Aphea.Bio is a Belgian biotech company that develops microbial solutions to boost crop growth and reduce the use of chemical pesticides and fertilisers. The company has launched its first product, a biostimulant for wheat, in March 2021, and plans to release a biostimulant for maize and a biofungicide for wheat in 2024. The company announced a €70m Series C funding round, led by Innovation Industries, a Dutch VC firm focused on agtech and foodtech. Other investors include Korys Investments, BNP Paribas Fortis, the Bill & Melinda Gates Foundation, ECBF and Astanor. See more: bestpitchdeck.com/aphea-bio

1. MAY 2022

2. If you keep doing what
you did, you keep getting
what you got.
“
Modern agriculture comes at a
high sustainability price
caused by the extensive use of
fertilizer and chemical crop
protection products.
Challenge the
conventional.
Change the norm.
”

3. Aphea.Bio is dedicated to food
security and ensuring a safe
and healthy food chain,
providing reliable science-
based solutions
(biologicals) to build the
agriculture of the future:
sustainable, reliable and
profitable.
Farm
to Fork
Our
Mission
Aphea.Bio biologicals gain momentum
High commodity
and fertilizer
prices
Consumer
demand for safer
foods
Regulatory
pressure
Aphea.Bio is ready to succeed
with the right:
Team Technology Time in
history
Partners Location
Europe's leader in microbial solutions for agriculture

4. A fully integrated approach
to realize Aphea.Bio’s mission
Opening the untapped
microbial space
Implementing stringent
CoGs on row crops
High-throughput and
versatile R&D platform
combining innovative
technologies
Rich biocontrol and
biostimulant pipeline
Highly profitable
financial forecast: 30
forthcoming product
launches
Strategy validated:
two biostimulant
products close to market
entry
Broad and high-value
patent portfolio &
a major competitive
advantage
Diverse, skilled &
passionate team of
scientists and industry
professionals
30 2

5. Aphea.Bio’s R&D
Aphea.Bio is in a unique position to deliver novel and powerful solutions to the
market thanks to its innovative R&D platform which bundles several unique
technologies together to create a high-throughput pipeline for discovering new
biocontrol and biostimulant products focused on cereals.
Untapped
microbial
space
High-throughput
screening for
product concepts
Automated
in-planta
phenotype
assessment
Tailored production
& formulation
Extensive field trial
programme for validation
Product
development
Regulatory
& market
development
Product
launch
>100,000
strains
>10,000
strains
>1,000
strains
>100
strains
>10
strains
a ground-breaking
cost-efficient path from
discovery to market

6. Nutrient Use Efficiency (NUE) /Yield
Abiotic stress
Fusarium/ Rhizoctonia
Selective
Fusarium/
Zymoseptoria/ Puccinia
Powdery mildew/
Botrytis/ post-harvest
Aphids/Caterpillars
Non-selective
Discovery
Hit identification
Phase 1
Hit validation
Phase 2
Lead validation
Phase 3
Product development
Phase 4
Regulatory & Market
development
>10,000 strains ~1,000 strains ~100 strains ~10 strains ≥1 strains
FUNGICIDES
HERBICIDES
INSECTICIDES
BIOCONTROLS
BIOSTIMULANTS
Foliar
diseases
Soil
diseases
Wheat
Barley
Maize
Maize
Wheat
Wheat
Fruit & Veg
Field crops
Fruit & Veg
Different
crops
Target crop
Programme
41
15
26
68
2
5
7
5
9
2
1
Rich and
versatile pipeline
High-throughput and
automated platform
Broad pipeline
covering Biostimulants
and Biocontrols
Fast track/quick
implementation from
lab to field trial
validation
Our route to success: our rich product pipeline
# of strains
The numbers in the circle indicate the amount of leads currently being tested in each phase

7. Consistent and substantial yield increase under reduced fertilizer use of
Aphea.Bio’s product on wheat of 2.7 to 6.3% depending on the geographical zone.
2018 2019 2020 2021 2022 2023
Lead
selection
First field
trials
Scale-up
production
Registration
2024
Grain yield increase of soft wheat treated with Aphea.Bio’s product
per EU climatic zone (2019-2021)
Mediterranean 2.7%
South-East 4.2%
North-East 6.3%
Yield increase Win rate
67%
100%
75%
Aphea.Bio’s first wheat biostimulant
Launch

