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TERESITA M. PERUCHO
M
aster Teacher I- science
Mitosis &
Meiosis
 Compare mitosis and meiosis, and their
role in the cell-division cycle
S8LT-IV
d-16
 Explain the significance of meiosis in
maintaining the chromosome number
S8LT-IV
e-17
competency
OBJECTIVES
1. D
efine mitosis &meiosis
2. D
escribe the changes that occur
in each stage of mitosis &meiosis
CELL CYCLE
M
IT
O
SIS &
M
EIO
SIS
Guide
questions
Guide questions
What is
mitosis&
meiosis
Identify the stages of
mitosis ( in order ) ?
What are the four
important events that
happen during the cell
division?
What is mitosis& meiosis
M
itosis – cell division that happens in body
cells
M
eiosis – cell division that produces haploid sex
cells such as eggs and sperm cells
Interphase (g1 , s , g2 ) , prophase , metaphase
,anaphase , telophase and cytokinesis
Identify the stages of mitosis ( in order ) ?
1. Cell growth
2. Chromosome replacement
3. Chromosome segregation
4. Cell division
W
hat are the four important events that
happen during the cell division?
cELL
- (from Latincella , meaning "small
room") is the basic structural, functional,
and biological unit of all known organisms.
Cells are the smallest units of life, and
hence are often referred to as the "building
blocks of life".
CYTOLOGY
– study of cell.
The cell cycle, or cell- division cycle, is the series of
events that take place in a cell that cause it to divide
into two daughter cells.
The cell cycle is a four- stage processin which the
cell increases in size (gap 1, or G1, stage), copies its
DNA (synthesis, or S, stage), prepares to divide (gap 2
or G2, stage), and divides (mitosis, or M, stage). The
stages G1, S, and G2 make up interphase, which
accounts for the span between cell divisions.
CELL CYCLE
INTERPHASE
INTERPHASE
INTERPHASE
MITOSIS
Mitosis – cell division that happens in
body cells
CHROMOSOMES
 Chromosomes now called
chromatids
because they doubled to form short thick
rods which pair up and line up in the
center of the nucleus.
 A centromere connects the two halves of
the doubled chromatids.
 Spindle fibers begin to form.
Spindle fiber
– a fibrous structure from the
cytoplasm which forms to the centriole.
 Centrioles move to opposite sides of the
cell.
 The nuclear membrane breaks down.
PROPHAS
METAPHASE
 Centromeres of the chromatid
pairs line up in the middle of
the cell.
 Metaphase plate
- location
where the centromeres line up
in the center of the cell.
 By the end of metaphase each
chromatid has attached to
spindle fibers.
ANAPHASE
 The spindle fibers pull the
chromatids apart.
 This separates each one
from its duplicate. These
move to opposite sides of
the cell.
 Now there are two
identical sets of
chromosomes.
TELOPHASE
 When the chromosomes
reach opposite sides of the
cell the spindle fibers break
up.
 The nuclear membrane begins
to reform.
 A furrow begins to develop
between the two sets of
chromosomes.
CYTOKINESIS
The two identical cells completely divide and the cell
membrane is completely formed.It is the division of the
cytoplasm
Meiosis– cell division that
produces haploid sex cells such
as eggs and sperm cells
 D
iploid (2n) - Acell with two of each
kind of chromosome.
 O
ne chromosome from each parent.
If two body cells were to combine
nuclei, the number of chromosomes
would double.
 In order for sexual reproduction to
occur, each cell involved must
reduce its chromosome number by
half.
 Haploid (n)- Acell with one of each
kind of chromosome.
HAPLOID CELLS
Homologous Chromosomes
MEIOSIS
STAGES OF MEIOSIS
PROPHASE 1
Tetrads are so tight that non
-
sister chromatids from the
homologous pair actually
exchange genetic material.
Crossing over
- The exchange
of genetic material by non
-
sister chromatids during late
prophase I of meiosis.
