knowledge for youth

1. CORONA
PANDEMIC
AWARNESS
Presentation by
Tooba Kanwal

2. COVID-19 ALERT
Region Asia, Country Pakistan

3. Key Points
The 2019–20 coronavirus pandemic is an ongoing pandemic of
coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2).
01
Structure of covid-19
02
The new coronavirus is a respiratory virus which spreads primarily
through droplets generated when an infected person coughs or
sneezes, or through droplets of saliva or discharge from the nose.
Symptoms:
03
To protect yourself, clean your hands frequently with an alcohol-based
hand rub or wash them with soap and water.
Safety Precautions
04
Introduction
Coronaviruses are a group of related RNA viruses that cause diseases
in mammals and birds. In humans, these viruses cause respiratory tract
infections that can range from mild to lethal.

4. Introduction
RNA virus family in the Nidovirals order
Effective pathogenic viruses in humans and livestock
The suffix corona derives from the Latin term for crown
Identified after "crown like" virus appearance
Four classifications:
I. Alpha
II. Beta
III. Gamma
IV. Delta

5. Introduction
Human corona infections are pathogens of the alpha and beta corona
Medium-scale viruses with positive-stranded RNA
 A quite broad genome of RNA viruses
Corona viruses are a wide family of viruses that trigger
disease in humans and other mammals and birds that circulate.
Animal corona virus will occasionally spread to humans, and only spread to
individuals.
Zoonotic corona virus disorder (COVID- 2019)
Hosts reservoirs and mammals and infected animals
infected birds and mammals
Bats are carriers with the greatest number with corona virus genotyp
es
Epidemics may occur when transferring viruses from one species to
another
May induce protein mutations that enable viruses to bind to cells

6. Introduction
Humans
Human corona viruses cause respiratory
infections and gastrointestinal infections
Estimated at 5-10% of all upper respiratory infections in adults
Corona virus mutations may be an significant source of human epidemics
An historical analysis of infections
Significant acute respiratory syndrome(SARS) 2002-2003
Guangdong, China Province
Corona virus beta
Transmitted to person from bats to civets
The epidemic began in February 2003 and continued until July 2003.
About 8,000 incidents in all, 774 deaths at ~9.6 percent

7. Introduction
Respiratory Syndrome in the Middle East(MERS)2012
Saudi Arab
Virus beta corona
Transferred from camels to humans
More than 2,400 cases, 858 deaths, ~34.4 percent fatality
Novel Virus Corona(Covid-19), 2019
Wuhan, chinese hubei province
Seventh Crona virus identified to induce human illness .
Novel beta coronavirus.
Spread from snakes, but more likely from bats.
Animal market.

8. WHO Timeline - COVID-19
2019.032020.022020.012019.12 2019.04
3.01-3.15 Deeply concerned
both by the alarming levels of
spread and severity, and by
the alarming levels of
inaction, WHO made the
assessment that COVID-19
can be characterized as a
pandemic.
3.16-3.31 WHO and partners
launch the Solidarity Trial, an
international clinical trial that
aims to generate robust data
from around the world to find
the most effective treatments
for COVID-19.
2.01-2.10 WHO releases the
international
community's Strategic
Preparedness and Response
Plan to help protect states
with weaker health systems.
2.11-2.15 WHO convened
a Research and Innovation
Forum on COVID-19,
attended by more than 400
experts and funders from
around the world, which
included presentations
by George Gao, Director
General of China CDC, and
Zunyou Wu, China CDC's
chief epidemiologist
1.01-1.15 WHO had set up
the IMST (Incident
Management Support Team)
across the three levels of the
organization: headquarters,
regional headquarters and
country level, putting the
organization on an
emergency footing for dealing
with the outbreak.
1.16-1.31 WHO reported on
social media that there was a
cluster of pneumonia cases –
with no deaths – in Wuhan,
Hubei province.
12.01-12.31 Wuhan
Municipal Health
Commission, China,
reported a cluster of cases
of pneumonia in Wuhan,
Hubei Province. A novel
coronavirus was eventually
identified.
4.00 Second wave of corona
is to be start in different
countries which cause major
effect on 3rd world countries.
4.00 WHO predicted that 3rd
wave will be arise in winters
which cause major loss and
this pandemic will leave its
effect for 2 years
COVID-19
Progress st eps: An updated version was published on 29 June 2020

