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PRESENTED BY:
DR.PRAFULLA PATIL
WOUND
Definition:
 Wound is a discontinuity or break in the surface epithelium.
 A wound is simple when only skin is involved.
 It is complex when it involves underlying nerves, vessels and
tendons.
Types:
WOUND
OPEN
CONTUSION
ABRASION
HAEMATOMA
CLOSED
INCISED
LACERATED
PENETRATING
CRUSHED
TYPES:
WOUND
TIDY
UNTIDY
Types:
WOUND
ACUTE CHRONIC
HEALING OF WOUND:
 Healing by primary intention:occurs in clean incised
surgical wound.
 Healing by secondary intention: refers a wound which
is infected,discharging pus or wound with skin loss.
COMPONENTS OF WOUND
HEALING:
 INFLAMMATORY PHASE
 PROLIFERATIVE PHASE
 REMODELLING PHASE
 PHASE OF SCAR FORMATION
INFLAMMATORY PHASE
 Injury results in the release of inflammatory mediators
mainly histamines from platelets,mast cells and
graunlocytes.
 This results in increased capillary permiability.
 Later kinins and prostaglandins play a chemotactic role
for white cells and fibroblast.
 In 48 hours PMN leucocytes dominate.That leucocyte
play the role of scavengers by removing dead and
necrotic tissue.
PROLIFERATIVE PHASE:
 Between 3RD And 5TH Days,PMN leucocytes
 Monocytes increase (specialised scavenger)
 By 5th or 6 th day ,fibroblast appear,proliferate and give rise to
protocollagen which is converted in to collagen.
protocollagen
in presence of protocollagen hydroxylase,o2 ,ferrous
ion and ascorbic aacid.
collagen
 Epithelialisation : occurs mainly from the edges of the
wound by a process of cell migration and cell
umltiplication.
 This is mainly brought about by marginal basal cell.
 Thus within first 48 hour entire wound is reepithelised.
Remodelling phase:
 Starts after 4 days and completed within 14 days
 Brought about by specialised fibroblast they are called
myofibroblast because of their contractile nature.
 It is the natures way of reducing the size of defect,helping
in wound healing.
 Connective tissue formation:formation of granulation is the
most important process in wound healing.
Phase of scar formation:
 Following changes take place during scar formation:
 Collagen is increased
 Vascularity becomes less
 Epithelialisation continues
 Ingrowth of lymphatics and nerve fibres takes place
 Reodelling of collagen takes place with
cicatrisation,resulting in scar.
Complication of wound Healing:
 INFECTION
 UGLY SCAR
 KELOID
 INCISIONAL HERNIA
 PIGMENTATION
 MARJOLIN’S ULCER
General principles of management of open wounds:
WOUND
CLEANING AND
BANDAGE
SPLINT IF THERE IS
FRACTURE
SUTURING TRANSPORT
ACTIVE BLEEDING
STOP THE BLEEDING
IV
LINE,RESUSCITATION
 Admission and observation in hospital
 Monitoring of TPR ,BP
 Systemic antibiotic
 Injection TT
 Treatment in the form of cleaning ,dressing,or
suturing.
 Wound closure :by primary suturing and secondary
suturing
Factors affecting wound Healing:
 Age
 Vit c deficiency
 Diabetic patient
 Jaundiced and uraemic patients
 Cytotoxic drugs
 Generelised infection and local infection
 Corticosteroids
 Malnutrition
 Poor blood supply
 Hypoxia ,ionising radiation
 Faulty techniques of wound closure

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Wound

  • 2. Definition:  Wound is a discontinuity or break in the surface epithelium.  A wound is simple when only skin is involved.  It is complex when it involves underlying nerves, vessels and tendons.
  • 6. HEALING OF WOUND:  Healing by primary intention:occurs in clean incised surgical wound.  Healing by secondary intention: refers a wound which is infected,discharging pus or wound with skin loss.
  • 7. COMPONENTS OF WOUND HEALING:  INFLAMMATORY PHASE  PROLIFERATIVE PHASE  REMODELLING PHASE  PHASE OF SCAR FORMATION
  • 8. INFLAMMATORY PHASE  Injury results in the release of inflammatory mediators mainly histamines from platelets,mast cells and graunlocytes.  This results in increased capillary permiability.  Later kinins and prostaglandins play a chemotactic role for white cells and fibroblast.  In 48 hours PMN leucocytes dominate.That leucocyte play the role of scavengers by removing dead and necrotic tissue.
  • 9. PROLIFERATIVE PHASE:  Between 3RD And 5TH Days,PMN leucocytes  Monocytes increase (specialised scavenger)  By 5th or 6 th day ,fibroblast appear,proliferate and give rise to protocollagen which is converted in to collagen. protocollagen in presence of protocollagen hydroxylase,o2 ,ferrous ion and ascorbic aacid. collagen
  • 10.  Epithelialisation : occurs mainly from the edges of the wound by a process of cell migration and cell umltiplication.  This is mainly brought about by marginal basal cell.  Thus within first 48 hour entire wound is reepithelised.
  • 11. Remodelling phase:  Starts after 4 days and completed within 14 days  Brought about by specialised fibroblast they are called myofibroblast because of their contractile nature.  It is the natures way of reducing the size of defect,helping in wound healing.  Connective tissue formation:formation of granulation is the most important process in wound healing.
  • 12. Phase of scar formation:  Following changes take place during scar formation:  Collagen is increased  Vascularity becomes less  Epithelialisation continues  Ingrowth of lymphatics and nerve fibres takes place  Reodelling of collagen takes place with cicatrisation,resulting in scar.
  • 13. Complication of wound Healing:  INFECTION  UGLY SCAR  KELOID  INCISIONAL HERNIA  PIGMENTATION  MARJOLIN’S ULCER
  • 14. General principles of management of open wounds: WOUND CLEANING AND BANDAGE SPLINT IF THERE IS FRACTURE SUTURING TRANSPORT ACTIVE BLEEDING STOP THE BLEEDING IV LINE,RESUSCITATION
  • 15.  Admission and observation in hospital  Monitoring of TPR ,BP  Systemic antibiotic  Injection TT  Treatment in the form of cleaning ,dressing,or suturing.  Wound closure :by primary suturing and secondary suturing
  • 16. Factors affecting wound Healing:  Age  Vit c deficiency  Diabetic patient  Jaundiced and uraemic patients  Cytotoxic drugs  Generelised infection and local infection  Corticosteroids  Malnutrition  Poor blood supply  Hypoxia ,ionising radiation  Faulty techniques of wound closure