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SPINAL CORD
By: Maryam Bahrami
 The spinal cord is the extension of
the CNS below the level of the
skull. It is an elongated structure
that is located in the vertebral
canal.
 It stretches from upper border of
the foramen Magnum to the
intervertebral disc between the
first and second lumbar vertebrae.
spinal cord
 At birth, this end is at the level of
the third lumbar vertebra.
 With increasing age, the vertebral
column and dura lengthen more
rapidly than the neural tube, and
the terminal end of the spinal
cord gradually shifts to a higher
level.
 The spinal cord has two
enlargement:
 Cervical enlargement (C4-T1)
 Lumbar enlargement (L2-S3)
 Conus medularis
Features of the outer surface
of the spinal cord:
 Anterior Median Fissure
 Posterior Median Fissure
 Anterolateral sulci
 Posterolateral sulci
 Linea splendens
 31 pairs of spinal nerves:
 8 cervical
 12 thoracic
 5 lumbar
 5 sacral
 1 coccygeal
 Dorsal root – sensory fibres
 Ventral root – motor fibres
 Dorsal and ventral roots join at
intervertebral foramen to form the spinal
nerve
 Spinal segment
Cauda equina
Meninges of spinal cord
Spinal cord surrounded by 3 layers of meniges:
 dura mater
 arachnoid
 pia mater
 Filum terminalis
 Lumbar cicterna
 Coccygeal ligament
 Epidural space
 Subdural space
 Subarachnoid space
Lumbar Puncture
Denticulate ligament
Internal organization Of The Spinal Cord
Each spinal segment consists of central gray and peripheral white matters.
Gray Matter
 H-shaped
 anterior horns
 poster horns
 lateral horns
 Anterior horns
 Head
 Base
 Poster horns
 Head
 Base
 neck
White Matter
It is divided into 3 large funiculus on each side:
 Anterior funiculus :
lies between the ant. median fissure & the Anterolateral sulci.
 Posterior funiculus :
lies between the post median septum & the posterolateral sulci.
 Lateral funiculus :
lies between the posterolateral sulci and the Anterolateral sulci.
 Fasciculus gracilis
 Fasciculus cuneatus
spinal cord commissures:
 Gray commissure
 White commissure
Gray matter and nuclei
Nuclei of the anterior horn
(motor)
are grouped into 3 groups of
motor nuclei:
1. Medial group:
o found in all segments of the spinal
cord (Except L5-S1)
o All of thorasic segments and L1-
L3/4:
• Dorsomedial
• Ventromedial
o C1
• Dorsomedial
o All of cervical segments and S2-Co
• Ventromedial
o innervating the skeletal muscles of
the neck & trunk.
2. Central group:
present in some cervical &
lumbosacral segments
• Phrenic nucleus (C3-C5 segments)
• Accessory nucleus (C1-C5/6
segments)
• Lumbosacral nucleus ( L2-S1
segments)
3. Lateral group:
o present in the cervical &
lumbosacral segments
• Ventrolateral nuclei
• Dorsolateral nuclei
• Retrodorsolateral nuclei
o innervating the skeletal muscles of
the limbs.
Nuclei of the posterior horn
1. Posteromarginal nucleus
2. Substatia gelatinosa
3. Nucleus Proprius
4. Clark’s/ dorsal nucleus
o situated at the base of the
posterior gray column in the
thoracic & upper lumbar region
only(C8-L3)
o The cells are associated with
proprioceptive impulses
o Its axons ascend in the lat.
column of the same side
forming the posterior
spinocerebellar tract
5. nucleus centrobasalis
Lower cervical segments and
lumbosacral segments
6. Intermediate cell column
(visceral afferent nucleus)
o situated at T1-L2 and S2-S4
o The cells are associated
with autonomy system
probably
III. Nuclei of the Intermediate gray
Present in the segment from T1 to L2/3
and S2-S4
o T1 to L2/3 segment
• Intermediomedial
• Intermediolateral (lateral horn)
o S2-S4
• Sacral parasampathetic gray column
White Matter
 Anterior funiculus
 Posterior funiculus
 Lateral funiculus
 Fasciculus gracilis
 Fasciculus cuneatus
 Spinal tracts
PATHWAYS IN WHITE MATTER
the white matter contains 5 types of nerve fibers:
 Afferent fibers
 Long ascending fibers
 Long descending fibers
 Intersegmental & Intrasegmental fibers(propria fiber)
 Efferent fibers
Formation of the fasciculus gracilis and cuneatus
 Septomarginal tract
 Comma tract
1.Lateral Spinothalamic Tract
• Transmit impulses from pain &
temprature receptor.
