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Invention Journal of Research Technology in Engineering & Management (IJRTEM)
ISSN: 2455-3689
www.ijrtem.com Volume 2 Issue 3 ǁ March. 2018 ǁ PP 13-16
| Volume 2 | Issue 3 | www.ijrtem.com | 13 |
Text Extraction Engine to Upgrade Clinical Decision Support
System
Merve Kevser Gökgöl 1
, Zeynep Orhan 2
, Ajla Kirlić 3
1,2
Department of Information Technologies, International Burch University, Sarajevo, Bosnia and Herzegovina
3
Department of Engineering, American University in Bosnia and Herzegovina
ABSTRACT : New generation technological improvements lead patients to search their symptoms and
corresponding diagnosis on online resources. In this study, it is aimed to develop a machine learning model to
suit in different availability of users. Most of the current systems allow people to choose related symptom in web
interfaces. In addition to these applications it is aimed to implement a new technique which extracts the text-based
symptoms and its related parameters such as, severity, duration, location, cause, accompanied by any other
indicators. This study is applicable for patient`s everyday language statements besides medical expression of
symptoms for corresponding symptoms which is also supporting initial clinical decision system. Extracted terms
are analyzed for matching diagnosis where an accuracy of 90% has been accomplished.
KEYWORDS : Medical diagnosis, symptom extraction, public healthcare, machine learning
I. INTRODUCTION
The era of digitization has led computers to become the real face of handling commercial processes across a wealth
of industries. As institutions today specifically in the medical domain have resorted to these virtual machines for
realizing their goals, more and more medical data is being generated on a continuous basis (Davis et al., 2008).
Current systems are challenging to optimize the utilization of existing medical data resources in automated
diagnostics. The detection and interpretation of pathological conditions usually required large number of experts
available, however the number of experts is sometimes not enough, and other problems may appear such as
disagreement among experts (Spyns et al., 1998).
The electronic patient records contains a rich source of valuable clinical information, which could be used for a
wide range of automated applications aimed at improving the health care process, such as alerting for potential
medical errors, generating a patient problem list, and assessing the severity of a condition (Friedman et al., 2004).
However, these applications are not applicable since large amount of information is in textual form (Tange et al.,
1998).
II. METHODOLOGY
In this study, process of data collection allows patients to enter their symptoms by typing in everyday language.
Therefore, to increase the accuracy firstly it is required to clean and eliminate insignificant words, such as stop
words and vague abbreviations. From highest to lowest, predicted diseases are printed on the screen with matched
symptoms.
Data Set : We have considered two sources for disease data. One of them is Mayo Clinic website (Mayoclinic.org.,
(2018)) which contains highly detailed information about diseases: disease overview, symptoms, when to see a
doctor, causes, risk factors, complications and so on. The second data source is database of AZ Symptoms website
(Azsymptoms.com., (2018)) where disease definitions, symptoms, causes, prevention, risk factors and
complications information included for 120+ diseases. After preprocessing, each user symptom is compared with
symptoms in symptom dataset. Python’s Fuzzy Wuzzy library is used for similarity checking. The resulting text
is saved to a new variable. These steps are both applied to the disease dataset and user text each symptom and
other data valued words including severity, duration, location, cause, accompanied by any other symptoms, change
in intensity are also extracted from written expression (as an individual expression or sentence structure of
symptoms) accordingly. The structure of collected data categorized in four main branches; symptoms, diseases,
tests (medical examinations) and corresponding treatments as described in Table1.
Text Extraction Engine to Upgrade…
| Volume 2 | Issue 3 | www.ijrtem.com | 14 |
Table 1. General structure of database table
Once tables are created symptoms are analyzed as input and they are trained by the process to detect possible
diagnoses, tests and treatments. Disease data table as indicated in Table 2 consists of ID, Name, Description,
Symptoms ID, Tests ID, Treatments ID, Risks, Causes, Preventions and Complications. Data content of
symptoms, tests and treatments are represented with numerical values in different databases and they are
embedded to system to analyze strength of the relationship.
ID 24
Name Leukemia
Description
Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and
the lymphatic system.