Results in a new combination
of alleles
METAPHASE 1
 Homologous chromosomes line
up together in pairs.
 * In mitosis homologous
chromosomes line up in the
middle independently of each
other.
ANAPHASE 1
 Spindle fibers attach to the
centromeres of each pair.
 Homologous chromosomes
separate and move to
opposite ends of the cell.
 Centromeres DO NOT split like
they do in mitosis
 Now each cell will get one
chromosome from each
homologous pair.
TELOPHASE 1
 Spindle fibers break down
 Chromosomes uncoil
 Cytoplasm divides
 Another cell division is needed
because the number of
chromosomes has not been
reduced
 After telophase I there maybe a
short interphase, but not always.
It is important to note that if a cell
does have a second interphase,
there is No replication of
chromosomes
.
MEIOSIS 1
MEIOSIS 2
 Is basically just like mitosis, but
remember the chromosomes did
not duplicate in interphase II.
 Prophase II
Chromosomes begin to line up in
the middle of the cell.
Spindle fibers begin to form
 M
etaphase II
Chromosomes line up on the
metaphase plate
MEIOSIS 1
 Anaphase II
Centromeres split
Sister chromatids separate and
move to opposite sides of the cell
 T
elophase II
Nuclei reform
Spindle fibers disappear
Cytoplasm divides into two.
T
he number of chromosomes in
each daughter cell has now been
reduced by half.
MEIOSIS 2
MITOSIS
(ASEXUAL )
MEIOSIS
(SEXUAL)
Number of daughter cells produced
Function
Chromosome number
Pairing of homologous chromosomes take
place. (Yes/No)
The daughter cells produced are always
identical in terms of genetic material.
(Yes/No)
creates
ASSIGNMENT
Complete the table.
MITOSIS
(ASEXUAL )
MEIOSIS
(SEXUAL)
Number of daughter cells produced 2 4
Function Cellular reproduction
( asexual) ; for growth &
repair of the body.
Sexual reproduction
Chromosome number diploid haploid
Pairing of homologous chromosomes take
place. (Yes/No)
NO YES
The daughter cells produced are always
identical in terms of genetic material.
(Yes/No)
YES NO
creates Somatic cells ( body cells) Sex cells ( gametes)
Complete the table.
Thank you

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Mitosis & meiosis

  • 2. TERESITA M. PERUCHO M aster Teacher I- science Mitosis & Meiosis
  • 3.  Compare mitosis and meiosis, and their role in the cell-division cycle S8LT-IV d-16  Explain the significance of meiosis in maintaining the chromosome number S8LT-IV e-17 competency
  • 4. OBJECTIVES 1. D efine mitosis &meiosis 2. D escribe the changes that occur in each stage of mitosis &meiosis
  • 5.
  • 8. Guide questions What is mitosis& meiosis Identify the stages of mitosis ( in order ) ? What are the four important events that happen during the cell division?
  • 9. What is mitosis& meiosis M itosis – cell division that happens in body cells M eiosis – cell division that produces haploid sex cells such as eggs and sperm cells
  • 10. Interphase (g1 , s , g2 ) , prophase , metaphase ,anaphase , telophase and cytokinesis Identify the stages of mitosis ( in order ) ?
  • 11. 1. Cell growth 2. Chromosome replacement 3. Chromosome segregation 4. Cell division W hat are the four important events that happen during the cell division?
  • 12. cELL - (from Latincella , meaning "small room") is the basic structural, functional, and biological unit of all known organisms. Cells are the smallest units of life, and hence are often referred to as the "building blocks of life". CYTOLOGY – study of cell.
  • 13. The cell cycle, or cell- division cycle, is the series of events that take place in a cell that cause it to divide into two daughter cells. The cell cycle is a four- stage processin which the cell increases in size (gap 1, or G1, stage), copies its DNA (synthesis, or S, stage), prepares to divide (gap 2 or G2, stage), and divides (mitosis, or M, stage). The stages G1, S, and G2 make up interphase, which accounts for the span between cell divisions.