2.Anterior Spinothalamic Tract
 Transmit impulses from light
touch & pressure receptor.
4. Anterior Spinocerebellar Tract
5. Posterior Spinocerebellar Tract
6.Cuneo cerebellar tract
7. Spinotectal tract
spinovisual reflexes
8. Spino-olivary tract
indirect pathway to cerebellum
9. Spinoreticular tract
info from muscles, joints & skin to reticular
formation
10. Spinovestibular tract
Descending Fiber Systems
Pyramidal tract:
Upper Motor Neurons
 Are the nerve fibers that descend in the white matter from
different supraspinal nerve centers
 provide numerous separate pathways that can influence motor
activity.
Lower Motor Neurons
 Are the motor neurons situated in the anterior gray columns of
the spinal cord sending axons to innervate skeletal muscle
 constitute the final common pathway to the muscles.
1. Corticospinal Tract
2. Rubrospinal tract:
 Arises from the red nucleus &
crosses to the opposite side
 Descends in the lat. column of
the spinal cord
Function:
 facilitates the activity of flexor
muscles
3. Tectospinal Tract:
 Arises from the sup. colliculus of
midbrain
 Crosses to the opposite side
 Descends in the ant. column of
the spinal cord
Function
concerned with reflex postural
movements in response to visual
stimuli
4. Vestibulospinal Tract
 Arises from the lat-vestibular nucleus in
the pons
 majority of its fibres are uncrossed
 Descends in the ant. column of the
spinal cord
Function:
is concerned with the postural activity
associated with balance.
5. Reticulospinal Tract
6. Olivospinal Tract
7. Medial longitudinal fasciculus(MLF)
Blood Vessels of the Spinal Cord: Arteries
Blood Vessels of the Spinal Cord: Veins
THANKS

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Spinal cord

  • 2.  The spinal cord is the extension of the CNS below the level of the skull. It is an elongated structure that is located in the vertebral canal.  It stretches from upper border of the foramen Magnum to the intervertebral disc between the first and second lumbar vertebrae. spinal cord
  • 3.  At birth, this end is at the level of the third lumbar vertebra.  With increasing age, the vertebral column and dura lengthen more rapidly than the neural tube, and the terminal end of the spinal cord gradually shifts to a higher level.
  • 4.  The spinal cord has two enlargement:  Cervical enlargement (C4-T1)  Lumbar enlargement (L2-S3)  Conus medularis
  • 5. Features of the outer surface of the spinal cord:  Anterior Median Fissure  Posterior Median Fissure  Anterolateral sulci  Posterolateral sulci  Linea splendens
  • 6.  31 pairs of spinal nerves:  8 cervical  12 thoracic  5 lumbar  5 sacral  1 coccygeal
  • 7.  Dorsal root – sensory fibres  Ventral root – motor fibres  Dorsal and ventral roots join at intervertebral foramen to form the spinal nerve  Spinal segment
  • 8.
  • 10. Meninges of spinal cord Spinal cord surrounded by 3 layers of meniges:  dura mater  arachnoid  pia mater
  • 11.  Filum terminalis  Lumbar cicterna  Coccygeal ligament
  • 12.  Epidural space  Subdural space  Subarachnoid space
  • 15. Internal organization Of The Spinal Cord Each spinal segment consists of central gray and peripheral white matters. Gray Matter  H-shaped  anterior horns  poster horns  lateral horns  Anterior horns  Head  Base  Poster horns  Head  Base  neck
  • 16.