Symptoms ID 21,69,114,119,133,168,173,0,0,0,0,0,0,0,0
Test ID 8,94,104
Treatment ID 113,114,115,116,117
Risks
Factors that may increase your risk of developing some types of leukemia include:
Previous cancer treatment. People who've had certain types of chemotherapy and
radiation therapy for other cancers have an increased risk of developing certain types of
leukemia. Genetic disorders. Genetic abnormalities seem to play a role in the
development of leukemia. Certain genetic disorders, such as Down syndrome, are
associated with an increased risk of leukemia. Exposure to certain chemicals. Exposure
to certain chemicals, such as benzene — which is found in gasoline and is used by the
chemical industry — also is linked to an increased risk of some kinds of leukemia.
Smoking. Smoking cigarettes increases the risk of acute myelogenous leukemia. Family
history of leukemia. If members of your family have been diagnosed with leukemia,
your risk for the disease may be increased'
Causes
Scientists don`t understand the exact causes of leukemia. It seems to develop from a
combination of genetic and environmental factors.
Prevention None
Complications None
Gender Not gender restricted
Age Not age restricted
Table 2. Diseases table in database
Symptoms are identified by ID value, name, locations (neck, knee, eye, low back), level of the symptom which is
also indicated with numerical values (sharp, low, high, sudden, mild) and causes, and possible conditions for a
patient to visit the doctor. Table of tests (medical examinations) includes details about essential examinations` ID,
name, definition, why it is required (why is done), preparation, expectation, risks, results. On the other, hand table
of recommended treatments for the most related treatments are classified with as their ID numbers, names and
definitions.
Symptoms Diseases Tests Treatments
ID ID ID ID
Name Name Name Name
Nocation ID Description Definition Definition
Level ID Symptoms ID Why_ is_ done
Causes Test ID Preparation
See_ doctor Treatment ID Expectation
Risks Risks
Causes Results
Prevention
Complications
Gender
Age
Text Extraction Engine to Upgrade…
| Volume 2 | Issue 3 | www.ijrtem.com | 15 |
Implementations : A smart text extracting clinical decision support engine is developed to convert the clinical
data into significant and effective information. Python is used to develop the most efficient and appropriate model.
TextBlob is a library used for input and output processing, and for string matching which actually classifies input
symptoms as a disease. Two sets are used for classification, one including only symptoms, and the other the
matching diseases. Details about diseases such as treatments and tests are recommended, are stored in MySQL
database. The user is asked to enter his/her symptoms, and then the application converts the answer into Text Blob
object. Fuzzy String Matching, also called approximate string matching, is implemented as the process of finding
strings which approximately match a given pattern. The closeness of a match is often measured in terms of edit
distance which is the number of primitive operations necessary to convert the string into an exact match.
Preprocessing : Each symptom information is sent to the preprocessing module to prepare the data for the
analysis. First, stop words, punctuation characters and blank spaces are removed from the text. Then, each word
is stemmed by Porter’s Stemmer. The resulting text is saved to a new variable. These steps are both applied to the
disease dataset and user text
Training and testing : In training process text-based symptoms, patient`s personal information and past medical
history is used as input data. In the next step, data is trained for the possible detected diagnoses and recommend
appropriate treatment and as a result of training we expect to get out model output.
After the training process, the system is tested for various diagnoses and patients, then the percentage risk of
possible disease is represented as output information. Corresponding to this, treatments and recommendations
(any medical examinations, tests) are driven.
III. RESULTS AND CONCLUSION
A text extracting clinical decision support engine is developed to increase the accuracy of medical diagnosis. The
project may provide a significant help in clinical decision process which gives effective results even with patients
own words and in their own language. The behavior of different classifiers was tested in the context of the
problem. classifying inputted symptoms into predefined disease classes. The study was approached with three
different methods: using naïve Bayes, decision tree and Fuzzy Wuzzy library. The goal was to make a system that
will give as correct classification as possible regardless of spelling mistakes. Different inputs were tested to assess
the abilities supported by the Text Blob library. Output is based on the result obtained using Fuzzy Wuzzy library
regardless of some spelling mistakes that user might have done in giving input. After testing the system, an
accuracy of 90% has been accomplished. The impact on outcomes, assessing whether the project reduces time
from diagnosis to treatment, reduces cost, and improves quality the benefits of the study in global health care
environment.
Future Study Objectives: In process of developing the engine more detailed information about the patient will
also be collected to evaluate the model efficiently and give more accurate prediction of treatments and
recommendations. These are patients past medical history (allergies, medicines, surgeries, family history, diets,
and habits), birth and growth information, age, gender, height, weight. In order to improve the current system, we
also aim to upgrade the engine available without restriction of input language.
