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Developing healthy, native, natural, sustainable solutions
to improve animal growth and nourish the planet
At a fraction of the cost. Horizon Europe EIC Accelerator
Company Overview
Deep tech AI/ ML / agrifood startup HQ
in Toulouse, France. Offices in Boston.
Operating at the convergence of Digital
& Life Sciences
Based on 30 years of pioneering
university research in (i) glycemic
control in the gut-brain axis, (ii)
intestinal microbiota, and (iii) deep
insights into relational DBs and hybrid
AI/ML techniques.
Raised Series SEED €4.3M from private
investment + €4.8M non-dilutive funding
Background
Successfully demonstrated proof of concept
on geese: Aviwell’s DFMs increased the
incidence of fatty liver and induced a 250%
growth in 30% of geese, without force
feeding.
Aviwell is focused on larger markets starting
with €20B+ broiler FCR.
Recruited a team of 15 highly successful
physiologists, microbiologists, data
scientists and management professionals.
Assembled an internationally renowned
Scientific Advisory Board (SAB.)
History
Strong IP portfolio with 3 patents under
prosecution
Deep Know-How and Trade Secrets
Intellectual Property
Partnerships with world-leading
institutions in the EU and US
Broad contacts and MOUs with future
potential customers, supply partners
and distributors
Partnerships
Mission: To develop natural and sustainable solutions to improve animal
health to better nourish and provide FOOD SECURITY to the 8 billion people
on our planet ... And to do so a fraction of the cost.
2
Executive Team + Selected Partners
2
CEO
• Serial entrepreneur with
several successful exits
• 30+ years creating,
growing and managing
deep-tech start-ups
• Strong focus on profit and
maximizing shareholder
value
Mouli RAMANI
CSO
• PhD in Microbiology
and research director
at INSERM
• 30+ years as an
international specialist
in energy metabolism
and microbiota
• 200+ Publications
CTO
• PhD in Microbiology
• 20+ years in
microbiology, intestinal
microbiomes and
industrial production of
bacteria
• Deep Industry
Experience
Jeffrey CHRISTENSEN
VP Business Development
• Build and Grow
Technology Companies
• Startup Veteran
(including animal
Health and
Performance)
• Strong BD and
Operating background
David GILBERT
Partners:
Remy BURCELIN
Agrifood industry is searching for better solutions to
improve livestock production in an environmentally
friendly manner
Problems & Needs
3
• Food security is a growing need for ~8 Billion people worldwide
• Livestock production has plateaued and existing growth
strategies are insufficient and unsustainable
• Growth hormones, antibiotics and resource intensive activities
have a huge environmental impact resulting in greater water
use, deforestation, CO2 emissions, and chemical pollution of
arable lands and watersheds
• Consumers are placing a premium on natural and sustainable
food without antibiotics or GMOs
4
Farm Animal Growth has Plateaued
• After 20 to 30 Years of No to Slow
Phenotype Improvement...
• Agriculture Industry is Searching
for Better Solutions
5
Aviwell’s In Silico + In Vivo Biomimicry:
6
The solutions are in nature’s 2B-year-old library.
Our unique and differentiated approach will uncover these solutions.
Native & Adaptive
Biomimicry
• Target a Phenotype
• Measure Biological
Diversity to Unlock Key
Microbiota
Components
In Silico
• Our Discovery Platform
Leverages Deep
Sequencing of Microbiota
• Identifies Powerful
Multi-Strain Bacterial
Consortia Networks
In Vivo
• Direct Fed Microbial
• Fed 1 Time @Birth
• Fractional Dosage (e.g.,
1:200)
• High Performance (e.g.,
10% FCR)
Proprietary
Database
Algorithms
Hybrid AI + ML
Natal
Imprinting™
Consumed Once
Innovation: Aviwell’s Proprietary Platform
7
Metagenomics
Metatranscriptomics
Metaproteomics
Metabolomics
Culturomics
Diet
Environmental
Factors
Immune
System
Probiotics
Neurological
Disorders
Obesity
Inflammatory
Bowel
Disease
Antibiotics
Diabetes
Discovery Platform
Gut
Microbiome
MultiOmics
Proprietary
Database:
Bourget
Algorithms
Hybrid AI + ML
Bacterial Strain
Library
Natal
Imprinting™
Fed 1 Time @Birth
in silico in vivo
Animal Genomics
1. DFMs
(Nectar)
2. Platform
Services
(Aneto)
Products +
Services
First Product: DFM for Increased Poultry Feed Conversion Ratio
Building Discovery Platform Value
ü Species Agnostic:
Target any Species /
Phenotype
ü Control of Animal
Growth (FCR, BW,
Omega-3, etc...)
