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Cyclic Changes in the 
Female Genital System 
۰۶:۴۴ By Dr:Abdulwdood(Afghanmal)
Ovulation 
In every 28 days 
Primordial follicle --- Graafian follicle 
(primordial follical, primary follical, secondary follical, mature follical) 
Starting from 11 – 16 years of life 
Ending at 45 – 50 years (menopause) 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
• Two cycles take place simultaneously in 
the female genital system: 
1: Ovarian cycle: 
2: Menstruation or uterine cycle 
1: Ovarian cycle 
A:Pre-ovulatory Phase 
 Secretion of FSH from hipophysis 
 Development and growth of ovarian follicles 
 Proliferation of the endometrium 
 Secretion of estrogen hormone 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
B: Ovulation Phase 
 Takes place on the 14th (+/-1) day of ovulation cycle 
 Doesn’t take place during pregnancy 
 Rare in lactating women 
 Mechanism: 
 Under the influence of Luteatropin hormone 
 Increased fluid pressure in the follicle 
 Influence of collagenase and plasmin enzymes 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
C: Post ovulatory phase 
 Formation of corpus luteum 
 Temporary endocrine gland 
 Secrets progesterone 
 Control by LH 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
4. Involution or Regression phase 
 Corpus luteum gets atrophy and turns to corpus albicans 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
2: Menstruation or Uterine Cycle 
Premenstrauation or Secretory Phase 
 12 days 
 Endometrial thickness reaches to the maximum 
 Secretion of uterine glands 
 Glycogen 
 Mucin 
 Uterine is ready for the implantation of fertilized ovum 
 Also called luteal phase 
 If the ovum has not fertilized 12-14 day and no progesterone 
 If the ovum has fertilized 3-4 month( plasenta formation) 
۰۶:۴۴ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
A: Menstrual phase 
 3-5 days 
 50 – 60cc blood 
 No coagulation due to the presence of proteolytic enzymes 
 Thickness of endometrium remains 1/10 of the normal 
۰۶:۴۴ Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
Post menstruation or Proliferation Phase 
 10 days 
 Endometrium repairs under the influence of estrogen 
hormone 
 Also called follicular phase 
۰۶:۴۴ Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
۰۶:۴۴ Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu
TThhee eenndd 
ببرريياالليي 
ااووسسئئ 
۱۳۹۳/۶/ سه شنبه: ۱۹ 
Presentation of Embryology by 
Dr:Ab.wadood(Afghanmal) 
Mu

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Cyclic changes

  • 1. Cyclic Changes in the Female Genital System ۰۶:۴۴ By Dr:Abdulwdood(Afghanmal)
  • 2. Ovulation In every 28 days Primordial follicle --- Graafian follicle (primordial follical, primary follical, secondary follical, mature follical) Starting from 11 – 16 years of life Ending at 45 – 50 years (menopause) ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 3. • Two cycles take place simultaneously in the female genital system: 1: Ovarian cycle: 2: Menstruation or uterine cycle 1: Ovarian cycle A:Pre-ovulatory Phase  Secretion of FSH from hipophysis  Development and growth of ovarian follicles  Proliferation of the endometrium  Secretion of estrogen hormone ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 4. B: Ovulation Phase  Takes place on the 14th (+/-1) day of ovulation cycle  Doesn’t take place during pregnancy  Rare in lactating women  Mechanism:  Under the influence of Luteatropin hormone  Increased fluid pressure in the follicle  Influence of collagenase and plasmin enzymes ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 5. C: Post ovulatory phase  Formation of corpus luteum  Temporary endocrine gland  Secrets progesterone  Control by LH ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 6. ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 7. 4. Involution or Regression phase  Corpus luteum gets atrophy and turns to corpus albicans ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 8. ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 9. 2: Menstruation or Uterine Cycle Premenstrauation or Secretory Phase  12 days  Endometrial thickness reaches to the maximum  Secretion of uterine glands  Glycogen  Mucin  Uterine is ready for the implantation of fertilized ovum  Also called luteal phase  If the ovum has not fertilized 12-14 day and no progesterone  If the ovum has fertilized 3-4 month( plasenta formation) ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 10. A: Menstrual phase  3-5 days  50 – 60cc blood  No coagulation due to the presence of proteolytic enzymes  Thickness of endometrium remains 1/10 of the normal ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 11. Post menstruation or Proliferation Phase  10 days  Endometrium repairs under the influence of estrogen hormone  Also called follicular phase ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 12. ۰۶:۴۴ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu
  • 13.
  • 14. TThhee eenndd ببرريياالليي ااووسسئئ ۱۳۹۳/۶/ سه شنبه: ۱۹ Presentation of Embryology by Dr:Ab.wadood(Afghanmal) Mu