REFERENCES
1. Davis, D. a., Chawla, N. V., Blumm, N., Christakis, N., Barabasi, A.-L., & Barabási, A. (2008). Predicting
individual disease risk based on medical history. Proceeding of the 17th ACM Conference on Information
and Knowledge Mining - CIKM ’08, 769. https://doi.org/10.1145/1458082.1458185
2. Friedman, C., Shagina, L., Lussier, Y., & Hripcsak, G. (2004). Automated encoding of clinical documents
based on natural language processing. Journal of the American Medical Informatics Association, 11(5), 392–
402. https://doi.org/10.1197/jamia.M1552
3. Singh, H., & Sittig, D. F. (2015). Setting the record straight on measuring diagnostic errors. Reply to: “Bad
assumptions on primary care diagnostic errors” by Dr Richard Young. BMJ Quality & Safety, 24(5), 345.2-
348. https://doi.org/10.1136/bmjqs-2015-004140
4. Spyns, P., Nhàn, N. T., Baert, E., Sager, N., & De Moor, G. (1998). Medical language processing applied to
extract clinical information from dutch medical documents. Studies in Health Technology and Informatics.
https://doi.org/10.3233/978-1-60750-896-0-685
5. Tange, H. J., Schouten, H. C., Kester, A. D., & Hasman, A. (1998). The granularity of medical narratives and
its effect on the speed and completeness of information retrieval. Journal of the American Medical Informatics
Association : JAMIA, 5(6), 571–82. https://doi.org/10.1136/jamia.1998.0050571
Text Extraction Engine to Upgrade…
| Volume 2 | Issue 3 | www.ijrtem.com | 16 |
6. Steven Loria (2017). TextBlob: Simplified text processing [a Python (2 and 3) library for processing textual
data]. Retrieved from http://textblob.readthedocs.io/en/latest/index.html
7. Mayoclinic.org. (2018). Diseases and Conditions - Disease and condition information from Mayo Clinic
experts. [online] Available at: https://www.mayoclinic.org/diseases-conditions/index [Accessed 24 Feb.
2018].
8. Azsymptoms.com. (2018). Medical Symptoms: Online Encyclopedia of Medical Symptoms and Conditions.
[online] Available at: http://www.azsymptoms.com/ [Accessed 24 Feb. 2018].

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Text Extraction Engine to Upgrade Clinical Decision Support System

  • 1. Invention Journal of Research Technology in Engineering & Management (IJRTEM) ISSN: 2455-3689 www.ijrtem.com Volume 2 Issue 3 ǁ March. 2018 ǁ PP 13-16 | Volume 2 | Issue 3 | www.ijrtem.com | 13 | Text Extraction Engine to Upgrade Clinical Decision Support System Merve Kevser Gökgöl 1 , Zeynep Orhan 2 , Ajla Kirlić 3 1,2 Department of Information Technologies, International Burch University, Sarajevo, Bosnia and Herzegovina 3 Department of Engineering, American University in Bosnia and Herzegovina ABSTRACT : New generation technological improvements lead patients to search their symptoms and corresponding diagnosis on online resources. In this study, it is aimed to develop a machine learning model to suit in different availability of users. Most of the current systems allow people to choose related symptom in web interfaces. In addition to these applications it is aimed to implement a new technique which extracts the text-based symptoms and its related parameters such as, severity, duration, location, cause, accompanied by any other indicators. This study is applicable for patient`s everyday language statements besides medical expression of symptoms for corresponding symptoms which is also supporting initial clinical decision system. Extracted terms are analyzed for matching diagnosis where an accuracy of 90% has been accomplished. KEYWORDS : Medical diagnosis, symptom extraction, public healthcare, machine learning I. INTRODUCTION The era of digitization has led computers to become the real face of handling commercial processes across a wealth of industries. As institutions today specifically in the medical domain have resorted to these virtual machines for realizing their goals, more and more medical data is being generated on a continuous basis (Davis et al., 2008). Current systems are challenging to optimize the utilization of existing medical data resources in automated diagnostics. The detection and interpretation of pathological conditions usually required large number of experts available, however the number of experts is sometimes not enough, and other problems may appear such as disagreement among experts (Spyns et al., 1998). The electronic patient records contains a rich source of valuable clinical information, which could be used for a wide range of automated applications aimed at improving the health care process, such as alerting for potential medical errors, generating a patient problem list, and assessing the severity of a condition (Friedman et al., 2004). However, these applications are not applicable since large amount of information is in textual form (Tange et al., 1998). II. METHODOLOGY In this study, process of data collection allows patients to enter their symptoms by typing in everyday language. Therefore, to increase the accuracy firstly