Satya Nadella's leadership at Microsoft focused on cloud services, increasing revenue from $16.6 billion in 2011 to $20.3 billion by June 2013. Dynamics 365 integrates ERP and CRM functionalities, offering various modules like sales, customer service, project service automation, and financials to streamline business operations. Additionally, it provides tools such as Microsoft Power Apps and Power BI for enhanced analytics and custom workflows.