copper, overload of copper, illness

1. Role of copper in our body
Made by:
Magdalena Wnuk
Nicolas Węgrzyn

3. Dietary reference intakes for copper
Tolerable Upper Intake Levels (UL)**
Age Male Female Pregnant Lactating
1-3 yrs. 1000 µg 1000 µg
4-8 3000 µg 3000 µg
9-13 5000 µg 5000 µg
14-18 8000 µg 8000 µg 8000 µg 8000 µg
19-50 10000 µg 10000 µg 10000 µg 10000 µg
51-70 10000 µg 10000 µg
70+ 10000 µg 10000 µg
**UL = The maximum level of daily nutrient intake that is likely to pose
no risk of adverse effects. Unless otherwise specified, the UL
represents total intake from food, water, and supplements.

4. Top 10 foods highest in copper
1: Liver
2: Oysters
3: Sesame Seeds and Tahini
4: Cocoa Powder and Chocolate
5: Nuts
6: Calamari and Lobster
7: Sunflower Seeds
8: Sun Dried Tomatoes
9: Roasted Pumpkin and Squash Seeds
10: Dried Herb

5. How much do we really eat everyday?
Breakfast: Lunch:
• Flakes (52g) – 1,1mg • Salad (55g) – 0mg
• Juice (250g) – 0,3mg • Beef (160g) – 23mg
• Milk (250g) – no data • Potatos (180g) – 0mg
• Yogurt (150g) – 0,1mg • Dark chocolate (100g) – 1,8mg
Dinner:
• Veal (100g) – 12mg
• Buckwheat (170g) – 1,9mg
• Pineapple (240g) – 0,3mg
Summary – the real daily consumption of copper approximately is – 40,5mg

6. Clinical Effects of Inadequate Intake
Frank copper deficiency in humans is rare, but has been found in a
number of special conditions. It has been observed:
• premature infants fed milk formulas
• infants recovering from malnutrition associated with chronic
diarrhea and fed cow’s milk
Symptoms accompanying the copper deficiency :
• normocytic
• hypochromic anemia
• leukopenia
• neutropenia
• osteoporosis

7. Factors affecting the copper requirement
Zinc
Zinc intakes, well in excess of the amount normally found in the diet,
can decrease copper absorption in adults

8. Factors affecting the copper requirement
Iron
High iron intakes may interfere with copper absorption in infants:
• low concentrations of iron absorbed more copper
• higher iron concentration less absorption

9. Factors affecting the copper requirement
Fructose
Studies in rats demonstrated that diets very high in fructose were
associated with increased severity of copper deficiency in rats, but a
similar effect was not observed in pigs

10. Osteoporosis
One factor contributing to bone density loss in the elderly may be subclinical
magnesium (Mg), zinc (Zn) and/or copper (Cu) deficiencies due to a reduced
dietary intake and reduced absorption of these micronutrients. Mg, Zn
and Cu are essential cofactors for enzymes involved in thesynthesis of
various bone matrix constituents.
Normal Osteopenia Osteoporosis
Copper (mg/l) 1.60 ± 0.08 1.59 ± 0.09 1.54 ± 0.12

11. Thank You for Your Atention