it is required to clean and eliminate insignificant words, such as stop words and vague abbreviations. From highest to lowest, predicted diseases are printed on the screen with matched symptoms. Data Set : We have considered two sources for disease data. One of them is Mayo Clinic website (Mayoclinic.org., (2018)) which contains highly detailed information about diseases: disease overview, symptoms, when to see a doctor, causes, risk factors, complications and so on. The second data source is database of AZ Symptoms website (Azsymptoms.com., (2018)) where disease definitions, symptoms, causes, prevention, risk factors and complications information included for 120+ diseases. After preprocessing, each user symptom is compared with symptoms in symptom dataset. Python’s Fuzzy Wuzzy library is used for similarity checking. The resulting text is saved to a new variable. These steps are both applied to the disease dataset and user text each symptom and other data valued words including severity, duration, location, cause, accompanied by any other symptoms, change in intensity are also extracted from written expression (as an individual expression or sentence structure of symptoms) accordingly. The structure of collected data categorized in four main branches; symptoms, diseases, tests (medical examinations) and corresponding treatments as described in Table1.
  • 2. Text Extraction Engine to Upgrade… | Volume 2 | Issue 3 | www.ijrtem.com | 14 | Table 1. General structure of database table Once tables are created symptoms are analyzed as input and they are trained by the process to detect possible diagnoses, tests and treatments. Disease data table as indicated in Table 2 consists of ID, Name, Description, Symptoms ID, Tests ID, Treatments ID, Risks, Causes, Preventions and Complications. Data content of symptoms, tests and treatments are represented with numerical values in different databases and they are embedded to system to analyze strength of the relationship. ID 24 Name Leukemia Description Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system. Symptoms ID 21,69,114,119,133,168,173,0,0,0,0,0,0,0,0 Test ID 8,94,104 Treatment ID 113,114,115,116,117 Risks Factors that may increase your risk of developing some types of leukemia include: Previous cancer treatment. People who've had certain types of chemotherapy and radiation therapy for other cancers have an increased risk of developing certain types of leukemia. Genetic disorders. Genetic abnormalities seem to play a role in the development of leukemia. Certain genetic disorders, such as Down syndrome, are associated with an increased risk of leukemia. Exposure to certain chemicals. Exposure to certain chemicals, such as benzene — which is found in gasoline and is used by the chemical industry — also is linked to an increased risk of some kinds of leukemia. Smoking. Smoking cigarettes increases the risk of acute myelogenous leukemia. Family history of leukemia. If members of your family have been diagnosed with leukemia, your risk for the disease may be increased' Causes Scientists don`t understand the exact causes of leukemia. It seems to develop from a combination of genetic and environmental factors. Prevention None Complications None Gender Not gender restricted Age Not age restricted Table 2. Diseases table in database Symptoms are identified by ID value, name, locations (neck, knee, eye, low back), level of the symptom which is also indicated with numerical values (sharp, low, high, sudden, mild) and causes, and possible conditions for a patient to visit the doctor. Table of tests (medical examinations) includes details about essential examinations` ID, name, definition, why it is required (why is done), preparation, expectation, risks, results. On the other, hand table of recommended treatments for the most related treatments are classified with as their ID numbers, names and definitions. Symptoms Diseases Tests Treatments ID ID ID ID Name Name Name Name Nocation ID Description Definition Definition Level ID Symptoms ID Why_ is_ done Causes Test ID Preparation See_ doctor Treatment ID Expectation Risks Risks Causes Results Prevention Complications Gender Age
  • 3. Text Extraction Engine to Upgrade… | Volume 2 | Issue 3 | www.ijrtem.com | 15 | Implementations : A smart text extracting clinical decision support engine is developed to convert the clinical data into significant and effective information. Python is used to develop the most efficient and appropriate model. TextBlob is a library used for input and output processing, and for string matching which actually classifies input symptoms as a disease. Two sets are used for classification, one including only symptoms, and the other the matching diseases. Details about diseases such as treatments and tests are recommended, are stored in MySQL database. The user is asked to enter his/her symptoms, and then the application converts the answer into Text Blob object. Fuzzy String