Paper presentation at the London Computing Conference 2017
Abstract- Artificial Intelligence (AI) and Machine Learning (ML) have shown great promise in the field of medicine and healthcare. This paper seeks to understand how AI and ML have been applied to the realm of patient care within the context of chronic disease, with a specific focus on Inflammatory Bowel Disease (IBD). First we present an overview of IBD, highlighting the nature of the disease and some of the challenges the various stakeholders face within the framework of outpatient care. Then we outline the current state of research into the application of AI and ML in general clinical care and in relation to IBD. After which we explore how both AI and ML have been utilized to help with the outpatient treatment of chronic illnesses which share similar challenges to that of IBD, such as Diabetes, mental health conditions and Parkinson ’s disease, so as to gain precedent into how similar techniques may be used to assist in IBD outpatient support. Finally, we discuss the work that has passed and explore the prospect of future research into the field.
Intelligent Systems and Inflammatory Bowel Disease: Exploring the Potential for Outpatient Support
1. Nader Al-shamma
Dr Ali Jwaid
Intelligent Systems and Inflammatory Bowel Disease:
Exploring the Potential for Outpatient Support
Computing Conference 2017
18-20 July 2017 | London UK
2. What is the problem?
“[…]a diagnosis of IBD is not a death sentence, but it
can often be a life sentence. [..] For patients and their families, the impact
of a chronic disease will bring changes in their personal, social and
emotional lives.”
Thomas, G (2008)
Counselling and Reflexive Research in Healthcare : Working Therapeutically with Clients
with Inflammatory Bowel Disease, Jessica Kingsley Publishers, London.
The solution?
Can advances in machine learning and artificial intelligence help tackle some of the challenges faced by those
affected by IBD?
3. How big is the problem?
Global rates of IBD are increasing, as a
result the illness is fast becoming an
international problem.
3 Million
Across
Europe
€4.6 to €5.6
Billion
Per year
300,000
In
UK
4. Areas of focus:
Diet and Nutrition
Lifestyle and
Self-management
Patient Monitoring
and Insight
5. Applied AI and Machine Learning: Application Domain
Prognostics
Diagnostics Outpatient Support (?)
6. AI and Machine Learning in Action
Diagnosis:
● Matalka et al. (2013) Artificial Neural Network (ANN) and a Probabilistic Neural Network(PNN) used to diagnose IBD.
● 98.31% Rate of Accuracy.
Prognosis:
● Waljeeet al. 2010 used Random Forest to analysis laboratory data to determinethe success of thioprinetreatment.Results: Area under Receiver Operating Characteristic
(AUROC) curve of 0.856 vs AUROC of 0.594 from traditional testing techniques.
● Hardalaç et al 2015 used ANN to determine the success of treating patients with the immunosuppressant drug Azathioprine. Taking into
account patient health and lifestyle metrics. Results: predict the efficacy of Azathioprine use with a precision of 79%.
Outpatient Support: ?????
9. Credits
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Aleo Free Font
Lato Font
http://www.fontsquirrel.com/fonts/lato
FONTS
Images:
• E-healthcare concept with hand holding smart phone #115660297, Author:
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Editor's Notes
Introduction
MSc Student @ NTU
Aim: Understand the potential for AI and ML to support outpatients with a chronic illness
Imagine what it is like to have IBD
What is IBD
How is it managed?
What are the challenges
Little known about the optimum self management techniques
changes to lifestyle
managing stress
Medication adherence
Consensus is that diet affects the symptoms and status of the illness. Zero consensus on what the right diet is!
Clinical staff see patients for checkups and rely on their memory, no clean data for how they are doing.
What avenues of research are being explored
How is AI and Machine learning supporting
Big focus on Diagnostics and Prognostics
Less research on outpatient support.
Not found anything relating to IBD and outpatient support
We have the technology, we just need to collect the data!
Working on the first step to collect the data by building an app.