of the brain.
 It is divided into two hemispheres separated by the
longitudinal fissure.
 The hemispheres are prominently marked with gyri and
sulci.
 Portions of the two hemispheres are connected internally
by the corpus callosum
 Each cerebral hemisphere is subdivided by deep sulci, or
fissures, into the five lobes: Frontal, Parietal, Occipital,
Temporal and Insula
ANATOMY OF THE CEREBRUM
LOBES OF THE CEREBRUM
DIENCEPHALON
A major autonomic region of the brain that consists of vital
structures such as;
Thalamus, Hypothalamus , Epithalamus , Pituitary
gland
completely surrounded by the cerebral hemisphere of the
telencephalon.
These structures surround the third ventricle of the brain
The thalamus is a large ovoid mass of gray matter
The hypothalamus is a small portion of the diencephalon
inferior to the thalamus
The epithalamus is the dorsal portion of the diencephalon
that includes a thin roof over the third ventricle.
The pituitary gland, or hypophysis, is positioned on the
inferior aspect of the diencephalon
MIDBRAIN
The midbrain is a short section of the
brain stem between the diencephalon
and the pons
A short segment of the brainstem that
connects the hindbrain and forebrain
Within the midbrain is the cerebral
aqueduct (aqueduct of Sylvius)
It includes important centers for
vision, hearing, pain, and motor
control
ANATOMY OF THE MIDBRAIN
HINDBRAIN
The embryonic hindbrain differentiates into two
subdivisions the metencephalon and
myelencephalon
The metencephalon is the most superior portion
of the hindbrain.
The pons which measures about 2.5 cm long,
forms a broad anterior bulge in the brainstem
just rostral to the medulla.
It conducts signals up and down the brainstem
and between the brainstem and cerebellum
The cerebellum is the largest part of the
hindbrain and receives most of its input by way
of the pons.
Occupies the inferior and posterior aspect of
the cranial cavity
ANATOMY OF HINDBRAIN
MYELENCEPHALON
Myelencephalon
contain the
medulla oblongata
The medulla
oblongata is a
bulbous structure
about 3 cm (1In)
long
Externally, the
medulla resembles
the spinal cord
MENINGES OF THE
CENTRAL NERVOUS SYSTEM
The CNS is protected by
three connective tissue
membranes coverings
called meninges
From superficial to deep,
they are;
Dura mater,
Arachnoid mater,
Pia mater
CEREBROSPINAL FLUID &
VENTRICLES OF THE BRAIN
 ventricles
Two lateral ventricles
A third and fourth ventricles
The brain has four internal chamber called
The fourth ventricle is located in the brain
stem
The cerebral aqueduct (aqueduct of
Sylvius) passes through the midbrain to
link the third and fourth ventricles.
 CSF is a clear fluid that forms a protective
cushion around and within the CNS
VENTRICLES OF THE BRAIN
SPINAL CORD
It is an elongated cylindrical structure that is a
ropelike bundle of nervous tissue
In adults, it averages about 1.8 cm thick and 45
cm long
It begins as a continuation of the medulla
oblongata at the level of the foramen magnum
The spinal cord serves three principal functions:
Conduction, Locomotion and Reflexes
The cord gives rise to 31 pairs of spinal
nerves. the part supplied by each pair of spinal
nerves is called a segment.
The spinal cord is divided into cervical,
thoracic, lumbar, and sacral regions.
STRUCTURE OF THE SPINAL CORD
(Surface Anatomy)
CROSS-SECTIONAL ANATOMY
The spinal cord consists of two kinds of
nervous tissue called gray and white
matter.
Gray matter has a relatively dull color
because it contains little myelin.
It has butterfly- or H-shaped in cross
sections
It contains the somas, dendrites, and
proximal parts of the axons of neurons.
It is the site of synaptic contact between
neurons (information processing)
GRAY AND WHITE MATTER
White matter contains an abundance of myelinated
axons, which give it a bright, pearly white
appearance.
It is composed of bundles of axons called tracts or
fascicule
It carry signals from one part of the CNS to another.