Matching, also called approximate string matching, is implemented as the process of finding strings which approximately match a given pattern. The closeness of a match is often measured in terms of edit distance which is the number of primitive operations necessary to convert the string into an exact match. Preprocessing : Each symptom information is sent to the preprocessing module to prepare the data for the analysis. First, stop words, punctuation characters and blank spaces are removed from the text. Then, each word is stemmed by Porter’s Stemmer. The resulting text is saved to a new variable. These steps are both applied to the disease dataset and user text Training and testing : In training process text-based symptoms, patient`s personal information and past medical history is used as input data. In the next step, data is trained for the possible detected diagnoses and recommend appropriate treatment and as a result of training we expect to get out model output. After the training process, the system is tested for various diagnoses and patients, then the percentage risk of possible disease is represented as output information. Corresponding to this, treatments and recommendations (any medical examinations, tests) are driven. III. RESULTS AND CONCLUSION A text extracting clinical decision support engine is developed to increase the accuracy of medical diagnosis. The project may provide a significant help in clinical decision process which gives effective results even with patients own words and in their own language. The behavior of different classifiers was tested in the context of the problem. classifying inputted symptoms into predefined disease classes. The study was approached with three different methods: using naïve Bayes, decision tree and Fuzzy Wuzzy library. The goal was to make a system that will give as correct classification as possible regardless of spelling mistakes. Different inputs were tested to assess the abilities supported by the Text Blob library. Output is based on the result obtained using Fuzzy Wuzzy library regardless of some spelling mistakes that user might have done in giving input. After testing the system, an accuracy of 90% has been accomplished. The impact on outcomes, assessing whether the project reduces time from diagnosis to treatment, reduces cost, and improves quality the benefits of the study in global health care environment. Future Study Objectives: In process of developing the engine more detailed information about the patient will also be collected to evaluate the model efficiently and give more accurate prediction of treatments and recommendations. These are patients past medical history (allergies, medicines, surgeries, family history, diets, and habits), birth and growth information, age, gender, height, weight. In order to improve the current system, we also aim to upgrade the engine available without restriction of input language. REFERENCES 1. Davis, D. a., Chawla, N. V., Blumm, N., Christakis, N., Barabasi, A.-L., & Barabási, A. (2008). Predicting individual disease risk based on medical history. Proceeding of the 17th ACM Conference on Information and Knowledge Mining - CIKM ’08, 769. https://doi.org/10.1145/1458082.1458185 2. Friedman, C., Shagina, L., Lussier, Y., & Hripcsak, G. (2004). Automated encoding of clinical documents based on natural language processing. Journal of the American Medical Informatics Association, 11(5), 392– 402. https://doi.org/10.1197/jamia.M1552 3. Singh, H., & Sittig, D. F. (2015). Setting the record straight on measuring diagnostic errors. Reply to: “Bad assumptions on primary care diagnostic errors” by Dr Richard Young. BMJ Quality & Safety, 24(5), 345.2- 348. https://doi.org/10.1136/bmjqs-2015-004140 4. Spyns, P., Nhàn, N. T., Baert, E., Sager, N., & De Moor, G. (1998). Medical language processing applied to extract clinical information from dutch medical documents. Studies in Health Technology and Informatics. https://doi.org/10.3233/978-1-60750-896-0-685 5. Tange, H. J., Schouten, H. C., Kester, A. D., & Hasman, A. (1998). The granularity of medical narratives and its effect on the speed and completeness of information retrieval. Journal of the American Medical Informatics Association : JAMIA, 5(6), 571–82. https://doi.org/10.1136/jamia.1998.0050571
  • 4. Text Extraction Engine to Upgrade… | Volume 2 | Issue 3 | www.ijrtem.com | 16 | 6. Steven Loria (2017). TextBlob: Simplified text processing [a Python (2 and 3) library for processing textual data]. Retrieved from http://textblob.readthedocs.io/en/latest/index.html 7. Mayoclinic.org. (2018). Diseases and Conditions - Disease and condition information from Mayo Clinic experts. [online] Available at: https://www.mayoclinic.org/diseases-conditions/index [Accessed 24 Feb. 2018]. 8. Azsymptoms.com. (2018). Medical Symptoms: Online Encyclopedia of Medical Symptoms and Conditions. [online] Available at: http://www.azsymptoms.com/ [Accessed 24 Feb. 2018].