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Ladies And Gentlemen
Enzymes
*Definition
*Properties
*Function
Catalyst
Substance that increase the
velocity of a reaction.
Do not undergo any change.
Enzyme
Soluble colloid organic catalyst
Protein in nature except some
RNA catalytic enzymes
Accelerate the reaction
 Have the specificity
According to Summer and
Myrback –
Enzymes are simple or
combined proteins acting as
specific catalyst
Properties
Protein in nature (except some
catalytic RNA enzymes )
Fast a reaction 107 times more
 High specificity
 Act in optimum at pH(4-5)
and temperature at (35-40°C)
Sometimes needs inorganic and
organic compounds for action
Have a life of several weeks or
month then get broken down or
replaced by new
Do not alter the equibrillium
Function
Used for various purposes
Ex- Renin for cheese making
- Papain for meet cooking
- Penicillin synthetase for
penicillin production
Used for disease diagnosis
Ex-* AST(Aspertate Aminotransferase)
/SGOT(Serum glutamic oxaloacetic
transaminase )
Liver disease Myocardial infarction
*ALT(Alanine
Aminotransferase)/SGPT(serum
glutamic pyruvic transaminase )
Liver disease Kidney disease
*Lipase increased
Pancreatic tumor Stomach
& cholecystitis problems
*Alkaline phosphatase increased
Rickets Hyperparathy
roidism
Osteoblastic
carcinoma
Obstructive
jaundice
*Acetylcholine esterase increased
Nephrotic syndrome
*Lactate dehydrogenase increased
Tissue damage and organ failure
*Creatine kinase increased
Heart attack
Muscle injury
Strenuous exercise
Drinking too much alcohol
Taking certain medicine and supplement
 Treatment of certain diseases
Ex-
*Streptokinase
Myocardial infarction
Pulmonary embolism
Arterial thromboembolism
*Urokinase (clot busting )
Blood clot in the lung

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Enzyme (definition , properties and function of enzyme

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