8. A significant yield increase under reduced fertilizer use of
Aphea.Bio’s product on maize exceeding 10%.
2020 2021 2022 2023 2024 2025
Lead
selection
First field
trials
Scale-up
production
Registration
Yield increase of the dry biomass of silage maize treated with
Aphea.Bio’s product per EU climatic zone (2021)
Maritime 5.0%
Mediterranean 10.0%
North-East 22.0%
Yield increase Win rate
67%
100%
100%
Aphea.Bio’s first maize biostimulant
Launch

9. Programme Segment Target market 2023 2024 2025 2026 2027 2028 2029 2030 2031
Biostimulant NUE Wheat
Barley, Durum,
Hybrid wheat
Maize
Abiotic stress Maize
Biofungicide Foliar diseases Wheat
Fruit & Vegetables
Soil diseases Field crops
Fruit & Vegetables
Bioherbicide Non-selective Various crops/
non crops
Selective for dicots Cereals
Bioinsecticide Insects F&V, cereals, sugar beet
G1 EU
G2 EU
G1 EU
G2 EU
G1 EU
G2 EU
G1 EU
G2 EU
G1 US
G1 US
G2 US
G1 US
G1 US
G1 US
G2 EU
G1 US
G1 US
G1 US
G2 US
G1 US
G2 US
G1 EU
G2 US G2 EU
G1 EU
G2 EU
G1 EU
G1 EU
G1 EU
G1 EU
1
5
3
2 2
7
6 6
8 8
14 14
4 5
12 12
5
4
9 9
13 13
13
13
10 10
15
16
11 11
Plans for 30 market introductions, based on 16 distinct active substances
Product launch calendar

10. (100,000,000)
-
100,000,000
200,000,000
300,000,000
400,000,000
500,000,000
600,000,000
700,000,000
800,000,000
900,000,000
1,000,000,000
2022 F 2023 F 2024 F 2025 F 2026 F 2027 F 2028 F 2029 F 2030 F 2031 F 2032 F 2033 F
EUR
sales ebitda cumulative cash
Profitable business model*
Financing needs
€50m
Finance & use of proceeds
67%
18%
15%
Use of
proceeds
R&D Expenses
& Capex
General &
Admin
Sales &
Marketing &
Regulatory
*probability weighted
(15,000,000)
(10,000,000)
(5,000,000)
-
5,000,000
10,000,000
2022 F 2023 F 2024 F 2025 F
sales ebitda
Sales and EBITDA
evolution 2022-2025
EUR

11. Benoit Lixon
Business Development
Master Agriculture Engineering
~15 years of relevant experience
Former Tessenderlo Group/Eastman
Inge Van Daele
Portfolio & ESG
PhD Applied Biological Sciences
~10 years of relevant experience
Former Biotalys/AgroSavfe
Geert Bossuyt
Finance
Masters in Accountancy and Finance
~25 years of relevant experience
Former Deutsche Bank/KBC
Steven Vandenabeele
Research
PhD Biotechnology
~15 years of relevant experience
Former BASF/Cropdesign
Ralph Beckers
Strategy
PhD in Biology
~30 years of relevant experience
Former Nufarm/Syngenta
Manuele Ricci
Development
Master Agronomy
~35 years of relevant experience
Former Lallemand/Bayer
A strong
management
team, with 150
years of joint
relevant
experience
Isabel Vercauteren
CEO
PhD Plant Biotechnology
~20 years of relevant experience
Former Bayer/DevGen

12. Company
founded
17 21
Field validated
leads ready for
development track
€19.8m
(Series B)
36
Regulatory
submission of
1st product
43
First sales +
B-Corp
certification
Break even
2017 2018 2019 2020 2021 2022 2023 2026 2027
The evolution of Aphea.Bio: milestones of our journey to success
Targeting
€50m
€7.7m
(Series A)
9 66 78
30
Potential
exit

13. Contact
Discover our story – driving the
revolution in biologicals
www.aphea.bio
info@aphea.bio
Technologiepark 21
9052 Gent | Belgium