9. Current Situation In Pakistan
Data Update

10. Current Situation In Pakistan
Data Update

11. Current Situation In Pakistan
Data Update

12. Crystal Structure Of Covid-19
Structure
• The Chinese scientists first reported the genome and with overseas cooperation obtained the crystal structure of the
three-dimensional novel COVID-19 key protease (M pro) The M pro is a crucial function in the synthesis of poly
proteins and the maturation of viruses, hence it is considered a desirable goal for the production of antiviral. M pro
is commonly documented to be deactivated by HIV-1 protease inhibitors. The Chinese scientists first reported
genome and have now acquired M pro 's structure. The crystal structure comprises 306 amino acids in the three
regions, in 8-101 residues in the first region depicted in gray, 102-184 residues in the second region in green, and
201-303 residues in the third area in gold.
• The third region is connected to second region through a long loop region contains 185-200 residues. Mass
spectroscopy determined the weight of COVIid-19 M Pro is 33797.0 Da. Theoretical studies confirmed the weight is
33796.8 Da.

13. Crystal Structure Of Covid-19
SARS Corona
Virus
This has a pathogenesis, as it creates diseases of the upper and lower
respiratory tract as well as Gastroenteritis.
Recent history:
The SARS infection of 2003 exploded in more than 8,000 cases, around 10
percent of which ended in death.
In September 2012, what is suspected to be the sixth novel kind of coronavirus,
tentatively referred to as Novel
Corona virus 2012, was identified in Qatar and Saudi Arabia as being identical
to SARS (but also distinct from the common cold corona virus).

14. Crystal Structure Of Covid-19
How is Novel Corona
virus transmit?
• All the clusters of cases reported so far were spread amongst members of the family or in a
health care environment, the WHO said in an update.
• Human to human communication took place in at least some of these clusters,
although the precise transmission mechanism is unclear.
• That means it's not yet known how humans contract the virus. But, experts say, there has
been no evidence of cases beyond the clusters into communities.

15. Symptoms
PANDEMIC (COVID-19)
Cough Fever Shortness
Of Breath
Sore Throat

16. Stages:
Aches and pain, Sore throat, Diarrhoea,
Conjunctivitis, Headache, Loss of taste or smell,
Rash on skin or discolouration of fingers and toes.
Initial Stage
Mild Stage
Difficuiculty in breathing or shortness of
breath, Chest pain or pressure, Loss speech or
movement .
Critical Stage
Fever, Dry cough, Tiredness and breathing
issues

17. Safety Precautions
Social
Distancing
2m
Wash your hands-on regular basis
Avoid touching your face, nose and eyes
Self isolate yourself if you are having
minor symptoms
Avoid crowded places
Wear mask
Seeking medical advice

18. • Tissue Paper
• Face Mask
• Sanitizer Bottle
• Medicines
1. Panadol
2. Cough Syrups
3. Pain killers
4. Breathing Steam
Mobilizers
5. Boost up Your
immunity by Eat
healthy
6. Daily Exercise

19. How Covid-19 Spreads And Effect
1 2
Imported
COVID-19
PANDEMIC
Affects different people in
different ways:
Most infected people will
develop mild to moderate
illness and recover
without hospitalization.
 The virus mainly spread from person
to person through close contact.
 Through respiratory droplets
produced when infected person
coughs, sneezes, or talks.
 COVID-19 maybe people who are
not showing symptoms.
 In droplet transmission, aerosols can
be released in several ways including
breathing, talking,
laughing,sneezing,coughing,singing
and shouting.
 Corona Virus infects the lining of
throat, airways and lungs.
 Through touching those objects
which are touches by an infected
person.
How Covid-19 Spreads
And Effects

