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IMMUNE SYSTEM
ZAMOKUHLE MYENI
LIFE SCIENCES
GRADE 11
INTRODUCTION TO IMMUNITY
• Immune system  system of
biological structures + processes within
organism
• protects against disease.
• Organism function properly  immune system
 detect wide variety of agents
• (viruses, parasitic worms)
• distinguish them from own healthy tissue.
INNATE IMMUNE SYSTEMS
Cells + proteins  always present & ready to mobilize
 fight microbes at site of infection.
Main components of innate immune system:
1) physical epithelial barriers,
2) phagocytic leukocytes (WBC)
3) dendritic cells,
4) a special type of lymphocyte called a natural killer (NK) cell,
5) circulating plasma proteins.
 If pathogens successfully evade innate response  vertebrates
possess second layer of protection
acquired immune system
activated by innate response
 Now immune system adapts its response during infection 
improve its recognition of pathogen.
 Improved response  retained after pathogen eliminated
 immunological memory
 allows acquired immune system to act faster and stronger attacks
each time this pathogen is encountered.
Differences in the components of the
immune system
BARRIER DEFENSE SYSTEM
Includes:
 the skin
Mucus membranes of digestive-,
respiratory- urinary and reproductive
tract
oBody secretions: mucus, saliva
(lysozymes), tears, oil gland secretions,
acid in stomach, sweat.
Different types of phagocytic cells
Neutrophils  engulf and destroy microbes
Macrophages part of the lymphatic system
and are found throughout the body
Eosinophils  discharge destructive enzymes
Dendritic cells  stimulate development of
acquired immunity
PHAGOCYTE ENGULFING A BACTGERIUM
CELL
IMMUNE
SYSTEM
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Immune system slides

  • 2. INTRODUCTION TO IMMUNITY • Immune system  system of biological structures + processes within organism • protects against disease. • Organism function properly  immune system  detect wide variety of agents • (viruses, parasitic worms) • distinguish them from own healthy tissue.
  • 3. INNATE IMMUNE SYSTEMS Cells + proteins  always present & ready to mobilize  fight microbes at site of infection. Main components of innate immune system: 1) physical epithelial barriers, 2) phagocytic leukocytes (WBC) 3) dendritic cells, 4) a special type of lymphocyte called a natural killer (NK) cell, 5) circulating plasma proteins.
  • 4.  If pathogens successfully evade innate response  vertebrates possess second layer of protection acquired immune system activated by innate response  Now immune system adapts its response during infection  improve its recognition of pathogen.  Improved response  retained after pathogen eliminated  immunological memory  allows acquired immune system to act faster and stronger attacks each time this pathogen is encountered.
  • 5. Differences in the components of the immune system
  • 6. BARRIER DEFENSE SYSTEM Includes:  the skin Mucus membranes of digestive-, respiratory- urinary and reproductive tract oBody secretions: mucus, saliva (lysozymes), tears, oil gland secretions, acid in stomach, sweat.
  • 7. Different types of phagocytic cells Neutrophils  engulf and destroy microbes Macrophages part of the lymphatic system and are found throughout the body Eosinophils  discharge destructive enzymes Dendritic cells  stimulate development of acquired immunity
  • 8. PHAGOCYTE ENGULFING A BACTGERIUM CELL