The spinal cord has two tracts; Ascending and
descending tract
Ascending tracts carry sensory information up the
cord and descending tracts conduct motor
impulses down
TRACT OF THE SPINAL CORD
PERIPHERAL NERVOUS SYSTEM
The (PNS) is that portion of
the nervous system outside
the central nervous system
Sensory receptors within the
sensory organs, neurons,
nerve, ganglia, and plexuses
are all part of the PNS
The nerves of the PNS are
classified as;
 cranial nerves or spinal nerves,
GENERAL ANATOMY OF
NERVES AND GANGLIA
Anerve is a cordlike organ composed of
numerous nerve fibers (axons) bound together
by connective tissue.
Nerve fibers of the peripheral nervous system
are ensheathed in Schwann cells, which form a
neurilemma and often a myelin sheath around
the axon. Nerves has:
endoneurium, perineurium and epineurium
ANATOMY OF A NERVE
CRANIAL NERVES
Cranial nerves are nerves that emerge directly
from the brain and the brainstem.
There are 12 pairs of cranial nerves, numbered I
to XII
They relay information between the brain and
parts of the body.
Considers to be parts of both CNS and PNS
They are traditionally classified as sensory,
motor or mixed base on their functions.
CRANIAL NERVES
FUNCTIONS OF CRANIAL NERVES
SPINAL NERVES
There are 31 pairs of spinal nerves: 8 cervical
(C1–C8), 12 thoracic (T1–T12), 5 lumbar
(L1–L5), 5 sacral (S1–S5), and 1 coccygeal
(Co).
The first cervical nerve emerges between the
skull and atlas
The others emerge through intervertebral
foramina, including the anterior and posterior
foramina of the sacrum and the sacral hiatus.
AUTONOMIC NERVOUS SYSTEM (ANS)
ANS is motor nervous system that controls
glands, cardiac muscle, and smooth muscle
The primary target organs of the ANS are the
viscera of the thoracic and abdominal cavities
Its job is to regulate such fundamental states
and life processes as heart rate, blood
pressure, body temperature, respiratory
airflow, pupillary diameter, digestion,
energy metabolism, defecation, and
urination.
DIVISION OF THE ANS
The ANS has two subsystems
Sympathetic
parasympathetic divisions
Sympathetic (Thoracolumbar) Division
The sympathetic division is also called the
thoracolumbar division
It has relatively short preganglionic and
long postganglionic fibers
PARASYMPATHETIC DIVISION
The parasympathetic division is also
called the craniosacral
Somas of the preganglionic neurons are
located in the pons, medulla oblongata,
and segments S2 to S4 of the spinal cord
The parasympathetic division has long
preganglionic fibers reaching almost all
the way to the target cells
short postganglionic fibers that cover the
rest of the distance.

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Overview of the Nervous System

  • 2. OVERVIEW OF THE NERVOUS SYSTEM The nervous system has two major anatomical subdivisions; The central nervous system (CNS) The peripheral nervous system (PNS)
  • 3. SUBDIVISION OF THE NERVOUS SYSTEM
  • 4. CELLS OF THE NERVOUS SYSTEM There are two cells of the nervous system. These are; Neuron Neuroglia The functional unit of the nervous system is the nerve cell, or neuron Neuroglia or glial are supportive cells in the nervous system that aid the function of neurons
  • 5. NEURONS (Nerve Cells) Neurons have three fundamental physiological properties: 1. Excitability 2. Conductivity 3. Secretion A typical neuron is divided into three parts;  Soma or cell body (perikaryon)  Dendrites  Axon
  • 6. STRUCTURE OF A NEURON
  • 7. CLASSIFICATION OF NEURONS Neurons may be classified according to structure or function. Function neuron • Interneuron (association) • Motor neuron Structure • Sensory (afferent)• Unipolar neurons • Bipolar neurons • Multipolar neurons • Anaxonic neurons
  • 10. NEUROGLIA (Glia) There are six types of supportive cells Four occur in the CNS  Oligodendrocytes  Ependymal cells  Microglia  Astrocytes Two occur in the PNS  Schwann cells (Neurilemmocytes)  Satellite cells
  • 12. SYNAPTIC TRANSMISSION The meeting point between a neuron and any other cell is called a synapse The synapses b/t neurons and skeletal muscle cells are referred to as myoneural or neuromuscular junction Synapse can be; Chemical synapse Electrical synapse
  • 13. ANATOMY OF A SYNAPSE
  • 14. CENTRAL NERVOUS SYSTEM The CNS consists of the brain and spinal cord CNS protected by a cranium surrounding the brain vertebral column surrounding the spinal cord The CNS is bathed in cerebrospinal fluid The CNS is composed of gray and white matter
  • 15. THE BRAIN The brain is semi-spherical but soft delicate complex organ. It is the center for control and integration An adult brain weighs near 1.5 kg (3-3.5lbs) Averages about 1,600 g (3.5 lb) in men 1,450 g in women Composed of an estimated 100 billion (1011) neurons Anatomically, the brain is divided into 3 region; Forebrain Midbrain Hindbrain
  • 17.