20. All the clusters of cases reported so far were spread amongst members of
the family or in a health care environment, the WHO said in an update.
.
How is Novel Corona virus transmit?
Human to human communication took place in at least some of these clusters,
although the precise transmission mechanism is unclear.
That means it's not yet known how humans contract the virus. But, experts say, there has
been no evidence of cases beyond the clusters into communities.
We Together
Safe the
World

21. Role Of Community Development In Covid-19
PANDEMIC
No handshake
Maintain Social Distance
No Social Gathering
How To Prevent An Outbreak
Wear Mask
Wash hands with Soap
• Use of mobile technology
and social media
• Working on grass root levels
• Role of NGO’s to stop
stigmatization
• To extend the borders for
helping the overlooked
population
• Webinars for awareness
about isolation and
quarantine

22. Dr. Ryan cautioned against reactive measures
saying, "It is not the time for countries to
move toward mitigation," only if they are able
to affect the course of the transmission of
COVID-19. This could overwhelm a country's
healthcare system.
"All countries need to review their strategies
now," he added.
"Pandemic is not
a word to use
lightly or
carelessly. It is a
word that, if
misused, can
cause
unreasonable
fear, or
unjustified
acceptance that
the fight is over,
leading to
unnecessary
suffering and
death."

23. Just Boost up
Your Immunity
First thing you do
If you got Infected
Don’t Panic

24. World Health
Organization Stated
that :
Stay aware of the latest
information on the COVID-19
outbreak, available on the WHO
website and through your
national and local public health
authority. Most countries around
the world have seen cases of
COVID-19 and many are
experiencing outbreaks.
Authorities in China and some
other countries have succeeded
in slowing their outbreaks.
However, the situation is
unpredictable so check regularly
for the latest news.

25. Reminder
2m

26. Stay Home And Stay Safe

27. We collected all the data from following references as mention below:
• https://www.worldometers.info/coronavirus/country/pakistan/
• https://www.who.int/emergencies/diseases/novel-coronavirus-2019
• https://www.ehstoday.com/health/media-gallery/21126031/8-quotes-from-the-world-health-organizations-covid19-media-briefing
• https://www.ehstoday.com/health/media-gallery/21126031/8-quotes-from-the-world-health-organizations-covid19-media-briefing
• https://www.google.com/search?sxsrf=ALeKk01yB9k_Mswxuys82zB9GKZFdFQi3Q%3A1594336873517&ei=aaYHX7mQH8uua-
KsmugI&q=structure+of+coronavirus+pandemic&oq=structure+of+coronavirus+pandemic&gs_lcp=CgZwc3ktYWIQAzIECCMQJ1AAWABg-
dADaABwAHgAgAH1AYgB9QGSAQMyLTGYAQCqAQdnd3Mtd2l6&sclient=psy-
ab&ved=0ahUKEwj56P3Xp8HqAhVL1xoKHWKWBo0Q4dUDCAw&uact=5
• https://www.google.com/search?sxsrf=ALeKk02V9XNR2m-a6sTp6ZGPCWJG2Hfu0Q%3A1594336833029&ei=QaYHX-
S1AYmwa9XFlcgI&q=introduction+to+coronavirus+pandemic&oq=intro+duction+to+corona&gs_lcp=CgZwc3ktYWIQARgCMgQIIxAnMgQIABAN
MgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANUABYAGCVImgAcAB4AIAB8wGIAfMBkgEDMi0xm
AEAqgEHZ3dzLXdpeg&sclient=psy-ab
• https://www.google.com/search?sxsrf=ALeKk02V9XNR2m-a6sTp6ZGPCWJG2Hfu0Q%3A1594336833029&ei=QaYHX-
S1AYmwa9XFlcgI&q=introduction+to+coronavirus+pandemic&oq=intro+duction+to+corona&gs_lcp=CgZwc3ktYWIQARgCMgQIIxAnMgQIABAN
MgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANMgQIABANUABYAGCVImgAcAB4AIAB8wGIAfMBkgEDMi0xm
AEAqgEHZ3dzLXdpeg&sclient=psy-ab
References

28. THANK YOU
To All Of You