  • 18.
  • 19. MITOSIS Mitosis – cell division that happens in body cells
  • 21.  Chromosomes now called chromatids because they doubled to form short thick rods which pair up and line up in the center of the nucleus.  A centromere connects the two halves of the doubled chromatids.  Spindle fibers begin to form. Spindle fiber – a fibrous structure from the cytoplasm which forms to the centriole.  Centrioles move to opposite sides of the cell.  The nuclear membrane breaks down. PROPHAS
  • 22. METAPHASE  Centromeres of the chromatid pairs line up in the middle of the cell.  Metaphase plate - location where the centromeres line up in the center of the cell.  By the end of metaphase each chromatid has attached to spindle fibers.
  • 23. ANAPHASE  The spindle fibers pull the chromatids apart.  This separates each one from its duplicate. These move to opposite sides of the cell.  Now there are two identical sets of chromosomes.
  • 24. TELOPHASE  When the chromosomes reach opposite sides of the cell the spindle fibers break up.  The nuclear membrane begins to reform.  A furrow begins to develop between the two sets of chromosomes.
  • 25. CYTOKINESIS The two identical cells completely divide and the cell membrane is completely formed.It is the division of the cytoplasm
  • 26.
  • 27. Meiosis– cell division that produces haploid sex cells such as eggs and sperm cells  D iploid (2n) - Acell with two of each kind of chromosome.  O ne chromosome from each parent. If two body cells were to combine nuclei, the number of chromosomes would double.  In order for sexual reproduction to occur, each cell involved must reduce its chromosome number by half.  Haploid (n)- Acell with one of each kind of chromosome.
  • 32. PROPHASE 1 Tetrads are so tight that non - sister chromatids from the homologous pair actually exchange genetic material. Crossing over - The exchange of genetic material by non - sister chromatids during late prophase I of meiosis. Results in a new combination of alleles
  • 33. METAPHASE 1  Homologous chromosomes line up together in pairs.  * In mitosis homologous chromosomes line up in the middle independently of each other.
  • 34. ANAPHASE 1  Spindle fibers attach to the centromeres of each pair.  Homologous chromosomes separate and move to opposite ends of the cell.  Centromeres DO NOT split like they do in mitosis  Now each cell will get one chromosome from each homologous pair.
  • 35. TELOPHASE 1  Spindle fibers break down  Chromosomes uncoil  Cytoplasm divides  Another cell division is needed because the number of chromosomes has not been reduced  After telophase I there maybe a short interphase, but not always. It is important to note that if a cell does have a second interphase, there is No replication of chromosomes .
  • 37. MEIOSIS 2  Is basically just like mitosis, but remember the chromosomes did not duplicate in interphase II.  Prophase II Chromosomes begin to line up in the middle of the cell. Spindle fibers begin to form  M etaphase II Chromosomes line up on the metaphase plate
  • 38. MEIOSIS 1  Anaphase II Centromeres split Sister chromatids separate and move to opposite sides of the cell  T elophase II Nuclei reform Spindle fibers disappear Cytoplasm divides into two. T he number of chromosomes in each daughter cell has now been reduced by half.
  • 40.
  • 41.
  • 42. MITOSIS (ASEXUAL ) MEIOSIS (SEXUAL) Number of daughter cells produced Function Chromosome number Pairing of homologous chromosomes take place. (Yes/No) The daughter cells produced are always identical in terms of genetic material. (Yes/No) creates ASSIGNMENT Complete the table.
  • 43. MITOSIS (ASEXUAL ) MEIOSIS (SEXUAL) Number of daughter cells produced 2 4 Function Cellular reproduction ( asexual) ; for growth & repair of the body. Sexual reproduction Chromosome number diploid haploid Pairing of homologous chromosomes take place. (Yes/No) NO YES The daughter cells produced are always identical in terms of genetic material. (Yes/No) YES NO creates Somatic cells ( body cells) Sex cells ( gametes) Complete the table.