2. What is Thalassemia?
• Thalassaemia is a genetic disorder which is
inherited from parents.
• The marriage of two Thalassaemic carriers
could result in the birth of a Thalassaemia
major who requires blood transfusions once a
month or every three weeks in order to stay
alive.
3. Types of thalassemia
• Beta thalassemia carrier
Beta thalassemia major
Beta thalassemia minor
• Alpha thalassemia carrier
Alpha thalassemia plus
Alpha thalassemia zero
Difference between alpha thalassemia and beta thalassemia
Alpha thalasemia occurs if there are problems with some or
all of the alph-globin genes. Beta thalasemia occurs when
there are problems with one or both of the beta-globin genes
4. 7 facts about thalassemia
• 1. Thalassemia is a disorder of the blood
5. • 2. Thalassemia is a hereditary disorder, it is
passed on from parents to children through
the genes
6. • 3. Thalassemia is a haemoglobin disorder
• It is a disorder that doesn’t allow the protein
of the red blood cells to carry enough oxygen
around the body and keep it healthy
7. • 4. Approximately 7% of the global population
is a carrier of a severe haemoglobin disorder,
includin thalassemia
• 5. Between 300000 to 500000 children are
born annually with a severe haemoglobin
disorder
8. • 6. About 80% of affected children are born in
middle and low income countries
• 7. And most importantly, thalassemia is today
both preventable and treatable!
9. Status of Thalassemia in the Maldives
It was found that in Maldives, 18% of the population were
affected with this trait with one in every 120 births being a
Thalassaemia major.
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12. Treatment…
• Blood Transfusions. Transfusions of red blood
cells are the main treatment for people who
have moderate or severe thalassemia. ...
• Iron Chelation Therapy. The hemoglobin in red
blood cells is an iron-rich protein. ...
• Folic Acid Supplements. ...
• Blood and Marrow Stem Cell Transplant.
13.
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