ü Identify Modes of
Action
Value
ü Biostatisticians
ü Bioinformaticians
ü Hybrid AI + ML
ü Novel Supervised
AI Algorithms
ü High Performance
DFMs
Discovery Platform:
Unique + Proprietary
ü Functional
Metagenomics
ü MultiOmics
Analyses
ü Microbiota
ü Public + Private
Datasets
Product Vision (e.g.): DFM for Broiler FCR Improvement
9
Aviwell Inside ™
ü A Single Dose at Birth + 10% better results
ü Sold Directly to Poultry Producer(s)
ü Native + Natural
Today
Aviwell Delivers Value + Cost Reduction
10
ü10% FCR Improvement: Less Feed Consumed = Smaller
Agricultural Footprint
üNatal Imprinting™: Long-Term + Lasting Benefits Resulting
in the Desired Phenotype
ü1 Dose vs 200: Delivered Once @ Birth vs. Continuously Fed
üReduced Time To Market: Higher Farm Flock Throughput
üImproved Flock Uniformity: Increased Processing Efficiency
Aviwell targets and affects commercially desirable phenotypes
with greater efficiency and efficacy.
FCR Improvement ~200 Doses One Dose
5% to 10%+:
High Performance
0% up to 5%:
‘Me-Too
Performance’
Aviwell’s Performance + Dosage (Savings) >>
Competition
11
Aviwell Solutions Increase Sustainability
12
Aviwell’s DFM solution provides a natural and sustainable
option for consumers, without antibiotics.
üDecreased Water consumption, Crop Land Use, Emissions
and Deforestation
üReduces Pollutants, Pesticides, and Waste products
üGreater Efficiency in Agriculture
üEnhances the Biological Diversity of the Animal Species
ü100% Native & Natural
2022 2023 2024 2025 2026 2027 2028
Cattle FCR $- $- $- $- $- $- $-
Layer Egg Rate $- $- $- $- $0.4 $1.3 $6.2
Discovery Platform $- $- $- $- $0.6 $3.0 $14.1
Aquaculture Omega3 $- $- $- $0.7 $3.5 $16.2 $61.0
Swine FCR $- $- $- $- $- $0.5 $2.3
Broiler FCR $- $- $0.2 $2.8 $20.2 $44.6 $172.2
Total $- $- $0.16 $3.48 $24.65 $65.53 $255.81
$-
$50
$100
$150
$200
$250
$300
Aviwell Revenue: $M vs Year
Attractive Revenue Potential
13
Revenue Drivers:
Ø DFM Product Sales by
Species Phenotype
Ø Discovery Platform
Subscription Services
14
Aviwell Approach: Species Agnostic
Aviwell can target key phenotypes in multiple species.
ü
ü
ü
+$20.7B Broiler FCR
+$20.8B Swine FCR
+$25B Aqua Omega-3/6 + Body Weight / FCR
+$35.2B Milk Quality Production
+$11.1B Egg Layer Rate
Proven Now Targeting Large Livestock Markets
~$300B
WW TAM
q Molecules for Chicken Performance
q In Silico multiOmics algorithms
q DFM for omega-3 in geese
Aviwell’s Strong and Growing IP Portfolio
ü INCREASING THE FATTY ACID
CONTENT OF LIVER AND RELATED
METHODS
ü MULTI-OMIC TECHNIQUES FOR THE
DECOVERY OF PRODUCT TARGETS
ü MICROBIAL COMPOSITIONS FOR
INCREASING POULTRY FEED
CONVERSION RATIO AND
ASSOCIATED METHODS
Aviwell Patents Filed
Potential Patents
• Functional Physiology and Molecular
Microbiology
• Biostatistical & Bioinformation Strategies
• AI / ML / Database Strategies
Know-How
• Bacterial Libraries and Databases
• SOPs
• Unique Animal Models for Validation
Trade Secrets
Successful Non Dilutive Fundraising
16
MADP (Deep Tech)
Awarded 1.6M€
Novaliv (Future Food)
Awarded for 700K€
European Innovation Council
Awarded 2.5M€ + “Series A”
4.8M€ Matching Equity
Raised 4.8M€ in 2022 in non dilutive grants to help push forward the science
Dilutive Fundraising
17
Use of Funds
1. Accelerate Poultry PoC Trials and define a
candidate DFM for improved FCR
2. Build out Discovery Platform to maximize
likelihood of successful DFM identification in
Broiler and Geese/ Duck.
