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LOCOMOTION OF CELLS
PRESENTED TO
Dr. Sania Munir
Presented By
Muhammad Saleem 104 (B)
OBJECTIVES
 Cell locomotion is important in physiological and pathological process.
 It includes cell migration during embryonic development.
 Movement of white blood cells in response to infection.
 This movement is also essential for survival, immune defense, and tissue repair.
 Locomotion helps us to move from one place to other.
CONTENTS
INTRODUCTION
TYPES OF LOCOMOTION OF CELLS
AMEBOID MOVEMENT
CILIARY MOVEMENT
REFERENCE
INTRODUCTION
 IMPORTANT TYPE THAT OCCURS IN THE
BODY IS THAT OF MUSCLE CELLS.
 IN SKELETAL , CARDIAC AND SMOOTH
MUSCLES.
 WHICH CONSTITUTE 50 % OF THE BODY
MASS.
• AMEBOID MOVEMENT
CILIARY MOVEMENT
•TYPES OF LOCOMOTION OF CELLS
 AMEBOID MOVEMENT
MECHANISM OF AMEBOID MOVEMENT
Two effects are essential for the continual formation
of new cell membrane:
i. First effect is attachment of pseudopodium to
surrounding tissues, so it becomes fixed in its leading
portion.
”
“
ii. The second effect is to provide the energy required to
pull the cell body in the direction of the pseudopodium.
Continues….
 Large amount of actin protein in the cytoplasm.
 Network contracts bind with actin-binding protein
myosin.
 This whole process is energized by ATP.
CELLS EXHIBIT AMEBOID LOCOMOTION
1. White blood cells: they move out of the blood into the tissues
to form tissue microphages.
2. Fibroblast
3. Cell locomotion: is especially in development of the embryo
and fetus after fertilization of an ovum.
4. Embryonic cells
5. Sessile cells
6. Cancer cells (sarcomas).
CONTROL OF AMEBOID
LOCOMOTION=CHEMOTAXIS
Process that initiates ameboid locomotion is called chemotaxis.
Chemical substance that cause chemotaxis is called chemotactic
substance.
Cells exhibit ameboid locomotion when move towards source of
chemotactic substance known as positive chemotaxis.
Cells when move away from source of chemotactic show negative
chemotaxis.
 CILIARY MOVEMENT
 This movement occurs in cilia and flagella.
DIFFERENCE BETWEEN CILIA
AND FLAGELLA
CILIA
There are two types of cilia:
Motile cilia
Non-motile cilia (primary
cilia).
DIFFERENCE BETWEEN MOTILE
AND NON-MOTILE CILIA
I. Motile cilia II. Non-motile cilia
REFERENCE
 FROM=
 GUYTON AND HALL
 GOOGLE
 BY=
 GUYTON E.HALL
Presentation1 [Recovered].pbl ^Jphysiology.pptx
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Presentation1 [Recovered].pbl ^Jphysiology.pptx

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  • 2. LOCOMOTION OF CELLS PRESENTED TO Dr. Sania Munir Presented By Muhammad Saleem 104 (B)
  • 3. OBJECTIVES  Cell locomotion is important in physiological and pathological process.  It includes cell migration during embryonic development.  Movement of white blood cells in response to infection.  This movement is also essential for survival, immune defense, and tissue repair.  Locomotion helps us to move from one place to other.
  • 4. CONTENTS INTRODUCTION TYPES OF LOCOMOTION OF CELLS AMEBOID MOVEMENT CILIARY MOVEMENT REFERENCE
  • 5. INTRODUCTION  IMPORTANT TYPE THAT OCCURS IN THE BODY IS THAT OF MUSCLE CELLS.  IN SKELETAL , CARDIAC AND SMOOTH MUSCLES.  WHICH CONSTITUTE 50 % OF THE BODY MASS.
  • 6. • AMEBOID MOVEMENT CILIARY MOVEMENT •TYPES OF LOCOMOTION OF CELLS
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  • 9. MECHANISM OF AMEBOID MOVEMENT Two effects are essential for the continual formation of new cell membrane: i. First effect is attachment of pseudopodium to surrounding tissues, so it becomes fixed in its leading portion.
  • 10. ” “ ii. The second effect is to provide the energy required to pull the cell body in the direction of the pseudopodium. Continues….  Large amount of actin protein in the cytoplasm.  Network contracts bind with actin-binding protein myosin.  This whole process is energized by ATP.
  • 11. CELLS EXHIBIT AMEBOID LOCOMOTION 1. White blood cells: they move out of the blood into the tissues to form tissue microphages. 2. Fibroblast 3. Cell locomotion: is especially in development of the embryo and fetus after fertilization of an ovum. 4. Embryonic cells 5. Sessile cells 6. Cancer cells (sarcomas).
  • 12. CONTROL OF AMEBOID LOCOMOTION=CHEMOTAXIS Process that initiates ameboid locomotion is called chemotaxis. Chemical substance that cause chemotaxis is called chemotactic substance. Cells exhibit ameboid locomotion when move towards source of chemotactic substance known as positive chemotaxis. Cells when move away from source of chemotactic show negative chemotaxis.
  • 13.  CILIARY MOVEMENT  This movement occurs in cilia and flagella.
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  • 16. CILIA There are two types of cilia: Motile cilia Non-motile cilia (primary cilia).
  • 17. DIFFERENCE BETWEEN MOTILE AND NON-MOTILE CILIA I. Motile cilia II. Non-motile cilia
  • 18. REFERENCE  FROM=  GUYTON AND HALL  GOOGLE  BY=  GUYTON E.HALL