  • 18. The brain is lined by membrane called meninges. The brain is conspicuously marked by surface gyri (folds) and sulci (grooves). The human brain is composed of neurons, glial cells and blood vessels. It also consists of four internal, interconnected chambers called ventricles.
  • 19. SURFACE ANATOMY OF THE BRAIN
  • 20. FOREBRAIN  Forebrain consist of the following regions; Telecephalon (cerebrum) and Diencephalon (Thalamus, hypothalamus, epithalamus and pituitary gland)  CEREBRUM  The cerebrum is the largest part of the brain.  It is divided into two hemispheres separated by the longitudinal fissure.  The hemispheres are prominently marked with gyri and sulci.  Portions of the two hemispheres are connected internally by the corpus callosum  Each cerebral hemisphere is subdivided by deep sulci, or fissures, into the five lobes: Frontal, Parietal, Occipital, Temporal and Insula
  • 21. ANATOMY OF THE CEREBRUM
  • 22. LOBES OF THE CEREBRUM
  • 23. DIENCEPHALON A major autonomic region of the brain that consists of vital structures such as; Thalamus, Hypothalamus , Epithalamus , Pituitary gland completely surrounded by the cerebral hemisphere of the telencephalon. These structures surround the third ventricle of the brain The thalamus is a large ovoid mass of gray matter The hypothalamus is a small portion of the diencephalon inferior to the thalamus The epithalamus is the dorsal portion of the diencephalon that includes a thin roof over the third ventricle. The pituitary gland, or hypophysis, is positioned on the inferior aspect of the diencephalon
  • 24. MIDBRAIN The midbrain is a short section of the brain stem between the diencephalon and the pons A short segment of the brainstem that connects the hindbrain and forebrain Within the midbrain is the cerebral aqueduct (aqueduct of Sylvius) It includes important centers for vision, hearing, pain, and motor control
  • 25. ANATOMY OF THE MIDBRAIN
  • 26. HINDBRAIN The embryonic hindbrain differentiates into two subdivisions the metencephalon and myelencephalon The metencephalon is the most superior portion of the hindbrain. The pons which measures about 2.5 cm long, forms a broad anterior bulge in the brainstem just rostral to the medulla. It conducts signals up and down the brainstem and between the brainstem and cerebellum The cerebellum is the largest part of the hindbrain and receives most of its input by way of the pons. Occupies the inferior and posterior aspect of the cranial cavity
  • 28. MYELENCEPHALON Myelencephalon contain the medulla oblongata The medulla oblongata is a bulbous structure about 3 cm (1In) long Externally, the medulla resembles the spinal cord
  • 29. MENINGES OF THE CENTRAL NERVOUS SYSTEM The CNS is protected by three connective tissue membranes coverings called meninges From superficial to deep, they are; Dura mater, Arachnoid mater, Pia mater
  • 30. CEREBROSPINAL FLUID & VENTRICLES OF THE BRAIN  ventricles Two lateral ventricles A third and fourth ventricles The brain has four internal chamber called The fourth ventricle is located in the brain stem The cerebral aqueduct (aqueduct of Sylvius) passes through the midbrain to link the third and fourth ventricles.  CSF is a clear fluid that forms a protective cushion around and within the CNS
  • 32. SPINAL CORD It is an elongated cylindrical structure that is a ropelike bundle of nervous tissue In adults, it averages about 1.8 cm thick and 45 cm long It begins as a continuation of the medulla oblongata at the level of the foramen magnum The spinal cord serves three principal functions: Conduction, Locomotion and Reflexes The cord gives rise to 31 pairs of spinal nerves. the part supplied by each pair of spinal nerves is called a segment. The spinal cord is divided into cervical, thoracic, lumbar, and sacral regions.