3. Increase headcount in microbiology,
bioinformatics, and biostat organizations to
support #1 and #2
4. Build out business team to accelerate
commercial validation and partnerships (e.g.
regulatory pathway activities)
5. Grow IP Portfolio
6. Support G&A activities
7. Begin to raise company awareness in
anticipation of Series A
ü Series Seed Led by Tier 1 VCs: €4.3M
(Note 500K€ still open)
o Aviwell is strongly positioned for a Lead
in “Series A” raise in late 2024 (~6.8M€
already committed)
Aviwell Seed Pitch Deck

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Aviwell Seed Pitch Deck

  • 1. Developing healthy, native, natural, sustainable solutions to improve animal growth and nourish the planet At a fraction of the cost. Horizon Europe EIC Accelerator
  • 2. Company Overview Deep tech AI/ ML / agrifood startup HQ in Toulouse, France. Offices in Boston. Operating at the convergence of Digital & Life Sciences Based on 30 years of pioneering university research in (i) glycemic control in the gut-brain axis, (ii) intestinal microbiota, and (iii) deep insights into relational DBs and hybrid AI/ML techniques. Raised Series SEED €4.3M from private investment + €4.8M non-dilutive funding Background Successfully demonstrated proof of concept on geese: Aviwell’s DFMs increased the incidence of fatty liver and induced a 250% growth in 30% of geese, without force feeding. Aviwell is focused on larger markets starting with €20B+ broiler FCR. Recruited a team of 15 highly successful physiologists, microbiologists, data scientists and management professionals. Assembled an internationally renowned Scientific Advisory Board (SAB.) History Strong IP portfolio with 3 patents under prosecution Deep Know-How and Trade Secrets Intellectual Property Partnerships with world-leading institutions in the EU and US Broad contacts and MOUs with future potential customers, supply partners and distributors Partnerships Mission: To develop natural and sustainable solutions to improve animal health to better nourish and provide FOOD SECURITY to the 8 billion people on our planet ... And to do so a fraction of the cost. 2
  • 3. Executive Team + Selected Partners 2 CEO • Serial entrepreneur with several successful exits • 30+ years creating, growing and managing deep-tech start-ups • Strong focus on profit and maximizing shareholder value Mouli RAMANI CSO • PhD in Microbiology and research director at INSERM • 30+ years as an international specialist in energy metabolism and microbiota • 200+ Publications CTO • PhD in Microbiology • 20+ years in microbiology, intestinal microbiomes and industrial production of bacteria • Deep Industry Experience Jeffrey CHRISTENSEN VP Business Development • Build and Grow Technology Companies • Startup Veteran (including animal Health and Performance) • Strong BD and Operating background David GILBERT Partners: Remy BURCELIN
  • 4. Agrifood industry is searching for better solutions to improve livestock production in an environmentally friendly manner Problems & Needs 3 • Food security is a growing need for ~8 Billion people worldwide • Livestock production has plateaued and existing growth strategies are insufficient and unsustainable • Growth hormones, antibiotics and resource intensive activities have a huge environmental impact resulting in greater water use, deforestation, CO2 emissions, and chemical pollution of arable lands and watersheds • Consumers are placing a premium on natural and sustainable food without antibiotics or GMOs 4
  • 5. Farm Animal Growth has Plateaued • After 20 to 30 Years of No to Slow Phenotype Improvement... • Agriculture Industry is Searching for Better Solutions 5
  • 6. Aviwell’s In Silico + In Vivo Biomimicry: 6 The solutions are in nature’s 2B-year-old library. Our unique and differentiated approach will uncover these solutions. Native & Adaptive Biomimicry • Target a Phenotype • Measure Biological Diversity to Unlock Key Microbiota Components In Silico • Our Discovery Platform Leverages Deep Sequencing of Microbiota • Identifies Powerful Multi-Strain Bacterial Consortia Networks In Vivo • Direct Fed Microbial • Fed 1 Time @Birth • Fractional Dosage (e.g., 1:200) • High Performance (e.g., 10% FCR) Proprietary Database Algorithms Hybrid AI + ML Natal Imprinting™ Consumed Once
  • 7. Innovation: Aviwell’s Proprietary Platform 7 Metagenomics Metatranscriptomics Metaproteomics Metabolomics Culturomics Diet Environmental Factors Immune System Probiotics Neurological Disorders Obesity Inflammatory Bowel Disease Antibiotics Diabetes Discovery Platform Gut Microbiome MultiOmics Proprietary Database: Bourget Algorithms Hybrid AI + ML Bacterial Strain Library Natal Imprinting™ Fed 1 Time @Birth in silico in vivo Animal Genomics 1. DFMs (Nectar) 2. Platform Services (Aneto) Products + Services First Product: DFM for Increased Poultry Feed Conversion Ratio
  • 8. Building Discovery Platform Value ü Species Agnostic: Target any Species / Phenotype ü Control of Animal Growth (FCR, BW, Omega-3, etc...) ü Identify Modes of Action Value ü Biostatisticians ü Bioinformaticians ü Hybrid AI + ML ü Novel Supervised AI Algorithms ü High Performance DFMs Discovery Platform: Unique + Proprietary ü Functional Metagenomics ü MultiOmics Analyses ü Microbiota ü Public + Private Datasets
  • 9. Product Vision (e.g.): DFM for Broiler FCR Improvement 9 Aviwell Inside ™ ü A Single Dose at Birth + 10% better results ü Sold Directly to Poultry Producer(s) ü Native + Natural Today
  • 10. Aviwell Delivers Value + Cost Reduction 10 ü10% FCR Improvement: Less Feed Consumed = Smaller Agricultural Footprint üNatal Imprinting™: Long-Term + Lasting Benefits Resulting in the Desired Phenotype ü1 Dose vs 200: Delivered Once @ Birth vs. Continuously Fed üReduced Time To Market: Higher Farm Flock Throughput üImproved Flock Uniformity: Increased Processing Efficiency Aviwell targets and affects commercially desirable phenotypes with greater efficiency and efficacy.
