17) Which of the following is NOT a feature of insulin? 1) glucose reducing hormone 2) produced by pancreatic beta cells 3) co dominant expression 4) polymorphism 5) polypeptides 14. Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis. After its being phagocytosed within macrophages, Mycobacterium tuberculosis can survive within the phagosomes. In the case of Mycobacteria infection, which of the following is CORRECT? A. Effector CD4 Th2 cells are required in the clearance of Mtb B. Nave CD4 T cells are activated by MHC I-presenting C. If the bacteria escape from the phagosome into cytosol, CTLs will cooperate with CD4 effector T cells to clear the infection D. Mycobacteria-induced CD28 expression on dendritic cells is critical for nave T cell activation. E. When arriving at lungs, effector CD4T cells activate Mtb-infected macrophages through B7-CD28 interaction. 15. Which is INCORRECT in the biochemical pathways in naive T cell activation induced by antigen recognition? A. activation of NF-AT, NF-B and AP-1 B. activation of biochemical pathways drives the expression of IL-2 C. phosphorylation of ITAMs on CD3 and zeta chain D. induces the expression of IL-4 E. blockade of TCR-induced biochemical signaling pathways can inhibit Tcell medicated organ rejection after transplantation 16. Which is NOT involved in infiltration of effector T cells to site of infection? A. expression of E- and P-selectin ligand B. antigen recognition C. rolling and adhesion of T cells on endothelium D. affinity change in the binding between LFA-1 and ICAM-1 E. expression of chemokine receptors on T cells.