It is about locomotion of cells

2. LOCOMOTION OF CELLS
PRESENTED TO
Dr. Sania Munir
Presented By
Muhammad Saleem 104 (B)

3. OBJECTIVES
 Cell locomotion is important in physiological and pathological process.
 It includes cell migration during embryonic development.
 Movement of white blood cells in response to infection.
 This movement is also essential for survival, immune defense, and tissue repair.
 Locomotion helps us to move from one place to other.

4. CONTENTS
INTRODUCTION
TYPES OF LOCOMOTION OF CELLS
AMEBOID MOVEMENT
CILIARY MOVEMENT
REFERENCE

5. INTRODUCTION
 IMPORTANT TYPE THAT OCCURS IN THE
BODY IS THAT OF MUSCLE CELLS.
 IN SKELETAL , CARDIAC AND SMOOTH
MUSCLES.
 WHICH CONSTITUTE 50 % OF THE BODY
MASS.

6. • AMEBOID MOVEMENT
CILIARY MOVEMENT
•TYPES OF LOCOMOTION OF CELLS

7.  AMEBOID MOVEMENT

9. MECHANISM OF AMEBOID MOVEMENT
Two effects are essential for the continual formation
of new cell membrane:
i. First effect is attachment of pseudopodium to
surrounding tissues, so it becomes fixed in its leading
portion.

10. ”
“
ii. The second effect is to provide the energy required to
pull the cell body in the direction of the pseudopodium.
Continues….
 Large amount of actin protein in the cytoplasm.
 Network contracts bind with actin-binding protein
myosin.
 This whole process is energized by ATP.

11. CELLS EXHIBIT AMEBOID LOCOMOTION
1. White blood cells: they move out of the blood into the tissues
to form tissue microphages.
2. Fibroblast
3. Cell locomotion: is especially in development of the embryo
and fetus after fertilization of an ovum.
4. Embryonic cells
5. Sessile cells
6. Cancer cells (sarcomas).

12. CONTROL OF AMEBOID
LOCOMOTION=CHEMOTAXIS
Process that initiates ameboid locomotion is called chemotaxis.
Chemical substance that cause chemotaxis is called chemotactic
substance.
Cells exhibit ameboid locomotion when move towards source of
chemotactic substance known as positive chemotaxis.
Cells when move away from source of chemotactic show negative
chemotaxis.

13.  CILIARY MOVEMENT
 This movement occurs in cilia and flagella.

15. DIFFERENCE BETWEEN CILIA
AND FLAGELLA

16. CILIA
There are two types of cilia:
Motile cilia
Non-motile cilia (primary
cilia).

17. DIFFERENCE BETWEEN MOTILE
AND NON-MOTILE CILIA
I. Motile cilia II. Non-motile cilia

18. REFERENCE
 FROM=
 GUYTON AND HALL
 BY=
 GUYTON E.HALL