  • 11. FCR Improvement ~200 Doses One Dose 5% to 10%+: High Performance 0% up to 5%: ‘Me-Too Performance’ Aviwell’s Performance + Dosage (Savings) >> Competition 11
  • 12. Aviwell Solutions Increase Sustainability 12 Aviwell’s DFM solution provides a natural and sustainable option for consumers, without antibiotics. üDecreased Water consumption, Crop Land Use, Emissions and Deforestation üReduces Pollutants, Pesticides, and Waste products üGreater Efficiency in Agriculture üEnhances the Biological Diversity of the Animal Species ü100% Native & Natural
  • 13. 2022 2023 2024 2025 2026 2027 2028 Cattle FCR $- $- $- $- $- $- $- Layer Egg Rate $- $- $- $- $0.4 $1.3 $6.2 Discovery Platform $- $- $- $- $0.6 $3.0 $14.1 Aquaculture Omega3 $- $- $- $0.7 $3.5 $16.2 $61.0 Swine FCR $- $- $- $- $- $0.5 $2.3 Broiler FCR $- $- $0.2 $2.8 $20.2 $44.6 $172.2 Total $- $- $0.16 $3.48 $24.65 $65.53 $255.81 $- $50 $100 $150 $200 $250 $300 Aviwell Revenue: $M vs Year Attractive Revenue Potential 13 Revenue Drivers: Ø DFM Product Sales by Species Phenotype Ø Discovery Platform Subscription Services
  • 14. 14 Aviwell Approach: Species Agnostic Aviwell can target key phenotypes in multiple species. ü ü ü +$20.7B Broiler FCR +$20.8B Swine FCR +$25B Aqua Omega-3/6 + Body Weight / FCR +$35.2B Milk Quality Production +$11.1B Egg Layer Rate Proven Now Targeting Large Livestock Markets ~$300B WW TAM
  • 15. q Molecules for Chicken Performance q In Silico multiOmics algorithms q DFM for omega-3 in geese Aviwell’s Strong and Growing IP Portfolio ü INCREASING THE FATTY ACID CONTENT OF LIVER AND RELATED METHODS ü MULTI-OMIC TECHNIQUES FOR THE DECOVERY OF PRODUCT TARGETS ü MICROBIAL COMPOSITIONS FOR INCREASING POULTRY FEED CONVERSION RATIO AND ASSOCIATED METHODS Aviwell Patents Filed Potential Patents • Functional Physiology and Molecular Microbiology • Biostatistical & Bioinformation Strategies • AI / ML / Database Strategies Know-How • Bacterial Libraries and Databases • SOPs • Unique Animal Models for Validation Trade Secrets
  • 16. Successful Non Dilutive Fundraising 16 MADP (Deep Tech) Awarded 1.6M€ Novaliv (Future Food) Awarded for 700K€ European Innovation Council Awarded 2.5M€ + “Series A” 4.8M€ Matching Equity Raised 4.8M€ in 2022 in non dilutive grants to help push forward the science
  • 17. Dilutive Fundraising 17 Use of Funds 1. Accelerate Poultry PoC Trials and define a candidate DFM for improved FCR 2. Build out Discovery Platform to maximize likelihood of successful DFM identification in Broiler and Geese/ Duck. 3. Increase headcount in microbiology, bioinformatics, and biostat organizations to support #1 and #2 4. Build out business team to accelerate commercial validation and partnerships (e.g. regulatory pathway activities) 5. Grow IP Portfolio 6. Support G&A activities 7. Begin to raise company awareness in anticipation of Series A ü Series Seed Led by Tier 1 VCs: €4.3M (Note 500K€ still open) o Aviwell is strongly positioned for a Lead in “Series A” raise in late 2024 (~6.8M€ already committed)