4. INTRODUCTION
• Stomach ulcers, also known as gastric ulcers, are open
sores that develop on the lining of the stomach.
• Ulcers can also occur in part of the intestine just beyond
the stomach (duodenum).
• Stomach ulcers can affect people of any age, including
children, but mostly occur in people aged 60 or over.
• Men are more commonly affected than women.
22. OMEPRAZOLE
MECHANISM OF ACTION
Blocks H/K/ATPase of parietal
cells
Inhibit secretion of gastric acid
SIDE EFFECTS
• Diarrhea
• Headache
• Nausea and vomiting
23. BISMUTH SALICYLATES
MECHANISM OF ACTION
Inhibition of prostaglandin
synthase
Inflammation of stomach &
intestinal lining
SIDE EFFECTS
• Abdominal pain
• Anal discomfort
• Black/ hairy tongue
• Tarry/ clay colored stool
32. ANSWER THE QUESTIONS
Q. What is best used for detecting small or healing
ulcers?
a) Endoscopy
b) Barium radiography
c) Urea breath test
d) Abdominal CT.
33. Q. Complications of PUD include bleeding,
perforation, and penetration. Bleeding typically
manifests as_________
a)Melena
b)Clots
c)Coffee ground
d)Loose runny stools
34. Q. What often describes the pain of PUD?
a) Sharp, knife-like, radiates to right shoulder
b) Dull,achy, localized to stomach
c) Diffuse, joint arthritis
d) Burning, gnawing, radiates to the back
35. This Photo by Unknown Author is licensed under CC BY-NC
