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Causes of hemolysis HY

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Rickettsia Rickettsii
Rickettsia Rickettsii

Intravascular hemolysis can be caused by conditions like disseminated intravascular coagulation, transfusion reactions, and certain infections that damage red blood cells inside blood vessels. Extravascular hemolysis occurs outside of blood vessels and can result from red blood cell enzyme deficiencies, genetic hemoglobin disorders, membrane defects, hypersplenism, autoimmune responses, and some infections.

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Causes of hemolysis Intravascular hemolysis • Microangiopathic hemolytic anemia (eg, DIC) • Transfusion reactions • Infections (eg, clostridial sepsis) • Paroxysmal nocturnal hemoglobinuria • Intravenous Rho(D) immunoglobulin infusion Extravascular hemolysis • Intrinsic RBC enzyme deficiencies (eg, G6PD) • Hemoglobinopathies (eg, sickle cell, thalassemia) • Membrane defects (eg, hereditary spherocytosis) • Hypersplenism, intravenous immunoglobulin infusion • Warm- or cold-agglutinin autoimmune hemolytic anemia (most cases) • Infections (eg, Bartonella, malaria)

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Causes of hemolysis HY

  • 1. Causes of hemolysis Intravascular hemolysis • Microangiopathic hemolytic anemia (eg, DIC) • Transfusion reactions • Infections (eg, clostridial sepsis) • Paroxysmal nocturnal hemoglobinuria • Intravenous Rho(D) immunoglobulin infusion Extravascular hemolysis • Intrinsic RBC enzyme deficiencies (eg, G6PD) • Hemoglobinopathies (eg, sickle cell, thalassemia) • Membrane defects (eg, hereditary spherocytosis) • Hypersplenism, intravenous immunoglobulin infusion • Warm- or cold-agglutinin autoimmune hemolytic anemia (most cases) • Infections (eg, Bartonella, malaria)