  • 17. White Matter It is divided into 3 large funiculus on each side:  Anterior funiculus : lies between the ant. median fissure & the Anterolateral sulci.  Posterior funiculus : lies between the post median septum & the posterolateral sulci.  Lateral funiculus : lies between the posterolateral sulci and the Anterolateral sulci.  Fasciculus gracilis  Fasciculus cuneatus
  • 18. spinal cord commissures:  Gray commissure  White commissure
  • 19. Gray matter and nuclei
  • 20. Nuclei of the anterior horn (motor) are grouped into 3 groups of motor nuclei: 1. Medial group: o found in all segments of the spinal cord (Except L5-S1) o All of thorasic segments and L1- L3/4: • Dorsomedial • Ventromedial o C1 • Dorsomedial o All of cervical segments and S2-Co • Ventromedial o innervating the skeletal muscles of the neck & trunk.
  • 21. 2. Central group: present in some cervical & lumbosacral segments • Phrenic nucleus (C3-C5 segments) • Accessory nucleus (C1-C5/6 segments) • Lumbosacral nucleus ( L2-S1 segments) 3. Lateral group: o present in the cervical & lumbosacral segments • Ventrolateral nuclei • Dorsolateral nuclei • Retrodorsolateral nuclei o innervating the skeletal muscles of the limbs.
  • 22. Nuclei of the posterior horn 1. Posteromarginal nucleus 2. Substatia gelatinosa 3. Nucleus Proprius
  • 23. 4. Clark’s/ dorsal nucleus o situated at the base of the posterior gray column in the thoracic & upper lumbar region only(C8-L3) o The cells are associated with proprioceptive impulses o Its axons ascend in the lat. column of the same side forming the posterior spinocerebellar tract 5. nucleus centrobasalis Lower cervical segments and lumbosacral segments
  • 24. 6. Intermediate cell column (visceral afferent nucleus) o situated at T1-L2 and S2-S4 o The cells are associated with autonomy system probably
  • 25. III. Nuclei of the Intermediate gray Present in the segment from T1 to L2/3 and S2-S4 o T1 to L2/3 segment • Intermediomedial • Intermediolateral (lateral horn) o S2-S4 • Sacral parasampathetic gray column
  • 26. White Matter  Anterior funiculus  Posterior funiculus  Lateral funiculus  Fasciculus gracilis  Fasciculus cuneatus
  • 28. PATHWAYS IN WHITE MATTER the white matter contains 5 types of nerve fibers:  Afferent fibers  Long ascending fibers  Long descending fibers  Intersegmental & Intrasegmental fibers(propria fiber)  Efferent fibers
  • 29. Formation of the fasciculus gracilis and cuneatus
  • 30.
  • 32. 1.Lateral Spinothalamic Tract • Transmit impulses from pain & temprature receptor.
  • 33. 2.Anterior Spinothalamic Tract  Transmit impulses from light touch & pressure receptor.
  • 34. 4. Anterior Spinocerebellar Tract 5. Posterior Spinocerebellar Tract 6.Cuneo cerebellar tract
  • 36. 8. Spino-olivary tract indirect pathway to cerebellum
  • 37. 9. Spinoreticular tract info from muscles, joints & skin to reticular formation 10. Spinovestibular tract
  • 38. Descending Fiber Systems Pyramidal tract: Upper Motor Neurons  Are the nerve fibers that descend in the white matter from different supraspinal nerve centers  provide numerous separate pathways that can influence motor activity. Lower Motor Neurons  Are the motor neurons situated in the anterior gray columns of the spinal cord sending axons to innervate skeletal muscle  constitute the final common pathway to the muscles.
  • 40. 2. Rubrospinal tract:  Arises from the red nucleus & crosses to the opposite side  Descends in the lat. column of the spinal cord Function:  facilitates the activity of flexor muscles
  • 41. 3. Tectospinal Tract:  Arises from the sup. colliculus of midbrain  Crosses to the opposite side  Descends in the ant. column of the spinal cord Function concerned with reflex postural movements in response to visual stimuli
  • 42. 4. Vestibulospinal Tract  Arises from the lat-vestibular nucleus in the pons  majority of its fibres are uncrossed  Descends in the ant. column of the spinal cord Function: is concerned with the postural activity associated with balance.
  • 44. 6. Olivospinal Tract 7. Medial longitudinal fasciculus(MLF)
  • 45. Blood Vessels of the Spinal Cord: Arteries
  • 46.
  • 47. Blood Vessels of the Spinal Cord: Veins