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Griffith Experiment
DNA as a Genetic Material
PRESENTED BY
GAZAN FAR ALI
I.M.SC. MICROBIOLOGY
SACRED HEART COLLEGE(AUTONOMOUS)
TIRUPATTUR
Genetic Material
Frederick Griffith: Bacterial transformation
In 1928, British bacteriologist Frederick Griffith conducted a
series of experiments using Streptococcus
pneumoniae bacteria and mice. Griffith wasn't trying to
identify the genetic material, but rather, trying to develop a
vaccine against pneumonia. In his experiments, Griffith used
two related strains of bacteria, known as R and S.
•When Griffith infected mice with the non-virulent bacteria
(strain R), the mice survived
•When Griffith infected mice with the virulent bacteria
(strain S), the mice died
•When Griffith infected mice with heat-killed virulent bacteria
(strain R), the mice survived as the bacteria had been killed
•When Griffith infected mice with a mix of heat-killed
strain S and living strain R, the mice were found to have died
Giriffith Experiment
Giriffith experiment (1).pptx
Giriffith experiment (1).pptx

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Giriffith experiment (1).pptx

  • 1. Griffith Experiment DNA as a Genetic Material PRESENTED BY GAZAN FAR ALI I.M.SC. MICROBIOLOGY SACRED HEART COLLEGE(AUTONOMOUS) TIRUPATTUR
  • 3. Frederick Griffith: Bacterial transformation In 1928, British bacteriologist Frederick Griffith conducted a series of experiments using Streptococcus pneumoniae bacteria and mice. Griffith wasn't trying to identify the genetic material, but rather, trying to develop a vaccine against pneumonia. In his experiments, Griffith used two related strains of bacteria, known as R and S.
  • 4.
  • 5. •When Griffith infected mice with the non-virulent bacteria (strain R), the mice survived •When Griffith infected mice with the virulent bacteria (strain S), the mice died •When Griffith infected mice with heat-killed virulent bacteria (strain R), the mice survived as the bacteria had been killed •When Griffith infected mice with a mix of heat-killed strain S and living strain R, the mice were found to have died