1. Natriuretic peptides increase oxygen-carrying
capacity of blood
Olli Arjamaa, MD, PhD
Specialist in Ophthalmology
Lecturer in Animal Physiology, University of Turku, Finland
Lecturer in Medical Physiology, University of Oulu, Finland
+358 405125452
olli.arjamaa@utu.fi
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4. Hypoxic conditions stimulate the release of NT-proBNP from the human
retinal pigment epithelium (RPE) cell culture without any stretch or
pressure changes.
Aaltonen V, Kinnunen K, Jouhilahti EM, Nikinmaa M, Kaarniranta K and
Arjamaa O. 2014. Acta Ophthalmol. 92: 740-744.
5. Strong extrarenal effects
In nephrectomized rats, ANP (=ANF) infusion increased hematocrit (Hb concentration) and
decreased plasma volume. The change was due to the efflux of fluid from capillaries. With the
sodium nitroprusside that caused a similar blood pressure decrease such changes were not seen
(Almeida et al. 1986. Life Sci 39: 1193-99).
6. Arjamaa, O. 2017. Physiology of natriuretic peptides. Chapter 4. In: Advances in
Medicine and Biology. Editor: Leon V. Berhardt, pp. 101-113. Nova Science
Publishers, Inc. USA.
7. My publications related to natriuretic peptides and oxygen
Arjamaa, O. and Nikinmaa, M. 2009. Review. Natriuretic peptides in hormonal regulation of hypoxia responses. Am. J. Physiol. 296: R257-
R264.
Arjamaa, O. and Nikinmaa, M. 2010. Letter to the Editor. Does the wall stress alone stimulate the natriuretic peptide system? Hypertension
56: e175.
Arjamaa, O. and Nikinmaa, M. 2011. Review. Hypoxia regulates the natriuretic peptide system. Int. J. Physiol. Pathophysiol. Pharmacol. 3:
191-201.
Arjamaa, O. and Nikinmaa, M. 2012. Letter to the Editor. Does hypoxia directly regulate the natriuretic peptide system? Int. J. Cardiol. 154:
372.
Arjamaa, O. and Nikinmaa, M. 2013. Editorial. Oxygen and natriuretic peptide secretion from the heart. Int. J. Cardiol. 167: 1089-1090.
Arjamaa, O. 2014. Minireview. Physiology of natriuretic peptides – the volume overload hypothesis revisited. World J. Cardiol. 6: 4-7.
Aaltonen, V., Kinnunen, K., Jouhilahti, E.-M., Peltonen, J., Nikinmaa, M., Kaarniranta, K. and Arjamaa, O. 2014. Hypoxic conditions stimulate
the release of B-type natriuretic peptide from human retinal pigment epithelium cell culture. Acta Ophthalmol. doi:10.1111/aos.12414.
Arjamaa, O., Vuolteenaho, O., Kivi, E. and Nikinmaa, M. 2014. Hypoxia increases the release of salmon cardiac peptide (sCP) from the heart of
rainbow trout (Oncorhynchus mykiss) under constant mechanical load in vitro. Fish Biol. Biochem. 40: 67-73.
Heinonen, I., Luotolahti, I., Vuolteenaho, O., Nikinmaa, M., Saraste, A., Hartiala, J., Koskenvuo, J., Knuuti, J. and Arjamaa, O. 2014.
Circulating N-terminal brain natriuretic peptide and cardiac function in response to severe acute systemic hypoxia in healthy humans. J. Transl.
Med. 12: 189-196.
Arjamaa, O. 2017a. Letter to the Editor. Myocardial infarction and N-teminal pro-brain natriuretic peptide. Am. J. Cardiol. 120: 1697.
Arjamaa, O. 2017b. Physiology of natriuretic peptides. Chapter 4. In: Advances in Medicine and Biology. Editor: Leon V. Berhardt, pp. 101-113.
Nova Science Publishers, Inc. USA.
