BASAL ELECTRICAL RHYTHM

1. BASAL ELECTRIC RHYTHM
DEPARTMENT OF PHYSIOLOGY
SCHOOL OF MEDICAL SCIENCES AND
RESEARCH
SHARDA UNIVERSITY
Sanjog Bam
HUMAN BIOLOGIST
MSc Medical physiology

2. LEARNING OBJECTIVES
• Origin and introduction of slow wave potential
• Link between extrinsic and enteric nervous
system
• Peristalsis as integrated activity of the enteric
nervous system
• Smooth muscles electrophysiology
• Effect of Ach and epinephrine
• Electric recording in stomach

3. • Constant rhythmic depolarization are called pacemaker
potential/basal electric rhythm/electrical slow waves
• Chicken gizzard- Marimon 1907
• Frequency of slow waves depends on the section of the digestive
tube, Amplitude= 10- 20 mv
• Specialized pacemaker cells =Interstitial cells of Cajal

4. GI smooth muscles function as syncytium
Although enteric nervous system is independent of extrinsic nervous system but ANS can
greatly influence GI function

5. Ach / SPNO/VIP

6. • SMOOTH MUSCLES ELECTROPHYSIOLOGY
 Have almost continual slow , intrinsic
electrical activity along the membrane
 two types electrical waves : slow
waves and spike
Spike potential are the true action
potential
Slow waves usually do not causes
contraction by themselves
Rhythmic contraction of GI is determined by frequency of slow waves of membrane
potential
Frequency of slow waves= frequency of rhythm of contraction , if each waves trigger
spike potential leading contraction
Stomach= 3/min Illeum= 8-9/min
Duodenum=10-12/min colon= 3-4/min

9. summary
• Origin of basal electric rhythm
• Characteristics of BER
• Integration of BER with peristalsis
• Effect of Ach and epinephrine

10. THANK YOU