  • 33. STRUCTURE OF THE SPINAL CORD (Surface Anatomy)
  • 34. CROSS-SECTIONAL ANATOMY The spinal cord consists of two kinds of nervous tissue called gray and white matter. Gray matter has a relatively dull color because it contains little myelin. It has butterfly- or H-shaped in cross sections It contains the somas, dendrites, and proximal parts of the axons of neurons. It is the site of synaptic contact between neurons (information processing)
  • 35. GRAY AND WHITE MATTER
  • 36. White matter contains an abundance of myelinated axons, which give it a bright, pearly white appearance. It is composed of bundles of axons called tracts or fascicule It carry signals from one part of the CNS to another. The spinal cord has two tracts; Ascending and descending tract Ascending tracts carry sensory information up the cord and descending tracts conduct motor impulses down
  • 37. TRACT OF THE SPINAL CORD
  • 38. PERIPHERAL NERVOUS SYSTEM The (PNS) is that portion of the nervous system outside the central nervous system Sensory receptors within the sensory organs, neurons, nerve, ganglia, and plexuses are all part of the PNS The nerves of the PNS are classified as;  cranial nerves or spinal nerves,
  • 39. GENERAL ANATOMY OF NERVES AND GANGLIA Anerve is a cordlike organ composed of numerous nerve fibers (axons) bound together by connective tissue. Nerve fibers of the peripheral nervous system are ensheathed in Schwann cells, which form a neurilemma and often a myelin sheath around the axon. Nerves has: endoneurium, perineurium and epineurium
  • 40. ANATOMY OF A NERVE
  • 41. CRANIAL NERVES Cranial nerves are nerves that emerge directly from the brain and the brainstem. There are 12 pairs of cranial nerves, numbered I to XII They relay information between the brain and parts of the body. Considers to be parts of both CNS and PNS They are traditionally classified as sensory, motor or mixed base on their functions.
  • 44. SPINAL NERVES There are 31 pairs of spinal nerves: 8 cervical (C1–C8), 12 thoracic (T1–T12), 5 lumbar (L1–L5), 5 sacral (S1–S5), and 1 coccygeal (Co). The first cervical nerve emerges between the skull and atlas The others emerge through intervertebral foramina, including the anterior and posterior foramina of the sacrum and the sacral hiatus.
  • 45.
  • 46. AUTONOMIC NERVOUS SYSTEM (ANS) ANS is motor nervous system that controls glands, cardiac muscle, and smooth muscle The primary target organs of the ANS are the viscera of the thoracic and abdominal cavities Its job is to regulate such fundamental states and life processes as heart rate, blood pressure, body temperature, respiratory airflow, pupillary diameter, digestion, energy metabolism, defecation, and urination.
  • 47. DIVISION OF THE ANS The ANS has two subsystems Sympathetic parasympathetic divisions Sympathetic (Thoracolumbar) Division The sympathetic division is also called the thoracolumbar division It has relatively short preganglionic and long postganglionic fibers
  • 48. PARASYMPATHETIC DIVISION The parasympathetic division is also called the craniosacral Somas of the preganglionic neurons are located in the pons, medulla oblongata, and segments S2 to S4 of the spinal cord The parasympathetic division has long preganglionic fibers reaching almost all the way to the target cells short postganglionic fibers that cover the rest of the distance.