The slides about Lassa fever. It showed that how virus infectious to human.

1. Submitted to:
Dr. Ghulam Shabir
Submitted By:
Muhammad Amir
Roll number: BSBTE-19-40

2.  Lassa fever an zoonotic, Or acute viral illness
 Viral haemorrhagic fever disease
 That’s spread by the common West African rat.
 1969, discovered in Lassa Town of Nigerian
 Cases :300,000
 Deaths: 5,000
 Two missionary Nurses died.

3. An acute viral haemorrhagic illness caused by
Lassa virus (arenavirus).
Classifucation
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Arenaviridae
Genus: Mammarenavirus
Species: Lassa mammarenavirus
Genome sizes: 3402 nucleotide long

4. Transmitted to humans by:
 contaminated food with infected mice
urine or faeces.
 Person-to-person transmission
 Lacking adequate infection control
measures

5. STRUCTURE OF LASSA VIRUSES
https://nursinganswers.net/essays/lassa-fever-essay.php
• Ss RNA virus
• Enveloped virus
• 120nm in diameter
• Spherical to
pleomorphic shape

9.  Ribavirin, an antiviral drug
 Maintenance of fluid
 Maintenance of oxygenation
 Maintenance of blood pressure
 Treatment of any other complicating infections.

12.  https://www.webmd.com/a-to-z-guides/lassa-fever-overview
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC112216/
 https://vhfc.org/diseases/lassa/
 https://www.researchgate.net/figure/Arenavirus-life-cycle-1-
Cellular-entry-is-mediated-by-different-cellular-receptors-
a_fig3_277413510
 https://africacdc.org/disease/lassa-fever/
 https://www.cdc.gov/vhf/lassa/treatment/index.html#:~:text=Riba
virin%2C%20an%20antiviral%20drug%2C%20has,the%20course
%20of%20the%20illness.