Lassa fever is a viral hemorrhagic illness spread by rodents in West Africa. It was first discovered in 1969 in Nigeria, where it has caused over 300,000 cases and 5,000 deaths. The Lassa virus is an arenavirus transmitted through contact with infected rodent urine or feces. It can also spread between humans through direct contact with bodily fluids. Treatment focuses on supportive care and the antiviral drug ribavirin.

1. Submitted to:
Dr. Ghulam Shabir
Submitted By:
Muhammad Amir
Roll number: BSBTE-19-40

2.  Lassa fever an zoonotic, Or acute viral illness
 Viral haemorrhagic fever disease
 That’s spread by the common West African rat.
 1969, discovered in Lassa Town of Nigerian
 Cases :300,000
 Deaths: 5,000
 Two missionary Nurses died.

3. An acute viral haemorrhagic illness caused by
Lassa virus (arenavirus).
Classifucation
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Arenaviridae
Genus: Mammarenavirus
Species: Lassa mammarenavirus
Genome sizes: 3402 nucleotide long

4. Transmitted to humans by:
 contaminated food with infected mice
urine or faeces.
 Person-to-person transmission
 Lacking adequate infection control
measures

5. STRUCTURE OF LASSA VIRUSES
https://nursinganswers.net/essays/lassa-fever-essay.php
• Ss RNA virus
• Enveloped virus
• 120nm in diameter
• Spherical to
pleomorphic shape

9.  Ribavirin, an antiviral drug
 Maintenance of fluid
 Maintenance of oxygenation
 Maintenance of blood pressure
 Treatment of any other complicating infections.

12.  https://www.webmd.com/a-to-z-guides/lassa-fever-overview
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC112216/
 https://vhfc.org/diseases/lassa/
 https://www.researchgate.net/figure/Arenavirus-life-cycle-1-
Cellular-entry-is-mediated-by-different-cellular-receptors-
a_fig3_277413510
 https://africacdc.org/disease/lassa-fever/
 https://www.cdc.gov/vhf/lassa/treatment/index.html#:~:text=Riba
virin%2C%20an%20antiviral%20drug%2C%20has,the%20course
%20of%20the%20illness.